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Antiemetic and Antinausea

H1 Receptor Blockers dimenhydrinate (Dramamine) diphenhydramine (Benadryl)
Antidopaminergic Drugs prochlorperazine (Compazine) NV promethazine (Phenergan) NV
Prokinetic Drugs metoclopramide (Reglan) Long-term use may cause irreversible tardive dyskinesia Black label drug due to extrapyramidal defects
Serotonin Blockers Used for nausea and vomiting in patients receiving chemotherapy and for postoperative nausea and vomiting odansetron (Zofran)
Tetrahydrocannabinoids Major psychoactive substance in marijuana Used for nausea and vomiting associated with chemotherapy, and anorexia associated with weight loss in AIDS patients
Teaching Educate about the possible adverse effects of ondansetron, including headache, which may be relieved by taking a simple analgesic (e.g., acetaminophen).
Teaching Antiemetics are often given 30 to 60 minutes before a chemotherapy drug is administered (time may vary depending on the specific drug) and may also be given during the chemotherapeutic treatment.
Created by: codzep