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Herpesviridae Ch. 24
| Question | Answer |
|---|---|
| Which family of DNA viruses is the most prevalent and causes the most disease? | Herpesviridae |
| What is the likelihood that you have been infected with a herpes virus? | pretty high |
| What are the 3 herpes viruses with which you have most likely been infected? | 1,2,3 |
| Most herpes viruses can remain ___________for long periods of time and reactivate later. | latent |
| Herpes viruses are assigned numbers based on __________. | order in which they were discovered |
| HHV-1 also called Herpes ______________ is usually associated with ________________. | simplex virus, children |
| HHV-2 also is usually associated with _____________ herpes. | genital |
| HHV around the mouth is known as ___________ herpes. | oral |
| HHV on a finger is known as ________________. | whitlow |
| HHV around the eyes is known as ___________herpes | ocular |
| How does HHV1 or HHV-2 enter the body? | through cracks or cuts in mucous membranes |
| HHV spreads from cell to cell through _______. | syncytia formation |
| If the HHV-1 or HHV-2 cross the placenta they cause __________ herpes, which can be very debilitating for a fetus. | neonatal |
| Varicella-zoster is caused by HHV-__________. | 3 |
| The common name for HHV-3 is ____________________. | Varicella-Zoster Virus |
| A sequel to HHV-3 is _________ or _______ zoster. | Varicella, Herpes |
| Shingles is a painful _________ that occurs at the distal end of a sensory _____. | rash; nerve |
| The sections of skin associated with shingles are called ________. | dermatones |
| A ______________ is available to adults over 60 to help prevent shingles. | vaccine |
| HHV-4 is also known as ______________ ____________ virus. | Epstein-Barr Virus |
| HHV-4 enters the body via the ______________ or ________________ gland. | parotid and salivary |
| HHV-4 ultimately invades the ______ lymphocytes. | B |
| B cells infected with HHV-4 become ________ and ____________ apoptosis (programed cell death). | latent; suppress |
| A “civil war” erupts between the ________ and _________ branches of the specific immune system. | humoral and cellular |
| Infectious ________ and chronic ________ syndrome are associated with HHV-4. | mononucleosis; fatigue |
| The first virus shown to be carcinogenic was a HHV-4 virus known as ____________________, a malignant, infectious neoplasm of the jaw. | Burkitt's lymphoma |
| HHV-4 is shed in an infected persons _________. | mouth |
| HHV-5 is known as ________. | Cytomegalovirus |
| What is the likelihood that you have been infected with HHV-5? | 50% |
| The transmission route for CMV is ______________. | through bodily secretions |
| If HHV-5 (CMV) infects stem cells it is _________, causing birth defects. | teratogenic |
| A diagnostic tool for CMV is detection of inclusions in cells that resemble an ___________. | owl's eye |
| HHV-6 is also known as ______________. | Roseolovirus |
| HHV-6 is characterized by fever, a faint pink _____, sore ______ and enlarged ______nodes. | rash; throat; lymph |
| HHV-8 is associated with _______ , a condition associated with AIDS. | Kaposi’s sarcoma |