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UMB's Drug List

For P1 Students

GenericBrandCommon DoseTherapeutic ClassCommon IndicationsAbsolute ContraindiationsSide Effects
Penicillin VK Penicillin V Potassium 250mg BID, 500mg TID, 2-4g/day QID Antibiotic, Penicillin Treat bacterial infections Hypersensitivity to it N/V/D, rash, anaphylaxis, hemolytic anemia
Piperacillin & Tazobactam Zosyn IV: 3.375-4.5g q4-8 hrs Antibiotic, Penicillin Treat bacterial infections Hypersensitivity to it, other penicillins, other beta lactamase inhibitors N/V/D, rash, anaphylaxis, headache, fever, insomnia, agitation, edema, constipation, pain, oral candidiasis, cardiac problems
Azithromycin Azasite, Zithromax, Zmax 1 gtt/eye BID x 2 days, 1 gtt SID x 5 days, 500mg SID 1-3 days, then 250mg SID x 4 days; some 1-2g once Antibiotic, Macrolide, Ophthalmic Treat bacterial infections, bacterial conjunctivitis Hypersensitivity to it, other macrolides N/V/D, rash, anaphylaxis, headache, abdominal pain, hepatotoxicity, myasthenic crisis
Clarithromycin Biaxin 250-500mg BID, 1000mg SID x 7-14 days Antibiotic, Macrolide Treat bacterial infections Hypersensitivity to it, other macrolides, co-administration with ergot derivatives N/V/D, anaphylaxis, headache, abdominal pain, indigestion, abnormal taste, S-J syndrome, toxic epidermal necrolysis, hepatitis, liver failure
Ciprofloxacin Ciloxan, Cetraxal, Cipro, Proquin Ophthalmic: 1-2 gtt q2 hrs x 24 hrs, then 1-2 gtt q4 hrs; Otic: 0.25mg BID x 7 days; Oral/IV: 400-750mg q12 hrs x 3 days-6 weeks Antibiotic, Quinolone, Opthalmic, Otic Treat bacterial infections Hypersensitivity to it, other quinolones, co-administration with tizanidine N/V/D, anaphylaxis, S-J syndrome, toxic epidermal necrolysis, tendinitis, tendon rupture, aplastic or hemolytic anemia, bone marrow depression, peripheral neuropathy, dizziness, restlessness, seizure, psychosis, acute renal failure, burning/pain in eye
Levofloxacin Levaquin, Quixin, Iquix 500-750mg SID x3-60 days; 1-2 gtt q30 min-2 hrs x 1-3 days, then 1-2 gtt q1-4 hrs x 4-5 days Antibiotic, Quinolone, Respiratory Fluoroquinolone Treat bacterial infections Hypersensitivity to it, other quinolones N/V/D, anaphylaxis, S-J syndrome, tendinitis, tendon rupture, anemia, headache, seizure, cardiac problems
Moxifloxacin Avelox, Vigamox 400mg q24 hrs x 4-14 days; Ophthalmic: 1 gtt/eye TID x 7 days Antibiotic, Quinolone, Ophthalmic, Resiratory Fluoroquinolone Treat bacterial infections Hypersensitivity to it, other quinolones N/V/D, anaphylaxis, S-J syndrome, tendinitis, tendon rupture, anemia, cardiac problems, dry eyes
Cefazolin Ancef, Kefzol IM/IV: 1-1.5g q8 hrs, max 12g/day Antibiotic, Cephalosporin, First Generation Treat bacterial infections Hypersensitivity to it, other cephalosporins Diarrhea, anaphylaxis, S-J syndrome, hepatotoxicity, seizure, pruritus, drug-induced eosinophilia, pseudomembranous enterocolitis, leukopenia, thrombocytopenia, encephalopathy
Ceftriaxone Rocephin IM/IV: 1-2g SID-BID Antibiotic, Cephalosporin, Third Generation Treat bacterial infections, Sx prophylaxis Hypersensitivity to it, other cephalosporins, hyperbilirubinemic neonates (esp. premature), concomitant use with IV Ca2+ solutions in neonates D/V, S-J syndrome, toxic epidermal necrolysis, erythema multiforme, hemolytic anemia, transient increased liver enzymes, immune hypersensitivity rxn, reversible disorder of gallbladder, kernicterus of newborn, kidney or lung finding
Cephalexin Keflex 250-1000mg q6 hrs, max 4g/day Antibiotic, Cephalosporin, First Generation Treat bacterial infections Hypersensitivity to it, other cephalosporins Diarrhea, abdominal pain, transient increased liver enzymes
Sulfamethoxazole & Trimethoprim Bactrim, Septra, Sulfatrim Based on trimethoprim: S800/T160mg q12-24 hrs; IV: 8-20mg TMP/kg/day q6-12 hrs Antibiotic, Msc/Sulfonamide derivative Treat bacterial infections Hypersensitivity to it, other sulfas, megaloblastic anemia due to folate deficiency, infants < 2 months of age, hepatic damage or renal disease, pregnancy at term, breastfeeding N/V, rash, anaphylaxis, S-J syndrome, toxic epidermal necrolysis, erythema multiforme, urticaria, aplastic anemia, thrombocyopenia, blood dyscrasia NOS, agranulocytosis, neutropenia, hepatic necrosis, clostridium difficile diarrhea
Doxycycline Adoxa, Doryx, Monodox, Oracea, Vibramycin 100-200mg/day SID-BID Antibiotic, Tetracycline derivative Treat bacterial infections, acne Hypersensitivity to it, other tetracyclines Photosensitivity, drug-induced GI disturbance, elevated serum blood urea nitrogen, bulging fontanelle
Clindamycin Cleocin, Clindagel, Clindamax, Evoclin 150-450mg q4-6 hrs, max 1.8g/day; IM/IV: 1.2-2.7g/day BID-QID, max 4.8g/day; Topical: SID-BID Antibiotic, Lincosamide, Topical skin product, Acne product Treat bacterial infections, acne Hypersensitivity to it, lincomycin, previous pseudomembranous colitis, regional enteritis, ulcerative colitis N/D, rash, pseudomembranous enterocolitis, elevated liver function test, jaundice
Metronidazole Flagyl 500-750mg q4-6 hrs, max 4g/day; IV: 1g loading dose Amoebicide, Antibiotic, Msc, Topical, Antiprotozoal, Nitroimidazole Treat bacterial infections, Protozoal infections Hypersensitivity to it, other nitroimidazole derivatives, first trimester pregnancy Nausea, S-J syndrome, toxic epidermal necrolysis, dizziness, headache, seizure, J-H rxn, candida infection of genitals, vaginal irritation or discharge, leukopenia, aseptic meningitis, encephalopathy, peripheral neuropathy, seizure, ototoxicity
