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Drugs, Fred's way 05
Adenosine, Aspirin, D50, Diazepam, Vasopressin
Question | Class | Concentration | Amt Carried | MOA | Effects | Indications | Dose | Side Effects |
---|---|---|---|---|---|---|---|---|
Dextrose 50% (D50) | Carbohydrate, Hyperglycemic | 25grams/50mL prefilled syringe | 50 grams | Pharmacological - Aerobic metabolic substrate; increases blood sugar levels | Reverses CNS effects of hypoglycemia by rapidly increasing serum glucose levels. Provides short-term osmotic diuresis | Known hypoglycemia, ALOC of unknown etiology, post seizure activity with hypoglycemia | 12.5 - 50 grams IV bolus; consider giving thiamine with D50 | will cause tissue necrosis if extravasation occurs |
Diazepam (Valium) | Benzodiazepine | 10mg/2mL | 20 mg | Enhances GABA in the brain; causes muscle relaxation; suppresses CNS | Decreases seizures by increasing seizure threshold, analgesia, amnesic, sedation | Status epilepticus, delirium tremons, transient analgesic/amnesia for medical procedures | 2mg increments slow IVP. No faster than 5mg/min. Status - 5-10mg IVP q 10-15 min to total of 30mg. Cardioversion - 5-15mg over 5-10 min prior to cardioversion; can sclerose blood vessels if pushed too fast | Respiratory depression, hypotension, drowsiness, may increase seizures after stopping long term use |
Vasopressin | Pituitary hormone; Antidiuretic hormone | 40 Units | Optional | Vasoconstriction of peripheral, cerebral, pulmonary & coronary vessels | Pressor effects; increases diastolic pressure | Adult shock - refractory; V-Fib/Pulseless V-Tach | 40U one time only prior to epi. May replace 1st or 2nd dose of Epi in code | will constrict cerebral vasculature at doses over 40U |
Adenosine (Adenocard) | Antiarrhythmic, endogenous nucleoside | 6mg/2mL | 5-6 vials | Slows conduction of electric impulse through SA and AV node. Hyperpolarizes cell membrane | Slows sinus rate, can interrupt re-entry pathway | Conversion of stable SVT with no known A-Fib or A-Flutter; wide complex tachycardia suspicious of SVT | 6mg rapid IVP over 1-3 seconds chased with 20mL NS. May repeat at 12mg twice if no response in 1-2 min after initial dose. | Bradycardia,chest pain |
Acetylsalicylic Acid (Aspirin, Bufferin) | Nonsteroidal antiinflammatory Drug (NSAID) | 81mg tablets | 36-100 tablets | Decreases platelet aggregation; vasoconstriction; Blocks thromboxane A2 | Decreases blood clotting by preventing platelets from sticking together. Thins the blood; decreases inflammation in the lumen/tunica intima of blood vessels | Chest pain, other signs or symptoms of acute myocardial infarction | 160-324 mg chewed PO | may cause GI bleed with prolonged use |