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Heme/Onc 9 Tx & Peds
Oncologic Therapy and Pediatric Heme-Onc
| Question | Answer |
|---|---|
| What is the definition of maternal mortality? | # of deaths from pregnancy to 42d post-partum per 100,000 live births |
| WHich type of lung cancer is a/w the following paraneoplastic syndrome? elevated ACTH-> glucocorticoid excess-> Cushing syndrome | small cell CA |
| WHich type of lung cancer is a/w the following paraneoplastic syndrome? elevated PTH related peptide-> hypercalcemia | SCC |
| WHich type of lung cancer is a/w the following paraneoplastic syndrome? elevated ADH-> SIADH-> hyponatremia | small cell CA |
| WHich type of lung cancer is a/w the following paraneoplastic syndrome? Ab to presynaptic Ca channels-> Lambert-Eaton syndrome | small cell CA |
| What dz causes glomerulonephritis with deafness? | Alport syndrome |
| Indications for using rhogam? | Give RhoGAM (RhoD Ig) within 72h of delivery of initial Rh+ fetus or at any time maternal and fetal blood may have mixed. |
| AR d/o a/w bone marrow failure, pancytopenia, short stature, abnorm skin pigmentation, horseshoe kidney, and thumb abnormalities. Dx? Increased risk of developing what? | Fanconi anemia. Incr risk of developing leukemia |
| Congenital pure RBC anemia a/w fatigue, dyspnea, cyanosis, pallor, craniofacial abnormalities, thumb abnormalities, heart murmurs, MR, and hypogonadism. Dx? Tx? | Diamond-Blackfan anemia. Tx with transfusions, corticosteroids, and bone marrow transplant |
| Abdominal distention and pain in a child with weight loss, malaise, bone pain, diarrhea, abdominal mass, and HTN. Dx? What syndrome may they have? | Neuroblastoma. May present with Horner's syndrome |
| How do you differentiate neuroblastoma from Wilms tumor? | Wilms has hematuria but Neuroblastoma does not. |
| A 5yo boy is brought in with a swollen leg. The child has not had any recent trauma. The swollen area actually is a mass that seems imbedded within hte vastus medius of the R thigh. What is the next step in the mgmt? | CT or MRI to determine extent. Bx later. |
| What is the MC adrenal tumor in children? What lab studies can be used to diagnose this? | Neuroblastoma. VMA and homovanillic acid. |
| A 4yo girl is brought into county clinic with a URI. Mother reports child seems to get sick more than her friends. PE is remarkable for dangling thumbs, short stature, and hypopigmentation of some skin areas. Labs reveal pancytopenia. Likely dx? | Fanconi's anemia |
| 3mo old child brought to office w/difficulty breathing, fatiuge, and pallor. He has a murmur and abnormal thumbs. Labs: Hgb/Hct 4/12%, WBC 8,000, platelets 300,000, MCV 99. Dx? What would you expect the level of erythropoietin to be? | Diamond-Blackfan anemia. Increase EPO. |
Created by:
sarah3148