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Insulin exam

Insulin info

QuestionAnswer
Insulin are classified as Antidiabetic agents.
Whats the function of insulin insulin functions to transport glucose into the cell and in the liver releases glucose into the blood.
List the prototypes of insulin injectable and oral
Beta cells secrete hypoglycemia hormone in cells.
Delta cells release somatostatin-a hormone that inhibits both glucagon and insulin.
F cells synthesize and secrete pancreatic polypetides used in digestion.
Describe the functions of insulin Regulates carbohydrte metabolism. Helps regulate fat and protein metabolism. Results in lower blood glucose.
Describe the function of liver inregards to insulin uptake and storage of glucose as glycogen, excess glucose is stored as fat, suppresses the liver producing glucose.
Active insulin must bind to cell receptor sites.
Type 1 diabetics insulin replaces hormone insulin normally produced in pancreas.
Type 2 diabetics when diet/wt control have failed to maintain blood glucose levels.
Insulin may also be used by altered heath states like pregnancy, surgery, trauma, infection, renal, liver, endocrine dysfunction.
Insulin is necessary for normal carbohydrate, protein, and fat metabolism.
Sources of insulin commercially available. Sometimes indivdually formulated for use in infants with diluents.
Injectable insulin is used with Type I, occassionally type II, and some gestational diabetes.
Different types and species of insulin have different pharmacological properties.
Human insulin now is preferred for pregnant women or individuals expected to use insulin only intermittently, diabetic women considering pregnancy, individuals with allergies or immue resistance to animal-derived insulins or intialating insulin therapy.
pharmacodynamics insulin is required to provide
Insulin controls storage and metabolism of carbo, proteins, and fat.
Insuln converts glucose to glycogen in the liver.
insulin's absorption varies by type and route of medication.
How must insulin be injected (where) when GI enzymes destroy insulin oral.
When using SC or needles for insulin pump, make sure to rotate sites.
Insulin contraindications hypersensitivity or insulin resistance (requiring change in insulin type).
Insulin is cautioned with children, elderly, and pregnant.
Insulin interacts with glucocorticoids and thiazide diuretics (incl. glood glucose). Alcohol increases insulin effect; betablocerks mask hypoglycemia.
Patients response to insulin changes how pt responds to other drugs, can produce side effects.
Variables to consider with insulin insulin type, injection technique and site, insulin antibodies, somogyl effect and dawn phenomenon. Illness or high stress, hypo and hyperglycemic states.
Humalog onset 10-15 min.
Humalog Peak .5 - 1.5 hrs.
Huamlog duration 3-5 hrs.
Regular insulin onset .5-1 hr.
Regular insulin peak 2-3 hrs.
Regular insulin duration 6-8 hrs.
Patient education for hypoglycemia tachycardia, irritability, restlessness, excessive hunger, diaphoresis, depression, blood sugar less than 60mg/dl
Patient education for hyperglycemia polyuria, polydipsia, polyphagia, wt loss, fatigue, frequent infections, blood sugr above 99 mm/dl when fasting.
Lente Humulin L onset 1-3 hours
Lente Humulin L peak 6-12 hrs.
Lente Humulin L duration 16-24 hrs.
Ultra Lente glargine onset 4-8 hrs.
Ultra Lente glargine peak 12-18 hrs.
Ultra Lente glargine duration 2-48 hrs.
Created by: starz_1_girl