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C9) Cancer

Division may be regulated by internal and external factors.

QuestionAnswer
Define nutrient dependence. The need for certain nutrients to be present in the extracellular environment which bathes the cell in order for cell division to occur.
Define anchorage dependence. The need for cells to be attached to a substrate in order to divide.
Define density dependence. Cells that will not divide if they are packed together with their membranes touching. Contact inhibition.
Define mitosis promoting factors. Protein complexes that trigger the cell to proceed from interphase into mitosis.
Define kinases. Proteins that are activated by MPF, and in addition to cyclins, are vital for mitosis to occur.
Define cyclins. Proteins, that, along with kinases, are vital for mitosis to occur.
Define growth factors. A group of chemicals, usually proteins which are involved in stimulating a cell to divide.
Describe platelet derived growth factor. One of the numerous growth factors, or proteins that regulate cell growth and division. In particular, it plays a significant role in blood vessel formation (angiogenesis), the growth of blood vessels from already-existing blood vessel tissue.
Describe nerve growth factors. A growth factor that promotes the proliferation of connective tissues.
Describe Interleukin 2 A growth factor that triggers the development of specific white blood cells as part of the immune response.
Define onco-genes. Genes which control the development of cancers in that they are responsible for the production of growth-promoting or growth inhibiting factors.
Define cancer. An abnormal growth of cells which invades other tissues and may move to other parts of the body.
Define carcinogen. Mutagens that increase the rate of cancer.
Give examples of carcinogens. Asbestos fibres, gases and particles in cigarette smoke, free-radicals.
Define benign. A growth that remains at its original site and is not generally life threatening unless it grows in a confined space (skull).
Define malignant. Cancerous growths that grow quickly and may split off and spread.
Define secondary tumours. Tumours that arise from the spreading of primary tumours.
Define metastasis. The splitting and spreading of cancer cells through the blood or lymph systems.
Define biopsy. The process of collecting cells from tumours and nearby lymph glands and testing them for malignancy.
Define carcinomas. Cancers that originate in the external or internal covering of the body such as the intestine and the skin or in glands such as the breast.
Define sarcomas. Cancers that arise in any connective tissues of the body such as bone, nerve, and muscle.
Define leukaemias and lympthomas. Cancers that arise in the tissues which form white blood cells such as lymph, spleen and bone marrow.
What are growth factors in plant cells called? Auxins
What are synthetic auxins useful for? Weedicides! They stimulate the cells of a plants to divide too rapidly, killing it.
Created by: MahaliaMcD
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