Nitrofurantoin Furadantin, Macrobid, Macrodantin 50-100mg q6 hrs x 7 days; Macrobid 100mg BID x 7 days Antibiotic, Msc Treat urinary tract infections (UTIs) Hypersensitivity to it, renal imairment, < 1 month of age, pregnancy 38-42 weeks, previous Hx of cholestatic jaundice or hepatic impairment, Beers criteria N/V, hemolytic anemia, loss of appetite, cholestatic jaundice, hepatic necrosis, hepatitis, drug hypersensitivity syndrome, immune hypersensitivity rxn, interstitial lung dz, pulmonary fibrosis and toxicity, neuropathy
Rifampin Rifadin 10mg/kg/day, up to 600mg/day for 4 months Antibiotic, Msc, Antitubercular agent Manage active TB, eliminate meningococci Hypersensitivity to it, other rifamycins, concurrent use with amprenavir, saquinavir, ritonavir (other protease inhibitors) Discolored saliva, tears, or urine; loss of appetite, heartburn, nausea, sweat, influenza-like illness,thrombocytopenia, high-dose therapy, hepatotoxicity
Vancomycin Vancocin Oral: 500-2000mg/day q6 hrs; IV: 2-3g/day q8-12 hrs Glycopeptide Treat bacterial infections Hypersensitivity to it, use in patients with previous hearing loss from the medicine N/V, anaphylaxis, drug-induced erythroderma, neutropenia, drug hypersensitivity syndrome, ototoxicity, nephrotoxicity, thrombocytopenia
Fluconazole Diflucan 150mg once or 200-800mg/day Antifungal agent, Oral, Parenteral Treat candidiasis, fungal infections, prophylaxis for bone marrow transplants Hypersensitivity, cross reaction with other oral antifungals, concomitant administration with cisapride or terfenadine N/V, S-J syndrome, elevated liver enzymes, headache, torsades de pointes, seizure
Acyclovir Zovirax Oral: 200-800mg q4 hrs x 5 days-12 months; IV: 5-10mg/kg/dose q8hrs x 5-7 days; Topical: q3 hrs x 7 days Antiviral agent, Topical Treatment of HSV (genital), cold sores, herpes zoster (shingles) varicella zoster (chicken pox), HSV encephalitis, neonatal, mucocutaneous Hypersensitivity to it or valacyclovir N/V/D, application site rxn, contact dermatitis, S-J syndrome, toxic epidermal necrolysis, headache, malaise, thrombotic thrombocytopenic purpura, renal failure
Valacyclovir Valtrex 1-2g BID-QID x 3+ days Antiviral agent, Oral Treatment of herpes zoster (shingles), HSV (suppression, decrease transmission), immunocompetent and immunocompromised patients Hypersensitivity to it or acyclovir N/V, rash, abdominal pain, headache, thrombotic thrombocytopenic purpura, aseptic meningitis, encephalopathy, seizure, hemolytic uremic syndrome
Oseltamivir Tamiflu Prophylaxis: 74mg SID x 10 days; Treatment: 75mg BID x 5 days Antiviral agent, Neuraminidase inhibitor Treatment of acute illness, influenza A or B synptoms ≤ 2 days ≥ 1 year old, prophylaxis Hypersensitivity to it N/V, anaphylaxis, S-J syndrome, toxic epidermal necrolysis, erythema multiforme, facial swelling, abdominal pain, GI hemorrhage, hemorrhagic colitis, hepatitis, seizure, abnormal behavior, delirium
Acetaminophen Tylenol, Excedrin, Anacin, Cetafen 325-650mg q4-6 hrs, 1000mg TID-QID, max 4g/day Anagesic, Msc Treatment of mild to moderate pain, fever Hypersensitivity to it N/V, S-J syndrome, toxic epidermal necrolysis, pruritus, headache, insomnia, agitation, liver failure, atelectasis, pneumonitis, constipation
Aspirin Bayer, Ecotrin, St. Joseph's Initially 2.4-3.6g/day, max 5.4g/day; 325-650mg q4-6 hrs, max 4g/day Antiplatelet agent, Salicylate (NSAID warnings) Treatment of mild to moderate pain, inflammation, fever; Prevention/treatment of myocardial infarction, stroke, management of rheumatoid arthritis, rheumatic fever, osteoarthritis, gout (in high doses), heart Sx Hypersensitivity to it, other salicylates and NSAIDs, asthma, rhinitis, nasal polyps, bleeding disorders, children < 16 yrs of age, pregnancy (esp. 3rd trimester) GI ulcer, bleeding, tinnitus, bronchospasm, angioedema, Reye's syndrome
Ibuprofen Advil, Midol, Motrin 400-800mg TID-QID, max 3.2g/day NSAID, Oral, Parenteral Treatment of mild to moderate pain, inflammatory disease, rheumatoid disorders, dysmenorrhea, osteoarthritis Hypersensitivity to it, Hx of asthma, allergic type rxns to NSAIDs, aspirin triad (bronchial asthma, aspirin intolerance, rhinits), coronary artery bypass graft (CABG) Sx pain Rash, headache, S-J syndrome, toxic epidermal necrolysis, congestive heart failure, hypertension, myocardial infarction, bledding, anemia, heatitis, hepatotoxicity, liver failure, jaundice, acute renal failure, Reye's syndrome, GI problems
Naproxen Aleve, Midol [Extended Relief], Pamprin Initial dose of 500mg, then 250mg q6-8 hrs, max 1.25g/day NSAID Treatment of mild to moderate pain, management of ankylosing spondylitis, osteoarthritis, rheumatoid disorders, acute gout, tendonitis, bursitis, dysmenorrhea, fever Hypersensitivity to it, other NSAIDs, coronary artery bypass graft (CABG) Sx pain Rash, S-J syndrome, toxic epidermal necrolysis, edema, abd. pain, constpiation, heartburn, anemia, hepatitis, liver failure, jaundice, acute renal failure, nephritis, nephrotic syndrome, congestive heart failure, GI problems
