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Derm 5 Bullous Dz

Bullous Diseases and Neoplasms

QuestionAnswer
Which sign is described and what disease is it a/w?: deep palpation of the RUQ-> arrest of inspiration due to back pain Murphy's sign: cholecystitis
Which sign is described and what disease is it a/w?: Charcot's triad (fever, jaundice, RUQ pain), hypotension, mental status changes Reynold's pentad: Cholangitis
Which sign is described and what disease is it a/w?: RLQ pain on passive extension of the hip Psoas sign: appendicitis
Which sign is described and what disease is it a/w?: RLQ pain on passive internal rotation of the flexed hip obturator sign: appendicitis
Which sign is described and what disease is it a/w?: LUQ pain and referred L shoulder pain Kehr's sign: splenic rupture
Which sign is described and what disease is it a/w?: ecchymosis of the skin overlying the flank Grey-Turner's sign: pancreatitis
Which sign is described and what disease is it a/w?: ecchymosis of hte skin overlying the periumbilical area Cullen's sign: pancreatitis
What is the tx for RSV bronchiolitis? Racemic epi or albuterol +/- supplemental O2
WHat is Beck's triad? When is it seen? Hypotension, distended neck vv, and distant heart sounds. Seen in cardiac tamponade
What is the prognosis of untreated pemphigus vulgaris? Fatal if untreated
What is the difference in treatment between pemphigus vulgaris and bullous pemphigoid? Pem vulgaris responds better to high dose systemic steroids whereas bullous pem responds better to topical steroids
What is the classic presentation of porphyria cutanea tarda? Chronic blistering on skin-exposed areas, hyperpigmentation and hypertrichosis on face, cutaneous thickening/scarring.
Who is the typical porphyria cutanea tarda pt? Alcoholic or Hep C pt
From the presentation, how might pemphigus vulgaris be distinguishable from bullous pemphigoid? Think of Gus Gus the fat mouse from Cinderella. pemphiGUS has flaccid/flabby blisters that are easy to pop/slough off= + Nikolsky. Gus likes to eat, so pemphiGUS has oral ulcers. Bullous pemphigoid has tense blisters, -Nikolsky sign, and rare oral ulcers.
What do the Ab target in bullous pemphigoid? BM (B for Bullous, B for Basement); hemidesmosomes.
What do the Ab target in pemphigus vulgaris? Epidermal adhesion molecules; desmosomes.
Which type of melanoma matches the following description?: MC type of melanoma supf spreading
Which type of melanoma matches the following description?: non-pigmented melanoma amelanotic
Which type of melanoma matches the following description?: dark papule on the legs or trunk that bleeds with minor trauma nodular
Which type of melanoma matches the following description?: occurs on palms, soles, or beneath nail plate in pts w/dark skin acrolentiginous
Which type of melanoma matches the following description?: dark lesion larger than 6mm wiht irregular, asymmetric borders supf spreading
What is the most important prognostic indicator in cases of melanoma? Depth/thickness of lesion. THis is why you NEVER do a shave bx! Must do a punch bx.
What are the tx options for actinic keratosis? 5-FU cream, cryotherapy, imiquimod
What is the classic appearance of BCC? Pearly papule with rolled edges and central ulceration with telangiectasias
What is the classic appearance of SCC? Papule or ulcer with irregular borders, scaling or keratotic. May have bleeding. May be painful or painless.
Created by: sarah3148
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