Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards




share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Chapter 9 pharmacolo

drug therapy during pregnancy and breast feeding

QuestionAnswer
About 2/3 of pregnant women take at least one medication
Medication Exposure in Pregnancy Risk Evaluation Program 2009, FDA's new program to increase healthcare professionals' knowledge of drug risks during pregnancy
Pregnancy brings on the physiolgic changes in the kidneys, liver and gastrointestinal tract(thus a compensatory change)
During pregnancy, the tone and motility of the bowel decreases (allowing more drugs to be absorbed)
True of False: more time is available for reabsorption of drugs that undergo enterohepatic recirculation. Therefore the effects are prolonged true
Essentially all drugs can cross the placenta
The cliniciian should assume that any drug taken will reach the fetus
lipid soluble drugs cross the placenta readily, while drugs that are _______ have more difficulty ionized, polar, protein bound
teratogenesis the development of birthdefects
Gross malformations produced by exposure to teratogens during embryonic period
exposure during the fetal period usually disrupts FUNCTION rater than gross anatomy
It is important to note that lack of proof of teratogenicity does not mean that a drug is safe
in 1983, the FDA established a system for classifying drugs according to their probable risk categories: ABCD and X (A is the least dangerous)
The new proposed system under FDA will have three sections: 1.)Fetal risk summary, 2.) Clinical Considerations. 3.) Data
Fetal Risk Summary will describe what is known about a drugs' effects on the fetus and will offer a conclusion on safety during pregancy
Clinical Considerations describe the likely effects if a drug is taken before a woman knows that she is pregnant.
Data will detail the evidence from human and animal studies that supports the information in the fetal risk summary
Any woman of reproductive age who takes a known teratogen must be counseled about the risk and necessity of using at least one form of birth control
Drugs that are lipid soluble readily enter breast milk
Drugs that do not enter breast milk are ionized, polar, and protein bound
Although most drugs can de detected in milk concentrations are usually too low to harm the nursing
Steps 1-3 taken to minimize the risk to the infant 1.) dosing immediately AFTER feeding 2.) avoiding drugs that have a long half life 3.) avoiding sustained release formulations
Steps 4-7 taken to minimize the risk to infant 4.) choosing drugs that tend to be excluded from milk 5.) choosing drugs that are least likely to effect infant 6.) avoiding hazardous 7.) using lowest EDfor shortest time
Created by: Hoopster