Cetirizine Zyrtec, AllDay 5-10mg SID Histamine H1 antagonist, second generation Treatment of perennial and seasonal allergies Hypersensitivity to it, hydroxyzine Xerostomia, headache, somnolence, fatigue
Chlorpheniramine Ahist, Allerchlor, Chlorhist, Chlorphen, Teldrin 4mg q4-6 hrs, max 24mg/day Histamine H1 antagonist, first generation Perennial and seasonal allergies Hypersensitivity to it, narrow angle glaucoma, bladder neck obstruction, acute asthmatic attacks, premature/term newborns (associated with SIDS), Beers Criteria N/V/D, constipation, somnolence
Diphenhydramine Benadryl, Unisom 25-50mg q6-8 hrs, max 400mg/day Histamine H1 antagonist, first generation Allergy symptoms, anaphylaxis (when combined with epinephrine), night time sleep aid, prevention/treatment of motion sickness, antitussive, manage Parkinson's syndrome Hypersensitivity to it, acute asthma, neonates/preemies, breast feeding, local anaesthetic use (injection) Xerostomia, anaphylaxis, dizziness, dyskinesia, sedation, somnolence, dry nasal mucosa, pharyngeal dyness, thick bronchial sputum
Loratidine Claritin, Alavert, Tavist 10mg/day on an empty stomach Histamine H1 antagonist, second generation Nasal & non-nasal seasonal allergic rhinits, chronic idiopathic urticaria Hypersensitivty to it Xerostomia, headache, somnolence, fatigue, decreased liver function
Hydrocodone & Chlorpheniramine Tussionex, Tussicaps Capsule: 10mg/8mg (1 capsule) q12 hrs, max 2 caps/day; Liquid: 5mL q12 hrs, max 10mL/day Analgesic, Opioid, Antitussive, Histamine H1 antagonist, First generation Relief of cough and upper respiratory symptoms associated with cold and allergy Hypersensitivity, children < 6 yrs of age N/V, rash, chest tightness, anxiety, dizziness, drowsiness, dysphoria, euphoria, fear, sedation, psychological dependence, constipation, pruritus, ureteral spasm, urinary retention, vesicle sphincter spasm, dryness of pharynx, respiratory depression
Benzonatate Tessalon, Zonatuss 100mg TID-q4 hrs, max 600mg/day Antitussive Relief of nonproductive cough Hypersensitivty to it, related drugs Nausea, dizziness, headache, sedation, somnolence; If capsules are broken or chewed, numbness of tongue and throat and oral hypoaesthesia may occur
Dextromethorphan Delsym, Robitussin, Pediacare, Triaminic, Vicks 44, 12hr Cough Relief 10-20mg q4 hrs, 30mg q6-8 hrs; ER: 60mg BID, max 120mg/day Antitussive Treatment of cough caused by common cold or inhaled irritants Hypersensitivity, concurrent administration/use within 2 weeks of taking an MAOI Dizziness, somnolence, fatigue
Guafinesin Mucinex 200-400mg q4 hrs; ER: 600-1200mg q12 hrs, max 2.4g/day Expectorant Loosen phlegm and thin bronchial secretions Hypersensitivity to it N/V
Oxymetazoline Afrin, Duramist, 12hr Nasal Relief Opthalmic: 1-2gtt/eye q6 hrs prn; Nasal: 2-3 sprays each nostril BID x 3 days Adrenergic agonist agent, Imidazoline derivative, Vasoconstrictor, Nasal, Ophthalmic Treatment of nasal congestion, acute or chronic rhinitis, common cold, hay fever, allergies; Opthalmic: eye redness, minor irritants Hypersensitivity to it Headache, insomnia, nervousness, nasal congestion, rebound, dry nasal mucosa, stinging/burning in nostrils, sneezing, cardiac dysrhythmia, tachyarrhythmia, hypertension
Phenylephrine Afrin nasal mist, Pediacare, Sudafed Oral: 10-20mg q4 hrs (HCl), 10-20mg q12 hrs (tannate); Nasal: 1-2 sprays q4 hrs x 3 days; Hemorrhoids: QID Alpha/beta agonist, Opthalmic agent: Antiglaucoma, Mydriatic Treatment of nasal/nasopharyngeal mucosal congestion, relief of eye redness, treatment of hemorrhoids Hypersensitivity to it, hypertension, tachycardia, narrow-angle glaucoma, administration with or within 2 wks of an MAOI, use in newborns, while breastfeeding Hypertension, transient pain in eye, rebound nasal congegstion, stinging/burning in nostrils, sneezing, myocardial infarction, tachyarrhythmia, ventricular arrhythmia, pulmonary edema
Pseudoephedrine Sudafed 60mg q4-6 hrs, 120mg q12 hrs, 240mg q24 hrs, max 240mg/day Alpha/beta agonist Nasal congestion due to common cold, upper respiratory allergies, sinusitis, promotion of nasal or sinus discharge Hypersensitivity to it, use with or within 14 days of an MAOI, use in newborns, while breastfeeding Hypertension, tachyarrhythmia, insomnia, anxiety, nervousnes, restlessness, atrial fibrillation, myocardial infarction, premature ventricular contractions
Bisacodyl Dolcolax, Correctol, Biscolax, Ex-Lax 5-15mg single dose, 30mg for complete evacuation; take on empty stomach for rapid effect; do not use within 1 hr of ingesting dairy or antacids; Suppository: 10mg once Laxative, Stimulant Constpiation, colonic evacuation prior to procedures Hypersensitivity to it, abdominal pain or obstruction, nausea, vomiting, Beers Criteria Abdominal colic, abdominal discomfort, diarrhea, atony of colon; Suppository: proctitis
Senna Senokot, Black Draught, Sennagen, Fleet, Ex-Lax 12mg SID, upto 70-100mg/day BID, max 7 days. 130mg between 2-4pm day prior to exam (for colonic evacuation) Laxative, Stimulant Short term treatment of constipation, colonic evacuation Hypersensitivity to it, intenstinal obstruction, Crohn's disease, colitis ulcerosa, appendicitis, abdominal pain of unknown origin, pregnancy Abdominal pain, nausea, cramps, diarrhea, melanotic pigmentation of the colonic mucosa, electrolyte abnormalities, urine discoloration, nephritis, finger clubbing
