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Neoplasm Objectives
Neoplasm for Pathophysiology
| Question | Answer |
|---|---|
| Benign tumor | Not cancer |
| Malignant | cancer |
| Benign tumor | normal cells/similar |
| Benign tumor | differentiated |
| benign tumor | mitosis normal |
| benign tumor | growth slow |
| benign tumor | expanding mass |
| benign tumor | remains localized |
| benign tumor | rare systemic effects |
| benign tumor | not life threatening unless in brain |
| Malignant | varied in size & shape w/large nuclei |
| malignant | many undifferentiated |
| malignant | mitosis increased & atypical |
| malignant | rapid growth |
| malignant | cells not adhesive |
| malignant | invades nearby tissues |
| malignant | metastasizes to distant sites via blood & lymph vessels |
| malignant | systemic effects often present |
| malignant | life threatening by tissue |
| malignant | destruction & spread of tumors |
| local effects of malignant | pain, obstruction, tissue necrosis |
| systemic effects | weight loss, anemia, severe fatigue, infections bleeding, paraneoplastic syndromes |
| Warning signs of cancer | unusual bleeding or discharge anywhere in the body |
| Warning signs of cancer | change in bowel or bladder habit (prolong diarrhea) |
| Warning signs of cancer | sore that does not heal |
| Warning signs of cancer | change in wart or mole (size, shape, color) |
| Warning signs of cancer | unexplained weight loss |
| Warning signs of cancer | anemia, low hemoglobin, persistent fatigue |
| Warning signs of cancer | persistent cough or hoarseness w/o reason |
| Warning signs of cancer | solid lump, painless, in breast, testes or anywhere |
| common diagnostic test for cancer | blood test |
| common diagnostic test for cancer | tumor markers |
| common diagnostic test for cancer | x-ray, ultrasound, MRI, CT |
| common diagnostic test for cancer | cytoliogic (biopsies) |
| spread of malignant tumors | invasion/stage 1 |
| spread of malignant tumors | metastasis/stage 4 |
| spread of malignant tumors | seeding/stage 2, 3 |
| staging cancer | primary tumor size (t) |
| staging cancer | node involvement (n) |
| staging cancer | metastasis (m) |
| cachexia | weight loss (severe muscle wasting) |
| initiating | cause 1st change to cell |
| promoters | hormones & environmental chemicals |
| exposure | continued |
| metastasis | spreading |
| risks | genetic, viruses, radiation, chemicals, biologic, age, diet, hormones |
| prevention | limit sun exposure, regular medical & dental exams, alter diet |
| host defenses against cancer | cancer suppressors/Tcells |
| tumor nomenclature | tumors named according to a system |
| carcinogenesis | process which normal cells transformed into cancer cells |
| treatment measures | curative, palliative |
| adverse effects of chemotherapy/radiation | nausea, hair loss, loss of appetite |
| implication for physical therapy | active, want to eat |
| treatment measures | surgery, radiation, chemotherapy, immunotherapy |
| dose limiting | low cell count |
| anaplasia | lack of differentiation |
| transformation | conversion of normal cells to cancerous |
| general treatment side effects | #1 fatigue |
| palliative | alleviating symptoms |