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Biology II Final 2

Lectures 31-44

QuestionAnswer
Environment limits survival and reproduction through... competition due to overpopulation, predation, and physical environment
Genetic effects phenotypic differences are often heritable because differences in individuals are in part due to differences in their alleles
Uniformitarian Principle major forces of change have been the same throughout Earth's history
Uniformitarian Principle implies gradualism that change is slow and at a constant rate such as erosiion, sedimentation, tectonic movement
Homologous phenotypes share a common ancestor, but the homologous structures do not have to have the same function
Criteria for homologous phenotypes extensive phenotypic similarity, common developmental sources, seriation (fossil species and developmental sequences between related living species)
Analogous phenotypes share common functions in common environments, but do not share common ancestor-common functions does not imply common
Convergent phenotypes evolve independently in unrelated taxa, which provides evidence for natural selection
Rules for calculating relative frequencies: -Frequency(Ai)=#Ai/(#A1...n) for n alleles -Sum of all allelic frequencies must equal 1.00
Hardy Weinberg Equilibrium the genotype frequencies and gene frequencies of a large, randomly mating population remain constant provided immigration, mutation, and selection do not take place
Gene pool metaphor random mating of individuals (genotypes) is equivalent to random fusion of gametes
Intersection Rule Prob(A AND B)=P(A) x P(B)
Union Rule Prob(A OR B)=P(A) + P(B)
Example: Freq(A1)=p, Freq(A2)=q -Freq(A1A1)= p x p = p^2 (homozygous) -Freq(A2A2)= q x q = q^2 (homozygous) -Freq(A1A2)=(p x q)+(q x p)= 2pq (hetero)
Genotypic frequencies vs. allele frequencies -allele frequencies=p,q,r,... -genotypic frequencies=A1, A2, A3...
Forces change allele frequencies (4) 1) selection 2)random genetic drift 3)migration between unlike populations 4)mutation
Assortative mating (nonrandom) changes genotypic frequencies but not allele frequencies
Absolute fitness in the general selection model number of survivors/total
Relative fitness in the general selection model absolute fitness/best of absolute fitness (ratio closest to 1)
Measured rate of change of allele frequencies delta(p or q)= p or q(after selection)- p or q(before selection)--->delta p is opposite of delta q
Mean population Fitness (W-bar) expected genotypic frequencies x genetic fitnesses
Mean allelic fitnesses W(A1)- W(A2)= rate, direction
Reverse heterosis heterozygote less fit than homozygotes
Therapeutic use of antibiotics least likely to cause evolution of ABR-->high dosages, 2 or more antibiotics, brief use but finish the course treatment
Prophylactic use of antibiotics continual selection for ABR-->low dosages, 1 antibiotic, continuous use
Erratic use of antibiotics most effective at generating ABR-->use of many antiobiotics (one at a time though), rapid switches between all antibiotics, variable or inadequate dosages
Mechanisms of antibiotic resistance 1) fortress=reduced inflow of antibiotic to keep out antibiotics 2) flush toliet=increased excretion of antibiotic so what comes in gets pumped back out 3) muffler=inactivation of antibiotic 4) armor=alteration of target molecule (ex. reverse RNA)
Genetic variation mutation is the ultimate source to genetic variation, because genetic variation is reduced in the random genetic drift and directional selection processes
Inbreeding Depression (ID) genetic basis of ID is increased expression of rare recessive alleles in homozygous form--->rare recessives are often harmful though causing sterility, high juvenile death rates, low resistance to diseases, etc.
Inbreeding Depression can be fixed by migration-introducing new alleles to the population
Intrinsic barriers biological barriers that prevent mating between two sympatric yet divergent populations
Prezygotic barriers (intrinsic barrier) prevent gamete fusion through habitat differences, timing differences, mating behaviors, and gamete incompatibility
Postzygotic barriers (intrinsic barrier) involve genetic mismatches between parent gametes that result in progeny including inviability and infertility
Nesting hierarchy Kingdom, Phylum, Class, Order, Family, Group, Species
Clock formula -t=time from the common ancestor to either descendent species -R=rate of evolution in # of changes/# positions/year -D(a,d)=divergence between the common ancestor and either descendent species -D=divergence between the two descendent species
Peripatric model of speciation new species form by long-range dispersal of "colonists" that may establish small daughter populations
Vicariance model of speciation geographic barriers arise to split populations or populations move around them, which then evolve so differently from one another to result in an intrinsic barrier between them
RNA World Hypothesis RNA contains introns that self-splice them out, RNA is self replicating, proteinless ribosomes can elongate polypeptide chains, introns in RNA can add amino acids to tRNA and remove them
RNA is inferior to DNA and proteins DNA is more stable than RNA, 20 amino acids allow more informational combinations than four RNA bases do, so DNA and proteins eventually replaced RNA in major roles
RNA roles in present day ribosome skeleton, tRNA, RNA primer for DNA chain replication, and some coenzymes
Enantiomers within living systems are more bias towards the levo enantiomers and has been maintained through enzymatic specificity
5-Kingdom System between plants+fungi and animals -Plants=stationary; photoautotrophic -animals=mobile; chemoheterotrophic -fungi=stationary; chemoheterotrophic -protista=unicellular eukaryote; chemoheterotrophic and/or photoautotrophic -monera=unicellular prokaryote; include all trophic forms
3 Major Domains of Life Archaebacteria-evolved when free energy was rare on earth (old), diverged into eubacteria and eucaryota
Prokaryotic cells usually small, anaerobic+aerobic metabolism, no nucleus, reproduce asexually through fission, has mesosomes but no other membrane-bound organelles, ingestion through absorptive (soak up dissolved compounds from medium), and no mobile cell cytoskeleton
Eukaryotic cells large, mostly aerobic, has a nucleus, reproduces through mitosis and meiosis, has membrane-bound organelles, ingests through cytotic/absorptive (pick up large particles and digest them), and has mobile cell cytoskeleton