Polyethylene Glycol Dulcolax balance, Miralax 17g (approx. 1 heaping Tbsp) dissolved in 4-8oz beverage SID up to 7 days (longer if directed) Laxative, Osmotic Treatment of occasional constipation in adults Hypersensitivity to it N/D, flatulence, stomach cramps, swollen abdomen
Docusate Colace, Correctol, Dolcolax, Fleet 50-500mg/day in 1-4 doses; 50-100mg in enema fluid Stool softener Constipation associated with hard and dry stools, prophylaxis for straining following myocardial infarction, patients who should avoid straining; doses < 200mg may be ineffective in long term treatment Hypersensitivity to it, concomitant use with mineral oil, intestinal obstruction, acute abdominal pain, nausea, vomiting N/D, cramping, bitter taste in mouth, hepatotoxicity
Loperamide Imodium, Diamode Initial dose of 4mg followed by 2mg after each loose stool, max 8-16mg/day depending on severity of diarrhea Antidiarrheal Treatment of chronic diarrhea associated with inflammatory bowel disease, acute nonspecific diarrhea, increased volume of ileostomy discharge Hypersensitivity to it, abdominal pain without diarrhea, use as primary therapy in acute dysentery, acute ulcerative colitis, bacterial enterocolitis, pseudomembranous colitis, children < 2 yrs of age N/D, abdominal pain, xerostomia, dizziness, somnolence, fatigue, hyperglycemia, necrotizing enterocolitis in fetus or newborn
Prednisolone Millipred, Omnipred, Orapred, Prelone, Veripred 5-60mg/day, titrated to lowest effective dose Corticosteroid, Opthalmic, Systemic Treatment of inflammation, inflammatory disorders, endocrine disorders Hypersensitivity to it, acute superficial herpes simplex keratitis, live or attenuated virus vaccines, systemic fungal or bacterial infections, varicella Edema, hypertension, acne, hyperflycemia, abnormal lipid count, muscle wasting, osteoporosis, cataracts, glaucoma, psychosis, congestiv heart failure, Cushing's disease, pseudotumor cerebri, seizures, Kaposi's sarcoma, diabetes mellitus
Albuterol inhaler (HFA) AccuNeb, ProAir HFA, Proventil HFA, Ventolin HFA, VoSpire ER Bronchospasm: 2 puffs q4-6 hr; Asthma: 4-8 puffs q20min for up to 4 hrs (patients < 12 yrs take 3 doses), then q1-4 hrs prn; Prevention of exercise-induced bronchospasm: 1-2 puffs 5-30 min prior to exercise Beta-2 agonist Treatment or prevention of bronchospasm in patients with reversible obstructive airway disease, prevention of exercise-induced bronchospasm Hypersensitivity to it Nausea, tachyarrhythmia, hypokalemia, pharyngitis, throat irritation, nervousness, headache, remor, cough, rhinitis, upeer respiratory infection, viral lower respiratory infection, atrial fibrillation, myocardial infarction, pulmonary edema
Salmeterol (Diskus) Serevent 1 inhalation BID Beta-2 agonist; Beta-2 adrenergic agonist, Long-acting Maintenance treatment of asthma; prevention of bronchospasm with reversible obstructive airway disease, including nocturnal asthma; prevention of exercise-induced bronchospasm; maintenance treatment of bronchospasm associated with COPD Hypersensitivity to it, must be used with asthma controller medication Headache, musculoskeletal pain, prolonged QT interval, exacerbation of asthma, asthma-related death
Fluticasone inhaler (HFA) Flovent Diskus, Flovent HFA 88-880mcg BID Corticosteroid, Inhalant (Oral) Maintenance treatment of asthma as prophylactic therapy; also indicated for patients requiring oral corticosteroid therapy for asthma to assist in total discontinuation or reduction of complete oral dose Hypersensitivity to it, primary treatment of status asthmaticus or acute bronchospasm Anaphylaxis, headache, bronchitis, cough, candidiasis of mouth and esohagus, epistaxis, inflammatory disorder of UR tract, sinusitis, throat irritation, UR infection, secondary hypocortisolism, immune hypersensitivity rxn, glaucoma, pneumonia
Mometasone nasal spray Nasonex 2 sprays/nostril SID-BID; < 12 yrs, 1 spray/nostril Corticosteroid, Nasal Treatment of nasal symptoms of seasonal and perennial allergic rhinitis; prevention of nasal symptoms associated with seasonal allergic rhinitis; treatment of nasal polyps in adults Hypersensitivity to it Anaphylaxis, headache, angioedema, aabdominal pain, indigestion, nausea, backache, musculoskeletal pain, myalgia, secondary hypocortisolism, candidiasis, epistaxis, pharyngitis, UR infection
Ipratropium inhaler (HFA) Atrovent HFA Acute asthma exacerbation: Nebulizer: 500mcg q20 min x 3 doses, then prn; MDI: 8 inhalations 120 min prn up to 3 hrs; COPD bronchospasm: Nebulizer: 500mcg TID-QID q6-8 hrs, MDI: 2 inhalations QID up to 12 inhalations/day; < 12 yrs use half to full dose Anticholinergic agent Anticholinergic bronchodilator used in bronchospasm associated with COPD, bronchitis, and emphysema Hypersensitivity to it, atropine, and derivatives Anaphylaxis, abnormal taste in mouth, xerostomia, nasal congestion, dry nasal mucosa, myocardial infarction, paralytic ileus, immune hypersensitivity rxn, angioedema, bronchospasm, urticaria, oropharyngeal edema, cerebrovascular accident
Tiotropium (Handihaler) Spiriva 1 capsule inhaled SID (two inhalations) Anticholinergic agent Maintenance treatment of bronchospasm associated with COPD, including bronchitis and emphysema; reduction of COPD exacerbations Hypersensitivity to it or ipratropium Constipation, xerostomia, pharyngitis, sinusitis, UR infection, bowel obstruction, cerebrovascular accident
