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Meds for Depression
MEDICATIONS AFFECTING THE NERVOUS SYSTEM
| Question | Answer |
|---|---|
| DEPRESSION IS WHAT KIND OF DISORDER | A MOOD/AFFECTIVE |
| RELIEF OF SYMPTOMS OF DEPRESSION WITH ANTI-DEPRESSANT THERAPY CAN TAKE HOW LONG | 1-3 WEEKS |
| WHEN CAN YOU EXPECT THE FULL BENEFITS OF ANTI-DEPRESSANT THERAPY TO TAKE PLACE | 2-3 MONTHS |
| WHAT ARE THE FOUR MAIN GROUPS OF ANTI-DEPRESSANT MEDICATIONS | TCA'S/TRICYCLIC ANTI-DEPRESSANTS SSRI'S/SELECTIVE SEROTONIN REUPTAKE INHIBITORS MOAI'S/MONOAMINE OXIDASE INHIBITORS ATYPICAL ANTIDEPRESSANTS |
| WHAT MEDICATIONS ARE UNDER THE CLASSIFICATION OF TCA'S | AMITRIPTYLINE/ELAVIL IMIPRAMINE/TOFRANIL DOXEPIN/SINEQUAN NORTRIPTYLINE/AVENTYL TRIMIPRAMINE/SURMONTIL |
| WHAT IS THE EXPECTED PHARMACOLOGICAL ACTION OF TCA'S | BLOCK REUPTAAKE OF NOREPINEPHRINE AND SEROTONIN IN THE SYNAPTIC SPACE THEREBY INTENSIFYING THE EFFECTS OF THESE NEUROTRANSMITTERS |
| WHAT ARE THE THERAPEUTIC EFFECTS OF TCA'S | DEPRESSION DEPRESSIVE EPISODES OF BIPOLAR DISORDER CHRONIC PAIN ENURESIS |
| WHAT ARE THE SIDE EFFECTS OF USING TCA'S | ORTHOSTATIC HYPOTENSION ANTICHOLINERGIC EFFECTS SEDATION TOXICITY DECREASED SEIZURE THRESHOLD EXCESSIVE SWEATING |
| WHAT ARE THE ANTICHOLINERGIC EFFECTS OF TCA'S | DRY MOUTH BLURRED VISION PHOTOPHOBIA URINARY HESITANCY OR RETENTION CONSTIPATION TACHYCARDIA |
| WHAT KIND OF TOXICITY RESULTS FROM USING TCA'S | CHOLINERGIC BLOCKADE AND CARDIAC TOXICITY EVIDENCED BY DYSRHYTHMIAS MENTAL CONFUSION AGITATION FOLLOWED BY SEIZURES COMA POSSIBLE DEATH |
| TCA'S ARE A PREGNANCY CATEGORY RISK? | C |
| TCA'S ARE CONTRAINDICATED IN CLIENTS THAT ? | HAVE SEIZURE DISORDERS |
| TCA'S ARE USED CAUTIOUSLY IN CLIENTS WITH | CORONARY ARTERY DISEASE DIABETES LIVER DISORDER KIDNEY DISORDER RESPIRATORY DISORDER URINARY RETENTION AND OBSTRUCTION ANGLE-CLOSURE GLAUCOMA BENIGN PROSTATIC HYPERTROPHY HYPERTHYROIDISM |
| INTERACTIONS WITH TCA'S INCLUDE | MAOI'S AND ST JOHNS WORT = SEROTONIN SYNDROME ANTIHISTAMINES = ADDITIVE ANTICHOLINERGIC EFFECTS TCA'S DECREASE EPHEDRINE, AMPHETAMINE EFFECTS ALCOHOL, ANTIHISTAMINES, BENZO'S, OPIOIDS = ADDED CNS DEPRESSANT INCREASED EFFECTS OF EPINEPHRINE, DOPAMINE |
| MEDICATIONS CLASSIFIED AS SSRI'S ARE | FLUOXETINE/PROZAC CITALOPRAM/CELEXA ESCITALOPRAM/LEXAPRO PAROXETINE/PAXIL SERTRALINE/ZOLOFT |
| WHAT IS THE EXPECTED PHARMACOLOGICAL ACTION OF SSRI'S | SELECTIVELY BLOCK REUPTAKE OF THE MONOAMINE NEUROTRANSMITTER SEROTONIN IN THE SYNAPTIC SPACE THEREBY INTENSIFYING THE EFFECTS OF SEROTONIN |
| THERAPEUTIC USES OF SSRI'S ARE | MAJOR DEPRESSION OCD BULIMIA NERVOSA PMDD PANIC DISORDER PTSD |
