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MS 6 Other Rheum
Other Rheumatologic Diseases
Question | Answer |
---|---|
What happens to the platelet ct, bleeding time, PT, and PTT in HUS/TTP? | Dec platelet ct, incr bleeding time, norm PT and PTT |
What happens to the platelet ct, bleeding time, PT, and PTT in hemophilia A or B? | norm plt ct, norm bleeding time, normal PT, incr PTT |
What happens to the platelet ct, bleeding time, PT, and PTT in von Willebrand dz? | norm plt ct, incr bleeding time, norm PT, incr PTT (a/w factor 8) |
What happens to the platelet ct, bleeding time, PT, and PTT in DIC? | dec plt ct, incr bleeding time, increased PT/PTT |
What happens to the platelet ct, bleeding time, PT, and PTT in warfarin use? | norm plt ct, norm bleeding time, incr PT/PTT |
What happens to the platelet ct, bleeding time, PT, and PTT in end stage liver dz? | norm or dec plt ct, norm or incr bleeding time, incr PT/PTT |
What happens to the platelet ct, bleeding time, PT, and PTT in aspirin use? | norm plt ct, incr bleeding time (plt not as f'nl), norm PT/PTT |
What type of acute renal failure would you suspect in a pt with FENa<1%? | prerenal ARF (loss of volume) |
A pt presents with acute-onset monoarticular joint pain and Bell's palsy. What is the likely dx, how did he get it, and what is the tx? | Lyme dz. Ixodes tick. Tx w/doxy |
A 65yo AA woman is evaluated for weakness. THe pt has been an active person but now has weakness in her LE. On exam both are equally weak. She also has a rash on the chest. What labs would be helpful to order initially? | Dx= dermatomyositis. 1st order CK, aldolase, AST/ALT, and LDH. Also order ANA, Anti-Jo Ab, BMP, and CBC. |
Describe the rashes a/w dermatomyositis. | Periorbital heliotrope rash, malar rash on cheeks, shal sign, V sign (upper anterior chest), Gottron's papules, mechanics hands |
A 67yo woman complains of pain in her extremities, especially in the shoulders and hips. It is hard for her to even get out of bed. ESR is markedly elevated. What is the treatment? | Low-dose corticosteroids. Dx is polymyalgia rheumatica (PMR). |
What serious dz must you look out for in pts with polymyalgia rheumatica? | Temporal arteritis |
What does CREST stand for? | Calcinosis, Raynaud, esophageal dysmotility, Sclerodactyly, Telangiectasias |
Which rheum dz matches the following description?: proximal m weakness and facial rash | dermatomyositis |
Which rheum dz matches the following description?: pain and stiffness in the hips and shoulders | polymyalgia rheumatica |
Which rheum dz matches the following description?: muscle pain and tenderness in multiple distinct locations | fibromyalgia |
Which rheum dz matches the following description?: man in his 20s with low back pain that improves with exercise | ankylosing spondylitis |
Which rheum dz matches the following description?: jaw claudication and difficulty standing from a chair | PMR with temporal arteritis |
Which rheum dz matches the following description?: pencil0in-cup deformities of the DIP and PIP joints | psoriatic arthritis |
Which rheum dz matches the following description?: babmoo spine on x-ray | ankylosing spondylitis |
Which rheum dz matches the following description?: arthritis + oral ulcers + proteinuria | SLE |
What are the seronegative HLA-B27 spondyloarthropathies? | PAIR: Psoriatic arthritis, Ankylosing spondylitis, IBD, and Reactive Arthritis |
Which medications are FDA-approved for the tx of fibromyalgia? | Pregabalin, duloxetine (SRNI), and milnacipram |
WHat disease is a/w each of hte following serologic markers?: anti-Scl-70/topoisomerase | scleroderma |
WHat disease is a/w each of hte following serologic markers?: anti-Ro (anti-SSA), anti-La (anti-SSB) | Sjogren's syndrome |
WHat disease is a/w each of hte following serologic markers?: anti-histone Ab | drug-induced lupus |
WHat disease is a/w each of hte following serologic markers?: anti-Jo 1 antibodies | Polymyositis, dermatomyositis |
WHat disease is a/w each of hte following serologic markers?: anti-RNP | mixed CT d/o |