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Genetics & Cell Func
cell cycle, protein synthesis
| Question | Answer |
|---|---|
| DNA | deoxyribosenucleic acid; contains phosphate group, pentose, nitrogenous base |
| Nucleotide | monomer of DNA |
| Nitrogenous bases | adenine, guanine, thymine, cytosine |
| Deoxyribose | |
| Double helix | shape of DNA |
| Complementary base pairing | connected by hydrogen bond; adenine & thymine; guanine & cytosine |
| Histones | compact and control the long threads of DNA |
| Nucleosomes | repeating subunits of chromatin, consisting of a DNA chain coiled around a core of histones; beads on a string |
| Chromatin | part of the nucleus that consists of DNA and proteins |
| Genes | A segment of DNA, occupying a specific place on a chromosome |
| Chromosome | linear strand of DNA and associated proteins in the nucleus of eukaryotic cells that carries the genes and functions in the transmission of hereditary information. |
| Genetic code | The sequence of nucleotides in DNA or RNA that determines the specific amino acid sequence in the synthesis of proteins. |
| Codon | 3 base pairs & 1 amino acids; determines the insertion of a specific amino acid in a polypeptide chain during protein synthesis or the signal to stop protein synthesis. |
| RNA | has ribose sugar that contains oxygen; single stranded |
| Ribose | a pentose sugar |
| Uracil | rnas replacement for thymine |
| mRNA | carries info from DNA in the nucleus to the ribosome sites of protein synthesis in the cell |
| tRNA | transmits genetic information from DNA to the cytoplasm |
| rRNA | forms part of the protein-synthesizing organelle known as a ribosome |
| Protein synthesis | creation of proteins using DNA and RNA |
| Transcription | constructing a mrna using dna as template. gentic info transferred to the mrna. |
| Pre mRNA | immature single strand of messenger ribonucleic acid |
| Splicing | modification of pre-mRNA taking place after transcription, in which introns are removed and exons are joined. |
| Exons | The protein-coding region in the DNA that are spliced together |
| Introns | The protein-coding region in the DNA that are spliced away |
| Translation | mrna produced by transcription is decoded by the ribosome to produce a specific amino acid chain, or polypeptide, that will later fold into an active protein. |
| Ribosome | components of cells that make proteins from all amino acids |
| Polyribosome | cluster of ribosomes, bound to a mRNA molecule |
| Cell cycle | series of events that takes place in a cell leading to its division replication |
| Interphase | preparing for cell division; in crease in size and copies dna |
| Gap 1 phase | cell grows to prep for cell division |
| (S)ynthesis phase | dna synthesis and replication |
| DNA replication | process to copy DNA. |
| Gap 2 phase | cell growth and prep for mitosis |
| Mitotic phase | phase of the cell cycle that includes mitosis and cytokinesis. |
| Mitosis | cell separates the chromosomes in its cell nucleus into two identical sets in two nuclei |
| Cytokinesis | cytoplasm of a cell is divided to form 2 daughter cells. |
| Cell cycle checkpoints | G1 (Restriction) Checkpoint; G2 Checkpoint ; Metaphase Checkpoint |
| Cyclin dependent kinases | a family of protein kinases (enzymes) |
| Cyclin | control the progression of cells through the cell cycle by activating cyclin-dependent kinase |
| Maturation promoting factors | a protein complex that in its active form causes cells to undergo mitosis |
| How is DNA similar to other macromolecules? Different? | DNA is a nucleic acid (macromolecule) made up of nucleotides (molecules) like others. It carries genetic information. |
| How do hydrogen bonds play a role in DNA form and function? | The double helical structure of DNA is due to hydrogen bonding between the base pairs. weak enough to be broken easily during replication. |
| What is the genetic code and how does it allow gene expression to occur? | The sequence of nucleotides in DNA or RNA that determines the specific amino acid sequence in the synthesis of proteins. |
| How does RNA differ from DNA? | rna has ribose sugar that contains oxygen & dna doesnt ; dna= thymine, rna=uracil ; dna = double stranded, rna = single stranded |
| Why is cell cycle control useful? How does cyclin allow for this control? | To control cell replication. control the progression of cells through the cell cycle by activating cyclin-dependent kinase |