Montelukast Singulair 10mg SID, 2 hrs before exercise; 2-5 yrs of age use 4mg SID, 6-14 yrs use 5mg SID Leukotriene receptor agonist Prophylactic and chronic treatment of asthma, relief of symptoms of seasonal and perrenial allergic rhinitis, prevention of exercise-induced bronchospasm Hypersensitivity to it Headache, allergic granulomatous angiitis, cholestatic hepatitis, aggressive or altered behavior, suicidal thoughts
Isotretinoin Amnesteem, Claravis, Sotret 0.5-2mg/kg/day BID x 15-20 weeks, or until acne decreases by 70% (whichever comes first); may be repeated after > 2 months off Acne product, Retinoic acid derivative Treat severe recalcitrant nodular acne unresponsive to conventional therapy Hypersensitivity to it, parabens, vitamin A, other retinoids, pregnancy Anaphylaxis, alopecia, cheilitis, dry skin, pruritus, retinoid dermatitis, xerostomia, arthralgia, conjunctivitis, epistaxis, elevated serum triglyceride, pancreatitis, neutropenia, hepatotoxicity, visual or hearing loss, aggressive behavior, depression
Hydrocortisone cream Cortaid, Cortizone-10, Dermarest, Locoid, HydroZone, Protocort, Texacort Topical: apply to affected area BID-QID; Rectal: 10-100mg SID-BID x 2-3 weeks Corticosteroid, Topical, Rectal Relief of inflammation of corticosteroid-responsive dermatoses (low to medium potency topical corticosteroids); adjunctive treatment of ulcerative colitis Hypersensitivity to it; Rectal: systemic fungal infection, ileocolostomy during the immediate or early post-operative period Atrophic condition of skin, impaired skin healing, GI tract disorder, osteoporosis, depression, Cushing's syndrome, drug-induced adrenocortical insufficiency, cataracts, glaucoma, hyperglycemia, immunosuppression
Terbinafine (topical) Lamisil Topical: apply to affected area SID x 1 week, max 4 weeks Topical antifungal agent Antifungal for treatment of tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm); tinea versicolor (prescription only) Hypersensitivity to it Diarrhea, headache, S-J syndrome, toxic epidermal necrolysis, erythema multiforme, agranulocytosis, neutropenic disorder, pancytopenia, cutaneous lupus erythematosus, systemic lupus erythematosus, liver failure
Brinzolamide (eye drops) Azopt 1 gtt in affected eye TID Carbonic anhydrase inhibitor, Opthalmic, Antiglaucoma Lowers intraocular pressure in patients with ocular hypertension or open-angle glaucoma Hypersensitivity to it or sulfonamides Headache, blurred vision, bitter taste in mouth, chest pain, immune hypersensitivity rxn
Ketotifen (eye drops) Alaway, Claritin Eye, Zaditor, Zyrtec Itchy Eye 1 gtt in affected eye BID-TID Histamine H1 antagonist, second generation; Mast cell stabilizer, Piperadine derivative Temporary relief of eye itching due to allergic conjunctivitis Hypersensitivity to it Headache, dry eyes, conjunctival eye irritation, pain in eye, pharyngitis, rhinitis, influenza
Latanoprost (eye drops) Xalatan 1 gtt in affected eye SID in evening Opthalmic agent, Antiglaucoma, Opthalmic prostaglandin Reduction of elevated intraocular pressure in patients with open-angle glaucoma orocularhypertension Hypersensitivity to it Blurred vision, eyelash follicle finding, hyperpigmentation of eyelid, iris pigmentation, macular retinal edema
Pimecrolimus Elidel Apply thin later to affected area BID Topical immunosuppressant Short term and intermittent long-term treatment of mild to moderate atopic dermatitis in patients unresponsive to conentional therapy, or when conventional therapy is not appropriate Hypersensitivity to it Burning sensation, increased risk of viral infection, headache, fever, basal cell carcinoma, malignant melanoma, squamous cell carcinoma, malignant lymphoma, septic arthritis
Timolol (eye drops) Betimol, Istalol, Timolol, Timoptic (0.25%): 1 gtt BID in affected eye; (0.5%): 1 gtt SID in AM, max 1 gtt BID Beta blocker, Nonselective, Opthalmic agent, Antiglaucoma Treatment of elevated intraocular pressure such as glaucoma or ocular hypertension Hypersensitivity to it, sinus bradycardia, sinus node dysfunction, heart block greater than first degree (except in patients with functional artificial pacemaker), cardiogenic shock, uncompensated cardiac failure, bronchospastic disease N/V/D, angina, bradyarrhythmia, heart failure, hypotension, pruritus, rash, urticaria, abdominal pain, indigestion, cramps, confusion, dizziness, headache, blurred vision, burning sensation, cataracts, dry eyes, cardiac dysrhythmia
Butalbital, Acetaminophen, & Caffeine Alagesis, Anolor, Dolgic, Esgic, Fioricet, Margesic, Orbian, Repan, Zebutal 1-2 tab/cap or 15-30mL q4 hrs, max 6 tabs/caps/180mL Barbiturate Relief of the symptomatic complex of tension or muscle contraction headache Hypersensitivity to it, porphyria N/V, abdominal pain, dizziness, sedation, somnolence, lightheadedness, dyspnea, erythema multiforme, toxic epidermal necrolysis, seizure
Hydrocodone & Acetaminophen Hycet, Lorcet, Lortab, Margesic, Maxidone, Norco, Stagesic, Vicodin, Xodol, Zamicet, Zydone Hydrocodone: 5-10mg QID Analgesic combination (Opioid) Relief of moderate to severe pain Hypersensitivity to it, CNS depression, severe respiratory depression N/V, dizziness, lightheadedness, sedation, agranulocytosis, thrombocytopenia, respiratory depression
