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Daniel's random 7
| Question | Answer |
|---|---|
| Leishmainia | hepatosplenomegaly, pancytopenia, spiking fevers |
| leishmeinia dx | macrophaegs containing amastigotes, peripheral blood smear |
| leishmeinia tx | sodium stibogluconate |
| which drug metabolizer into phenobital and phenylethylmalonamide? | primidone used for anticonvulsant |
| pneumo causes 40-65 | Strep pneumo, H. influenzae, anaerobes, viruses, mycoplasma |
| S. pneumo >65 | strep pneumo, influenza virus, anaerobes, H. influ,, gram negative rods |
| what do ATP ? | ATP - tRNA activation (charging) by aminoacyl tRNA synthetase |
| and GTP do in protein translation | |
| I hyperchylomicronemia | chylomicrons, TG cholesterol increase, LPL deficiency or altered C2, presents with pancreatitis, HSM, eruptive/pruiritic anthomas; no increased risk for atherosclerosis |
| II familial hyperholesterolemia | LDL, cholesterol, AD, absent or decreased LDL receptor; accelerated atherosclerosis, tendon (achilles) xanthoma; corneal arcus |
| hypertriglyceridemia | VLDL, TG, hepatic VLDL overproduction; pancreatitis |
| abetalipoproteinemia | deficiency in B100 and B48 |
| babesia and lyme's disease | ixodes tick |
| urease positive | proteus, ureaplasma, nocardia, cryptococcus, h. pylori, klebsiella |
| non linear DNA viruses | papilloma and polyoma (circular, supercoiled); hepadnaviruses - circular, incomplete |
| clonorchis sinensis | undercooked fish; inflammation of biliary tract -> pigment gallstones -> associates w/ cholangiocarcinoma; praziquentel |
| taenia solium (cestode, tapeworm) tx | praziquantel -> use bendazole for neurocysticercosis |
| leptospira interrogans | weil's dz -> severe jaundice and azotemia from liver and kidney dysfunction |
| M protein | group A strep; prevents phagocytosis |
| carcinoid tumor | sheets of uniform cells; minimal to no variation in shape and size of tumor cells; from enterochromaffin cells of intestinal mucosa |
| btonchioalveolar carcinoma | columnar cells that line the alveolar septa w/o vascular or stromal invasion; pneumonia like symptoms |
| B6 def | convulsions, hyperirritability, peripheral neuropathy (INH and OCP), sideroblastic anemia (decreased Hb, increased Fe) |
| B6 needed for synthesis of? | cystatione, heme, niacin, GABA |
| B6 function | transamination, decarboxylation, glycogen phosphorylase |
| hunter's | aggressive behavior; no corneal clouding |
| enzyme deficient in Hunter's | iduronate sulfatase |
| roseola HHV6 | high fevers for several days -> may cause seizures; followed by diffuse macular rash |
| obligate anaerobe features | foul smell (short chain fatty acids), hard to culture, produce CO2 and H2 in tissue |
| giemsa | borellia, plasmodium, trypanosomes, chamydia |
| segmented viruses | BOAR bunyavirus (12), orthomyxovirus (8), arenavirus (2), reovirus (10-12) |
| yellow fever | monkey or human |
| yellow fever | black vomitis, jaundice |
| F fusion protein | paramyxovirus |
| silver stain | fungi, i.e. pneumocystis, legionella |
| onchocerca volvulus | ivermectin, river blindness, blackflies, black skin nodules, black sight |
| blood supply to proximal 1/3 ureter | renal artery |