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Paramedic:MOA's

MOA's

QuestionAnswer
Oxygen Increases arterial o2 tension and hemoglobin saturation,transported by hemoglobin,and enables cells to break down glucose
Epinephrine (1:10,000) catecholamine that stimulates alpha and beta adrenergic receptors
Dopamine (inotropin) Catecholamine that stimulates dopaminergic,beta and alpha adrenergic receptors,natural precurser of nor-epi
Norepinephrine (levophed) alpha 1 stim and beta 1 stim-predominantly Alpha 1 stimulating
Vasopressin non-adrenergic vasoconstrictor,increases perfusion and o2 delivery,and V-fib frequency
Propranolol (inderal) Blocks beta 1 and beta 2 receptors,decreases renin from the kidneys
Metoprolol (lopressor) decreases HR,CO,SBP and reflex tachy,antagonizes catecholamines
Atenolol (tenormin) blocks stim of beta1,doesnt effect beta 2,decreases HR,O2 consumption,decreases renin-aldosterone, angiotensin system at high doses
Lidocaine (xylocaine) Blocks fast sodium channels leading to decreased automaticity,shortens repolarization times,raises v-fib threshold,decreases conduction velocity
Procainamide (pronestyl) Blocks slow sodium channels leading to decreased automaticity (atrial),blocks fast sodium channels to decrease muscle depolarization (ventricles),prolongs repolarization times,produces peripheral vasodilation,increases v-fib threshold
Amiodarone (cordaron) acts on all cardiac tissue,blocks Na+,Ca++,K+ amd alpha and beta receptors,which prolongs action potential and refractory period,decreases automaticity/conductivity/and contractility,relaxes coronary and vascular smooth muscle
Magnesium sulfate (cardiac) CNS depressant,reduces the release of ACh by motor nerves so seizure activity is decreased,slows HR,causes peripheral vasodilation,stabilizes cell membranes, necessary for Na+/K+ pump function
Adenosine (adenocard) decreases conduction of electrical impulse through the AV node,interupts AV re-entry pathways,slows sinus rate
Calcium chloride increases myocardial contractility and ventricular automaticity,necessary for transmission of nerve impulses,contraction of all muscle,renal function,blood clotting,regulation of hormones and mainting integrity of cell membranes
Verapamil (isoptin,calan) Inhibits movement of calcium ions across cell membranes during depolarization,decreases afterload,dilation of arterioles and coronary arteries,slows SA and AV conduction,decreases O2 requirements,may cause heart blocks
Diltiazem (cardiazem) Inhibits calcium ion influx during depolarizations,decreases B/P,angina,supresses arrhythmias,relazes coronary vasculature,slows SA/AV conduction times
Atropine Sulfate Inhibits action of acetylcholine,increases automaticity,conduction,HR and CO,will reduce organophosphate overdose (sludge),relaxes bronchial smooth muscle,dilates pupils
Digoxin (lanoxin) Inhibits Na+/K+ pump,increases inotropic effect(contractility),vagal tone,and CO,negative chronotropic effects
Aspirin decreases pain and fever,platelet inhibitor,vasodilation,decreased clot formation,reduses inflammation
Retaplase (retavase) Converts endogenous plasminogen to plasmin,plasmin then degrades the fibrin of the thrombus=clot breaks up
Sodium bicarbonate Neutralizes excess acid,raises the pH in the serum and urine so drugs can be excreted more rapidly,encourages redistribution of K+ from extracellular to intracellular fluids,electrolyte replacement
Morphine sulfate CNS depressant,inhibits pain perception,decreases emotional response,causes sedation,decreases preload(venous dilation,decreases afterload (arteriole dilation)-more venous then arteriole
Fentanyl (sublimaze) Inhibits ascending pain pathways in CNS, increases pain threshold, and alters pain perception by binding to opiate receptors
Nitrous oxide Depresses CNS causing anesthesia,reduces hypoxia
furosemide (lasix) causes rapid diuresis,venodilation (reduced preload),decreases renal vascular resistance,excretion of Na+,Cl-,K+,H+,Ca++,Mg++,HCO-3, may cause elctrolyte imbalances
Nitroglycerin (nitrostat) relaxes vascular smooth muscle promoting vasodilation,decreases preload/afterload,and O2 consuption,dilates pulmonary capillary beds
labetolol (trandate normodyne) alpha 1 blocking agent,vasodilates,decreased PVR,nonselective beta blocking agent,BP reduces without reflex tachy-more potent alpha blocker thean beta blocker
Albuterol (proventil) stimulates B2 receptors,minimal B1 stim,may cause tachy,promotes intracellular shift of K+ from serum,inhibits histamine release,increased diuresis
Methylprednisolone (solu-medrol) Supresses acute and chronic inflammation,potentiates vascular smooth muscle relation by beta adrenergic agonist
Dexamethasone (decadron) Supresses acute and chronic inflammation,relaxes vascular and bronchial smooth muscles by beta adrenergic agonists
Racemic Epinephrine (micro nefrin) bronchodilator that stimulates B2 receptors in the lungs,relaxes bronchial smooth muscle,inhibits the release of histasmine,useful in treating laryngeal edema
50% dextrose Increases blood glucose,provides calories,decreases rate of ketone production,osmotic diuretic
Thiamine Required for metabolic processes,important in carbohydrate metabolism,helps breakdown glucose
Glucagon exerts positive inotropic action on the heart which decreases renal vascular resistance,increases the breakdown of glycogen to glucose
Diazepam (valium) CNS depressant,relaxes skeletal and smooth muscle,anticonvulsant,decreases agitation,tremors and hallucinations
Magnesium Sulfate (non cardiac) CNS depressant,reduce the release of ACh by motor nerves to decrease seizures,slows HR,causes peripheral vasodilation,stabalizes cell membranes, necessary for Na+/K+ pump function
Activated Charcoal Binds to and absorbs ingested poisons,effective with ASA,amphetamines,strychnine,dilantin,theophylline and phenobarbital,absorbs enzymes,vitamins,minerals and nutrients from GI tract
Diphenhydramine (benadryl) reverses effects of phenothiazine tranquilizers (dystonic reactions),causes CNS depression,anticholinergic properties (blocks ACh),antimimetic, competes with histamine receptor sites
Naloxone (Narcan) Reverses effects of narcotics or synthetic narcotics,competes for and displaces narcotic molecules from opiate receptors in the brain,reverses stupor,coma,respiratory depression caused by opiates
Promethazine (phenergan) blocks the actions of histamine,sedative,anti motion,antimimetic and anticholinergic activity,often administered with analgesics,particularly narcotics to potentiate their effects
Created by: rebeccabelleth