Propoxyphene & Acetaminophen Balacet, Darvocet 1-2 tabs q4 hrs prn, max 390mg HCl or 600mg napsylate per day Analgesic combination (Opioid) Management of mild to moderate pain Hypersensitivity to it, severe asthma, hypercapnia, severe respiratory depression, paralytic ileus N/V, dizziness, sedation, electrocardiogram abnormalities, hypotension, papillary necrosis, respiratory depression
Codeine & Acetaminophen Tylenol with codeine Codeine: 15-60mg q4-6 hrs, max 360mg/day; max acetaminophen is 4g/day Analgesic, Opioid Relief of mild to moderate pain Hypersensitivity to it, acute/ severe asthma, hypercapnia, severe respiratory depression, paralytic ileus N/V, dizziness, lightheadedness, sedation, somnolence, agranulocytosis, thrombocytopenia, respiratory depression
Oxycodone Oxycontin, Roxicodone 5-20mg q4-6 hrs prn; CR: 10mg q12 hrs Analgesic, Opioid Management of moderate to severe pain, normally used in combination with nonopioid analgesics Hypersensitivity to it, acute/ severe asthma, hypercapnia, severe respiratory depression, paralytic ileus N/V, pruritus, sweating, constipation, xerostomia, asthenia, dizziness, somnolence, cardiac arrest, heart failure, hypotension, shock, immune hypersensitivity rxn, apnea, resppiratory arrest, respiratory depression
Tramadol Ultram, Rybix, Ryzolt 50-100mg q4-6hrs, max 400mg/day; ER: 100mg SID Analgesic, Opioid Relief of moderate to severe pain Hypersensitivity to it, Opioid dependency, acute intoxication with alcohol, hypnotics, centrally-acting analgesics, opioids, or psychotropic drugs N/V, constipation, xerostomia, dizziness, headache, insomnia, somnolence, myocardial infarction, flushing, pruritus, pancreatitis, anaphylactoid reaction, seizure, dyspnea, respiratory depression
Bismuth Bismatrol, Diotame, Kao-Tin, Kaopectate, Maalox, Pepto 524mg q30 min-1 hr, max 8 doses/day; 524mg QID w/meals, at bedtime (H. pylori) Antidiarrheal Subsalicylate formulation: symptomatic tx of mild, nonspecific diarrhea; control of traveler's diarrhea (E. coli); as part of multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence Hypersensitivity to it, subsalicylate formulation: children with viral fevers, hypersensitivity to salicylates, Hx of severe GI bleeding, Hx of coagulopathy, pregnancy in 3rd trimester N/V/D, constipation, grayish-black stool, tongue discoloration, neurotoxicity
Calcium Carbonate Alcalak, Alka-mints, Caltrate, Children's Pepto, Maalox, Florical, Nutralox, Tums, Mylanta 1-1.2g/day Antacid, Antidote Calcium salt, Electrolyte supplement, Oral Antacid, Tx and prevention of Ca2+ deficiency or hyperphosphatemia (osteoporosis, hypoarathyroidism, postmenopausal osteoporosis, rickets), bind phosphate Hypercalcemia, renal calculi, hypophosphatemia, patients with suspected digoxin toxicity N/V, headache, hypophosphatemia, hypercalcemia, constpiation, laxative effect, acid rebound, anorexia, abdominal pain, xerostomia, flatulence, milk-alkali syndrome (high chronic dose), renal failure
Carisoprodol Soma 250-350mg TID and at bedtime Skeletal muscle relaxant Short-term (2-3 week) Tx of acute musculoskeletal pain Hypersensitivity to it or meprobamate, acute intermittent porphyria, Beers Criteria Dizziness, headache, somnolence, seizure, drug abuse or dependence, withdrawal signs or symptoms
Cyclobenzaprine Amrix, Fexmid, Flexeril 5mg TID; ER: 15mg SID Skeletal muscle relaxant Treatment of muscle spasm associated with acute, painful musculoskeletal conditions Hypersensitivity to it, use with or within 12 days of taking an MAOI, hyperthyroidism, congestive heart failure, arrhythmias, heart block or conduction disturbances, acute recovery phase of MI, Beers Criteria Anaphylaxis, palpitations, bad taste, constipation, indigestion, nausea, pharyngeal dryness, xerostomia, asthenia, confusion, dizziness, headache, somnolence, blurred vision, feeling nervous, cardiac dysrhythmia, cholestasis, hepatitis, jaundice
Lactulose Constulose, Enulose, Generlac, Kristalose 10-30g (15-45mL) SID-QID; Rectal: 200g (300mL) with 700mL H2O; Ped: 0.7-60g (2.5-90mL) in divided doses/day Ammonium detoxicant, Osmotic laxative Prevention and treatment of portal-systemic encephalopathy (including hepatic precoma and coma), Tx constipation Use in patients requiring a low galactose diet N/V/D, bloating, flatulence, cram, epigastric pain, hypernatremia, hypokalemia
Ondansetron Zofran, Zuplenz 0.15mg/kg TID, 0.45mg/kg SID, 8-10mg SID-BID, 24-32mg SID Antiemetic, Selective 5-HT3 receptor antagonist Prevention of N/V associated with moderately to highly emetogenic cancer chemotherapy; radiotherapy; prevention of post-op N/V, Tx of post-op N/V if no prophylactice dose of ondansetron received Hypersensitivity to it, other 5-HT3 antagonists, concomitant use of apomorphine Anaphylaxis, diarrhea, constipation, increased liver enzymes, headache, fatigue, malaise, cardiac dysrhythmia, bronchospasm
Ketorolac Acular, Acuvail Oral: 20mg, then 10mg q4-6 hrs; Ophthalmic: 1 gtt QID x 4-14 days; IV: 30mg single or q6 hrs; IM: 60mg single, 30mg q6 hrs, max 120mg NSAID Oral/Injection: < 5 day management of moderate to severe acute pain requiring opioid analgesia; Ophthalmic: temporary relief of ocular itching due to seasonal allergic conjunctivitis, treatment of post-op symptoms from cataract or refractive Sx Hypersensitivity to it, other NSAIDs, Hx of peptic ulcer disease or GI bleeding/perforation, renal disease, concomitant use with probenecid or pentoxifylline, Beers Criteria Anaphylaxis, rash, edema, hypertension, S-J syndrome, toxic epidermal necrolysis, dizziness, headache, somnolence, pain, myocardial infarction, hepatitis, jaundice, liver failure, nephritis, GI bleeding/perforation, hemmorhaging