Oxygen is essential for present-day eukaryotes catabolism (respiration), and anabolism (adding oxygen to anaerobically synthesized carbohydrate)
Production of molecular O2 depends on aerobic photosynthesis and nitrogen fixation
Biological evidence of eukaryotes achritarchs (fossil spore cases formed by eukaryotes) and stearanes (molecular fossils of eukaryote metabolism)
Membrane organelles increase internal surface/volume ratios of cells by increasing rates of internal traffic flow through lysosomes, compartmentalize cells into little spaces with each doing a specialized function, and organize assembly lines for the orderly synthesis of movement of materials in a linear array
Endogenous Origin Hypothesis two-membrane organelles evolved (mitochondria and platids) from pre-existing structures of an ancestral eukaryotic cell
Endosymbiont Hypothesis mitochondria and plastids evolved as bacterial symbionts that got taken up by phagocytosis and enclosed in lysosome but no digested so now lives inside eukaryotic cells
Evidence supporting Endosymbiont Hypothesis mitochondria and plastids resemble prokaryotes in size, chromosomal structure, sensitivity to antibiotics, and synthesize own rRNA and tRNA, and self-replicate population inside cells
Sexual reproduction produces genetic variation by fusion of gametes from different parents, independent assortment of chromosomes, and crossing-over between chromosomes
Crossing over products heritable because they are linked DNA sequences, while other genotypic combinations are broken up in meiosis and not transmitted through generations
Terrestrial stresses related to absence of water through support, transport, and dehydration
Protosomes larval characteristics (coelomate animal) 8-cell stage of cleavage that is spiral and determinate, mouth develops from blastopore, and solid mass of mesoderm splits to form coelom
Deuterostomes larval characteristics (coelomate animal) 8-cell stage of cleavage that is radial and indeterminate, anus develops from blastopore, and folds of archenteron forms coelom
Earliest vertebrates agnathid (jawless) fish
Jaws first seen in Placoderm (skin plate) fish
Williston's Law of evolution of segmented phenotypes unused segments tend to become lost, and used segments tend to be kept, but some of remaining segments evolve new functions because other maintain ancestral function
Amphibians evolved and became dominant due to locomotion provided by the lobe fin with was modified to support limbs, and resistance to dehydration provided by leathery skin and lungs
First wholly terrestrial vertebrates amniotes who were adapted to reproduce internally and egg contained amnion, chorion, allantois, and yolk sac
Amphibians tied to aquatic habitats for food (fish) and reproduction for external fertilization and larval development
Amnion in amniote egg anti-dehydration device that provides hydraulic support
Chorion in amniote egg formed from ectoderm and mesoderm, expands and contacts air space to aid in uptake of gas
Allantois in amniote egg formed from mesoderm and endoderm, its the dump site where all waste goes, but also evolved to aid in gas exchange
Yolk sac in amniote egg used to build cell membrance, and food supply for embryo
Eukaryotic genome consists of unique single copy DNA, and repeat DNA (multiple copies of DNA section)-more DNA in a cell, more of it is repeat DNA
Beta-family beta, epsilon, gamma, delta, pseudo-beta 1&2
Alpha-family alpha 1&2, pseudo-alpha1, fetal 1&2
Kinds of Homology Orthology between species, and paralogy between phenotypes within species
Gene duplication events chances of unequal cross-over increase as number of adjacent gene repeats increase
Retro-transposition can be transcribed into DNA and reverse transcribed into rRNA
Polyploidization similar gene clusters are shared between chromosomes
Functional significance of multigenes in evolution transcript amplification (higher transcript production rates), protected function through redundancy (loss of one gene does not cause loss of function), heterogenous function (different copies can evolve different functions)
Oxygen uptake curves oxygen binding at one monomer in a tetramer increases the probability of oxygen binding at adjacent monomers, which increases as oxygen is added, and increases efficiency of oxygen transport between lungs and cells
Angiosperm advances in phenotype due to pollinators being attracted to their flowers or odors, animals attracted to their fruits, and discouraging herbivores through poisonous berries, seeds, etc.
Selective coevolution evolution by each species in association is affected by its interactions with other species
Pollinators can promote speciation by restricting gene flow between sympatric plant populations. Ex)2 parent species and the hybrid daughter species all have different pollinators causing the hybrid daughter species to stabilize as separate species
Congruent phylogenies expected if hosts restrict opportunities for gene flow between populations of their symbionts
Kin Selection central concept is inclusive fitness (WI) where alleles are heritable units of evolution and relatives share copies of alleles inherited from common ancestors
Individual's inclusive fitness based off reproduction by self and reproduction through aided relatives
Relatedness measures the degree to which two individuals share copies of the same alleles due to descent from common (shared) ancestors
Hamilton's Rule states that an individual (Ego) should donate aid if: benefit>cost (b*r > c*1--->b/c > 1/r)
Two elements of Hamilton's Rule b/c measures ecological effects and 1/r measures genetic effects -b=reproductive benefit to a relative of aid -c=reproductive cost to ego of giving aid -r-relatedness of aided relative to ego -1=relatedness of ego to ego
Reciprocal altruism to have a friend, be one. Ex)vampire bat
Characteristics of mammals and bats lifestyle philopatric matrilineal societies (stay within family group), food donation to young, mutual grooming (test who is reliable partner), and operant conditioning (ability to learn identity marks)
Calculating relatedness r(ab)=sum of p(1/2)^n r(ab)=relatedness of a to b p=all possible paths of allelic descent from shared ancestors n=# of meiotic steps in each path of descent
Created by: ajohannes
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