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QuestionAnswer
I. Structure of glands
Development Epithelium tissue penetrates into the underlying tissue and forms a exocrine gland
Gland structure 2 parts parenchyma, stoma
1. Parenchyma secretory ducts
2. Stroma connective tissue
II. Secretory products of epithelia
Made intacellularly by macromolecular synthesis
Stored in vesicles called secretory granules
III. Two Major groups of glands classified by method of distribution
Exocrine (exits)secrete products via ducts
Endocrine (d for duckless)ductless, secrete directly into blood or lymphatic vesseles
Products Stored in parenchymal cells
Secrete peptide, proteins, steroids
Both exo/endo glands are pancrease ovary and testes
Endocrine Glands(duckless)
Thyriod store its secretory substance in the lumina of follicles
When hormones need to be released they are endocytosed and cleaved by lysosomes
Suprarenal glands secretory cells are arranged around capillaries
Hormone is stored intracellularly and released with signal
Pancrease both exo and endo secretions
Endocrine cells are called Islets of langerhans
Exocrine cells are acini
Pituitary ??
IV. Signaling Molecules
Cytokines act on specific target cells with receptors
Autocrine (asexual itself) acts on itself
Paracrine (proxy nearby)acts on cells in vicinity
Endocrine acts on cells far away
V. Secretory pathways
Constitutive (continuous) continuous release of secretory prodcuts
Regulated concentrated and stored molecules are released only after signal is received
VI. Classifications exocrine glands based on TYPE of secretion
Three types of exocrine glands mucous, serous, mixed
1. Mucous glands lubricant called mucin (mucus)
Has goblet cells and salivary
2. Serous glands enzyme rich watery fluid (from pancreas)
3. Mixed both mucous and serous
Ex submandibular salivary glands have BOTH
VII. Classification based on MODE of secretion
Holocrine (hail disintergrates)cells disintegrate and release contents
Merocrine cell release by exocytosis (parotid gland)
Apocrine (Ap apinch)secretes by pinching off portion of cell (lactating)
VIII. Morphological of Exocrine glands
1. Unicellular simplest
Goblet cells found in digestive and respiratory epithelium and protects epithelial lining
2. Multicellular clusters of cells
Simple do not branch
Complex/Compound ducts branch and look like clovers
IX. Brief description
Sweat glands simple coiled tubular glands, duct traverses the dermis and epidermis to open as a sweat pore
Subaceous glands appendages of hair follicles that secrete a waxy product to coat hair shaft and skin
X. Salivary glands
1. Myoepithelial cells (basket cells) surround the secretary cell
Rich in actin and myosin
They contract to help release of secretory product into ducts
2. Intercalated duct cuboidal epithelium
Excretory ducts stratified cubiodal and changes to columnar
Main duct stratified squamous epithelium, empties to oral cavity
3. Intralobular(striated duct) radial striations, and ion transport
Created by: mcap
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