| SIDE EFFECTS OF SSRI'S ARE | SEXUAL DYSFUNCTION CNS STIMULATION WEIGHT LOSS (EARLY IN THERAPY) WEIGHT GAIN (IN LATER THERAPY) SEROTONIN SYNDROME WITHDRAWAL SYMPTOMS HYPONATREMIA RASH SLEEPINESS FAINTNESS LIGHTHEADEDNESS GI BLEEDING BRUXISM |
| SEROTONIN SYNDROME MAY BEGIN WHEN | 2-72 HOURS AFTER STARTING THERAPY AND MAY BE LETHAL |
| SIDE EFFECTS ASSOCIATED WITH SEROTONIN SYNDROME | MENTAL CONFUSION DIFFICULTY CONCENTRATING FEVER AGITATION ANXIETY HALLUCINATIONS INCOORDINATION HYPERREFLEXIA DIAPHORESIS TREMORS |
| WITHDRAWAL SYMPTOMS ASSOCIATED WITH SSRI'S ARE | HEADACHE NAUSEA VISUAL DISTURBANCES ANXIETY DIZZINESS TREMORS |
| FLUOXETINE IS A PREGNANCY RISK CATEGORY | C |
| FLUOXETINE AND PAROXETINE MAY INCREASE THE RISKS OF WHAT | BIRTH DEFECTS |
| SSRI'S ARE CONTRAINDICATED IN CLIENTS TAKING | MAOI'S AND TCA'S |
| SSRI'S ARE USED CAUTIOUSLY IN CLIENTS WITH | LIVER DYSFUNCTION RENAL DYSFUNCTION CARDIAC DISEASE SEIZURE DISORDERS DIABETES ULCERS HISTORY OF GI BLEEDING TAKING NSAIDS TAKING ANTI-COAGULANTS |
| MAOI'S AND ST JOHNS WORT INCREASE THE RISK OF | SEROTONIN SYNDROME |
| FLUOXETINE CAN DISPLACE WARFARIN/COUMADIN FROM BOUND PROTEIN AND RESULT IN WHAT | INCREASED WARFARIN LEVELS |
| FLUOXETINE CAN INCREASE THE LEVELS OF TCA'S AND WHAT | LITHIUM |
| FLUOXETINE SUPPRESSES PLATELET AGGREGATION AND THUS INCREASES THE RISK OF BLEEDING WHEN USED WITH WHAT | NSAID'S AND ANTI-COAGULANTS |
| MEDICATIONS IN THE MAOI CLASS ARE | PHENELZINE/NARDIL ISOCARBOXAZID/MARPLAN TRANYLCYPROMINE/PARNATE SELEGILINE/EMSAM-TRANSDERMAL MAOI |
| THE EXPECTED PHARMACOLOGICAL ACTION OF MAOI'S IS | BLOCK THE MAO-A IN THE BRAIN THEREBY INCREASING THE AMOUNT OF NOREPINEPHRINE, DOPAMINE, SEROTONIN AVAILABLE FOR TRANSMISSION OF IMPULSES THIS INTENSIFIES THE RESPONSE AND RELIEVES DEPRESSION |
| THERAPEUTIC USES OF MAOI'S ARE | ATYPICAL DEPRESSION BULIMIA NERVOSA OCD |
| SIDE EFFECTS OF MAOI'S INCLUDE | CNS STIMULATION ORTHOSTATIC HYPOTENSION HYPERTENSIVE CRISIS LOCAL RASH WITH TRANSDERMAL USE |
| WHAT ARE THE SPECIFIC SIDE EFFECTS ASSOCIATED WITH THE CNS STIMULATION | ANXIETY AGITATION MANIA HYPOMANIA |
| WHAT CAUSES THE HYPERTENSIVE CRISIS ASSOCIATED WITH USE OF MAOI'S | TYRAMINE CONTAINING FOODS |
| WHAT ARE THE SIDE EFFECTS OF HYPERTENSIVE CRISIS ASSOCIATED WITH THE USE OF TYRAMINES AND MAOI'S | HEADACHE NAUSEA INCREASED HEART RATE INCREASED BLOOD PRESSURE |
| MAOI'S ARE PREGNANCY RISK CATEGORY | C |
| MAOI'S ARE CONTRAINDICATED IN WHAT TYPE OF CLIENTS | TAKING SSRI'S THOSE WITH PHEOCHROMOCYTOMA CARDIOVASCULAR DISEASE CEREBRAL VASCULAR DISEASE SEVERE RENAL INSUFFICENCY |
| MAOI'S ARE USED CAUTIOUSLY IN CLIENTS WITH | DIABETES SEIZURE DISORDERS TAKING TCA'S |
