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Drugs, Fred's way 05

Adenosine, Aspirin, D50, Diazepam, Vasopressin

QuestionClassConcentrationAmt CarriedMOAEffectsIndicationsDoseSide Effects
Dextrose 50% (D50) Carbohydrate, Hyperglycemic 25grams/50mL prefilled syringe 50 grams Pharmacological - Aerobic metabolic substrate; increases blood sugar levels Reverses CNS effects of hypoglycemia by rapidly increasing serum glucose levels. Provides short-term osmotic diuresis Known hypoglycemia, ALOC of unknown etiology, post seizure activity with hypoglycemia 12.5 - 50 grams IV bolus; consider giving thiamine with D50 will cause tissue necrosis if extravasation occurs
Diazepam (Valium) Benzodiazepine 10mg/2mL 20 mg Enhances GABA in the brain; causes muscle relaxation; suppresses CNS Decreases seizures by increasing seizure threshold, analgesia, amnesic, sedation Status epilepticus, delirium tremons, transient analgesic/amnesia for medical procedures 2mg increments slow IVP. No faster than 5mg/min. Status - 5-10mg IVP q 10-15 min to total of 30mg. Cardioversion - 5-15mg over 5-10 min prior to cardioversion; can sclerose blood vessels if pushed too fast Respiratory depression, hypotension, drowsiness, may increase seizures after stopping long term use
Vasopressin Pituitary hormone; Antidiuretic hormone 40 Units Optional Vasoconstriction of peripheral, cerebral, pulmonary & coronary vessels Pressor effects; increases diastolic pressure Adult shock - refractory; V-Fib/Pulseless V-Tach 40U one time only prior to epi. May replace 1st or 2nd dose of Epi in code will constrict cerebral vasculature at doses over 40U
Adenosine (Adenocard) Antiarrhythmic, endogenous nucleoside 6mg/2mL 5-6 vials Slows conduction of electric impulse through SA and AV node. Hyperpolarizes cell membrane Slows sinus rate, can interrupt re-entry pathway Conversion of stable SVT with no known A-Fib or A-Flutter; wide complex tachycardia suspicious of SVT 6mg rapid IVP over 1-3 seconds chased with 20mL NS. May repeat at 12mg twice if no response in 1-2 min after initial dose. Bradycardia,chest pain
Acetylsalicylic Acid (Aspirin, Bufferin) Nonsteroidal antiinflammatory Drug (NSAID) 81mg tablets 36-100 tablets Decreases platelet aggregation; vasoconstriction; Blocks thromboxane A2 Decreases blood clotting by preventing platelets from sticking together. Thins the blood; decreases inflammation in the lumen/tunica intima of blood vessels Chest pain, other signs or symptoms of acute myocardial infarction 160-324 mg chewed PO may cause GI bleed with prolonged use
Created by: whitefire70