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Cytokines (IL)

Cytokines - immuno

IL 1 TH1 --> Fever
IL 2 recruits everyone, T cell proliferation
IL 3 B cell proliferation
IL 4 B cell proliferation, IgE and all class switching
IL 5 ONLY IgA class switching
IL 6 acute phase reactants
IL 8 Neutrophil recruiters
IL 10 SUPRESSES cell mediated immunity (T/MP)
IL 12 ENHANCES cell mediated immunity
IFN alpha inhibits viral replication
IFN beta inhibits viral replication (used to treat MS)
IFN gamma activates MP & NK cells, suppresses humoral immunity
TNF alpha weight loss, inc. BMR, secreted by MP ---> cell death
TNF beta weight loss, inc. BRM secreted by T cells ---> cell death
Created by: 757820961