| TRANSDERMAL SELEGILINE/EMSAM IS CONTRAINDICATED IN CLIENTS TAKING | CARBAMAZEPINE/TEGRETOL OXCARBAZEPINE/TRILEPTAL WHICH MAY INCREASE THE BLOOD LEVELS OF THE MAOI |
| INTERACTIONS WITH MAOI'S | INDIRECT ACTING SYMPATHOMIMETIC MEDICATIONS TCA'S SSRI'S MEPERIDINE/DEMEROL TYRAMINE RICH FOODS VASOPRESSORS |
| INDIRECT ACTING SYMPATHOMIMETIC MEDICATIONS PROMOTE THE RELEASE OF NOREPINEPHRINE AND CAN LEAD TO WHAT | HYPERTENSIVE CRISIS |
| USE OF TCA'S AND MAOI'S CAN LEAD TO WHAT | HYPERTENSIVE CRISIS |
| USE OF SSRI'S AND MAOI'S CAN LEAD TO WHAT | SEROTONIN SYNDROME |
| ANTIHYPERTENSIVES AND MAOI'S HAVE A ADDITIVE WHAT EFFECT | HYPOTENSIVE |
| MEPERIDINE/DEMEROL AND MAOI'SCAN LEAD TO WHAT | HYPERPYREXIA |
| CONCURRENT USE OF VASOPRESSORS AND MAOI'S RESULT IN WHAT | HYPERTENSION |
| WHAT ARE MEDICATIONS THAT ARE LISTED AS ATYPICAL ANTIDEPRESSANTS | BUPROPRION HCL/WELLBUTRIN |
| WHAT IS THE EXPECTED PHARMACOLOGICAL ACTION OF ATYPICAL ANTI-DEPRESSANTS | INHIBITING DOPAMINE UPTAKE |
| THERAPEUTIC USES OF ATYPICAL ANTI-DEPRESSANTS ARE | TREATMENT OF DEPRESSION ALTERNATIVE TO SSRI'S FOR CLIENTS UNABLE TO TOLERATE SEXUAL DYSFUNCTION SIDE EFFECTS OF SSRI'S AID TO QUIT SMOKING PREVENTION OF SAD |
| SIDE EFFECTS OF ATYPICAL ANTI-DEPRESSANTS | HEADACHE DRY MOUTH GI DISTRESS CONSTIPATION INCREASED HEART RATE NAUSEA RESTLESSNESS INSOMNIA SUPRESSION OF APPETITE WEIGHT LOSS SEIZURES |
| BUPROPRION HCL/WELLBUTRIN IS A PREGNANCY RISK CATEGORY WHAT | B |
| ATYPICAL ANTI-DEPRESSANTS ARE CONTRAINDICATED IN CLIENTS THAT ARE | TAKING MAOI'S |
| ATYPICAL ANTI-DEPRESSANTS ARE USED CAUTIOUSLY IN CLIENTS WHO HAVE | SEIZURE DISORDERS |
| ATYPICAL ANTI-DEPRESSANTS INTERACT WITH MAOI'S AND INCREASE THE RISK OF | TOXICITY |
| OTHER ATYPICAL ANTIDEPRESSANTS ARE | VENLAFAXINE/EFFEXOR DULOXETINE/CYMBALTA (SNRI'S) MIRTAZAPINE/REMERON REBOXETINE/EDRONAX TRAZADONE/DESYREL |
| EFFEXOR AND CYMBALTA'S PHARMACOLOGICAL ACTION IS | INHIBIT SEROTONIN AND NOREPINEPHRINE REUPTAKE THEREBY INCREASING THE AMOUNT OF THESE NEUROTRANSMITTERS AVAILABLE IN BRAIN IMPULSE TRANSMISSION |
| MIRTAZAPINE/REMERON'S PHARMACOLOGICAL ACTION | INCREASE RELEASE OF SEROTONIN AND NOREPINEPHRINE AND THEREBY INCREASING THE AMOUNT OF NEUROTRANSMITTERS AVAILABLE FOR IMPULSE TRANSMISSION |
| REBOXETINE/EDRONAX'S PHARMACOLOGICAL ACTION | SELECTIVELY INHIBITS THE REUPTAKE OF NOREPINEPHRINE THEREBY INCREASING THE AMOUNT OF NEUROTRANSMITTERS AVAILABLE FOR IMPULSE TRANSMISSION |
| TRAZADONE/DESYREL'S PHARMACOLOGICAL ACTION | HAS MODERATE SELECTIVE BLOCKADE OF SEROTONIN RECEPTORS WHICH ALLOWS MORE SEROTONIN TO BE AVAILABLE FOR IMPULSE TRANSMISSION |
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