Celecoxib Celebrex 100-400mg/day SID-BID NSAID, COX-2 selective Relief of signs and symptoms of osteoarthritis, ankylosing spondylitis, rheumatoid arthritis, Tx of primary dysmenorrhea, reduction of intestinal polyps in familial adenomatous polyposis Hypersensitivity to it, other NSAIDs, sulfonamides, asirin, perioperative pain with CABG Sx N/D, anaphylaxis, hypertension, headache, MI, torsades de pointes, ventricular hypertrophy, erythema multiforme, erythroderma, S-J syndrome, toxic epidermal necrolysis, GI hemmorhage/perforation/ulcer, thromboses, hepatitis, liver failure
Cimetidine Tagamet 300mg QID, 800mg hs, 400mg BID up to 8 weeks, max 800mg BID up to 12 weeks; Heartburn relief: 200mg up to BID Histamine H2 antagonist Short term treatment of active duodenal ulcers and benign gastric ulcers; maintenance therapy of duodenal ulcers; treatment of gastric hypersecretory states; treatment of gastroesophageal reflux disease (GERD) Hypersensitivity to it, other H2 antagonists Gynecomastia, headache, necrotizing enterocolitis in fetus or newborn, agranulocytosis, leukopenia, seizure, psychotic disorder
Famotidine Pepcid, Heartburn relief Acute: 40mg hs, 20mg BID x 4-8 weeks; Maintenance: 20mg hs, up to 160mg q6 hrs; Children: 0.5mg/kg/day po, divided BID, max 40mg/day or BID depending on situation; OTC: > 12 yrs old Histamine H2 antagonist Maintenance therapy and treatment of duodenal ulcer; treatment of gastroesophageal reflux disease (GERD), active benign gastric ulcer, pathological hypersecretory conditions Hypersensitivity to it or other H2 antagonists Anaphylaxis, constipation, diarrhea, dizziness, headache, S-J syndrome, toxic epidermal necrolysis, necrotizing enterocolitis in fetus or newborn, angioedema, seizure, interstitial pneumonia, nosocomial pneumonia
Ranitidine Zantac 150mg SID-BID; 300mg SID hs; Pediatric (1 mo-16 yr): 2-10mg/kg/day divided BID po; IV: 2-4mg/kg q6-8 hrs; Prevention of heartburn, > 12 yrs and OTC: 75 mg before food/drink, max 150mg/day Histamine H2 antagonist Short term and maintenance treatment of duodenal ulcer, gastric ulcer, GERD, active benign ulcer, erosive esophagitis, pathological hypersecretory conditions; part of a multidrug regimen for eradication of H. pylori to reduce risk of duodenal ulcer Hypersensitivity to it Abdominal pain, constipation, diarrhea, headache, bradyarrhythmia, S-J syndrome, toxic epidermal necrolysis, necrotizing enterocolitis in fetus or newborn, pancreatitis, agranulocytosis, aplastic anemia, pancytopenia, thrombocytopenia, hepatitis
Lansoprazole Prevacid 15-60mg SID, up to 90mg BID x usually 4-12 weeks; Pediatric: 15-30mg SID x up to 12 weeks Proton pump inhibitor, Substituted benzimidazole Short term treatment of active duodenal ulcers, maintenance Tx of healed duodenal ulcers, part of multidrug regimen to eradicate H. pylori, Tx and reduce risk of NSAID-associated gastric ulcer, Tx of GERD, promote healing of esophagus Hypersensitivity to it N/D, anaphylaxis, abdominal pain, constipation, headache, pancreatitis, S-J syndrome, toxic epidermal necrolysis, erythema multiforme, bone fracture, rhabdomyolysis, acute interstitial nephritis
Esomeprazole Nexium 20-40mg SID, up to 240mg/day Proton pump inhibitor, Substituted benzimidazole Oral: short-term (4-8 wks) Tx of erosive esophagitis; maintaining healing of erosive esophagitis; Tx of symptomatic GERD; as part of multidrug regimen to eradicate H. pylori; reduce risk of gastric ulcer from NSAID therapy Hypersensitivity to it, substituted benzimidazoles (omeprazole, lansoprazole) D/N, anaphylaxis, abdominal pain, constipation, flatulence, xerostomia, headache, somnolence, S-J syndrome, toxic epidermal necrolysis, erythema multiforme, angioedema, bone fracture, rhabdomyolysis, acute interstitial nephritis
Metoclopramide Metozolv, Reglan 10-15mg up to QID, Tx > 12 weeks not recommended; Pediatric: 0.1-0.2mg/kg/dose QID, max 5 doses/day po; IV: 1-2mg/kg before chemo & q2-4 hrs Antiemetic, Gastrointestinal agent, Prokinetic Oral: symptomatic Tx of diabetic gastroparesis, gastroesophageal reflux; IV/IM: prevention and/or Tx of N/V associated with chemo/post-Sx to stimulate gastric emptying and intestinal transit of Ba during radiological examination of stomach/small intestine Hypersensitivity to it, GI obstruction/perforation/hemorrhage, pheochromocytoma, Hx of seizures, concomitant use of agents likely to increase extrapyramidal rxns N/V, edema, asthenia, headache, somnolence, fatigue, neuroleptic malignant syndrome
Prochlorperazine Compro 5-10mg TID-QID, up to 150mg/day (antipsychotic); Pediatric > 10 yrs: 0.4mg/kg/day divided TID-QID, or 2.5mg q8-24 hrs Antiemetic, Antipsychotic, Tyipcal, Phenothiazine Management of N/V, psychotic disorders including schizophrenia and anxiety Hypersensitivity to it, severe CNS depression, coma, pediatric Sx, Reye's syndrome, use in children < 2 yrs or < 9kg Hypotension, constipation, xerostomia, akathisia, dizziness, phoyosensitivity, dystonia, blurred vision, prolonged QT interval, torsades de pointes, ineffective thermoregulation, diminished sweating, seizure, priapism
