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GI PP 2
Antiemetic and Antinausea
| Question | Answer |
|---|---|
| H1 Receptor Blockers | dimenhydrinate (Dramamine) diphenhydramine (Benadryl) |
| Antidopaminergic Drugs | prochlorperazine (Compazine) NV promethazine (Phenergan) NV |
| Prokinetic Drugs | metoclopramide (Reglan) Long-term use may cause irreversible tardive dyskinesia Black label drug due to extrapyramidal defects |
| Serotonin Blockers | Used for nausea and vomiting in patients receiving chemotherapy and for postoperative nausea and vomiting odansetron (Zofran) |
| Tetrahydrocannabinoids | Major psychoactive substance in marijuana Used for nausea and vomiting associated with chemotherapy, and anorexia associated with weight loss in AIDS patients |
| Teaching | Educate about the possible adverse effects of ondansetron, including headache, which may be relieved by taking a simple analgesic (e.g., acetaminophen). |
| Teaching | Antiemetics are often given 30 to 60 minutes before a chemotherapy drug is administered (time may vary depending on the specific drug) and may also be given during the chemotherapeutic treatment. |