Fexofenadine Allegra 60mg BID or 180mg SID Histamine H1 antagonist, Second generation, Piperidine derivative Relief of symptoms associated with seasonal allergic rhinitis, treatment of chronic idiopathic urticaria, OTC labeling, relief of symptoms associated with allergic rhinitis Hypersensitivity to it Indigestion, dizziness, headache, somnolence, otitis media, dysmenorrhea, upper respiratory infection, fatigue, viral disease, cold, influenza
Doxazosin Cardura Titration up to 16mg/day (8mg for BPH, 16mg for hypertension) Alpha-1 blocker Treatment ofhyertension as monotherapy or in conjunction with diuretics, ACE inhibitors, beta-blockers, or calcium antagonists; Tx of urinary outflow obstruction and/or obstructive and irritative symptoms associated with BPH Hypersensitivity to it, quinazolines (prazosin, terazosin), Beers Criteria Edema, hypotension, nausea, dizziness, headache, somnolence, vertigo, fatigue, hepatitis, intraoperative flopy iris syndrome, priapism
Tamsulosin Flomax 0.4-0.8mg SID, 30 minutes after meal Alpha-1 blocker Treatment of signs and symptoms of BPH Hypersensitivity to it Infectious disease, backache, asthenia, dizziness, headache, insomnia, somnolence, abnormal ejaculation, rhinitis, retinal detachment, priapism
Oxybutynin Ditropan, Gelnique, Oxytrol 5mg BIG-TID, max QID; ER: 5-10mg initial, up to 30mg/day; Topical: 1 sachet SID; Transdermal: 3.9mg patch BIW Antispasmodic agent, Urinary Antispasmodic for neurogenic bladder (urgency, frequency, leakage, urge incontinence, dysuria); ER formulation also indicated for Tx of detrusor overactivity due to a neurological condition (e.g., sina bifida) Hypersensitivity to it, risk or diagnosis of narrow-angle glaucoma, urinary retention, gastric retention or conditions with severely decreased GI motility Application site erythema/rash, pruritus, constipation, diarrhea, xerostomia, angioedema, gastroenteritis, dizziness, somnolence, headache, confusion, seizure, psychotic disorder, mycosis
Tolterodine Detrol 1-2mg BID; ER: 2-4mg SID Anticholinergic agent Treatment of patients with overactive bladder with symptoms of urinary frequency, urgency, or urge incontinence Hypersensitivity to it, urinary retention, gastric retention, uncontrolled narrow-angle glaucoma Anaphylaxis, constipation, xerostomia, headache, angioedema, dementia, memory impairment
Sildenafil Revatio, Viagra ED: 50mg (25-100) SID 1 hr prior to sexual activity; Hypertension: 20mg TID, 4-6 hrs apart Phosphodiesterase-5 enzyme inhibitor Vigra: treatment of erectile dysfunction; Revatio: treatment of pulmonary arterial hypertension to improve exercise ability and delay clinical worsening Hypersensitivity to it, concurrent use of organic nitrates in any form, concurrent use with protease inhibitor regimen when sildenafil is used for pulmonary artery hypertension Erythema, flushing, indigestion, headache, insomnia, visual disturbance, epistaxis, rhinitis, myocardial infarction, priapism, decreased hearing, hemoglobin sickle cell disease with vaso-occlusive crisis
Epoetin Alfa Epogen, Procrit 50-150 units/kg TIW, 10,000 units TIW to 40-60,000 units SIW Colony stimulating factor Treatment of anemia associated with HIV therapy, chronic renal failure, reduction of allogeneic blood transfusion for elective, noncardiac, nonvascular surgery Hypersensitivity to human albumin or mammalian cell-derived products, uncontrolled hypertension, Hg > 12 N/V/D, edema, hypertension, pruritus, rash, constipation, indigestion, dizziness, headache, insomnia, paresthesia, cough, congestive heart failure, myocardial infarction, anemia, deep vein thrombosis, porphyria, cerebral ischemia, seizure, encephalopathy
Ferrous Sulfate (Oral) Feosol, Fer-In-Sol, Fer-iron, MyKidz Iron 10, Slow FE 300mg BID, up to 300mg QID; ER: 250mg SID-BID; Elemental: 8-27mg/day Iron salt Prevention and treatment of iron-deficiency anemias Hypersensitivity to it, iron salts, hemochromatosis, hemolytic anemia Constipation, dark stools, nausea, immune hypersensitivity reaction
Iron Sucrose (Injection) Venofer Elemental: max 1g over 14 days, 10 doses total, or 3 doses/week; 100-300mg/dose slow infusion Iron salt Treatment of iron-deficiency anemia in chronic renal failure, including nondialysis-dependent patients and dialysis-dependent patients receiving erythropoietin therapy Hypersensitivity to it, evidence of iron overload, anemia not caused by iron deficiency N/V/D, anaphylaxis, hypotension, leg cramping, headache, seizure, loss of consciousness, collapse, dyspnea
Amoxicillin Amoxil, Moxatag 250-500mg q8 hrs, 500-875mg BID, XR: 775mg SID Antibiotic, Penicillin Treat bacterial infections Hypersensitivity to it, other penicillins, other beta lactams N/V/D, rash, anaphylaxis, fungal infection
Amoxicillin & Clavulanate Potassium Amoclan, Augmentin Based on amoxicillin component: 250-500mg q8 hrs, 875mg BID Antibiotic, Penicillin Treat bacterial infections Hypersensitivity to it, other penicillins, other beta lactams, Hx of cholestatic jaundice or hepatic dysfunction; XR: severe renal impairment/hemodialysis N/V/D, rash, anaphylaxis, fungal infection, S-J syndrome, cholestasis, hepatotoxicity, mycosis
Created by: cstclair4