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last minute MSK
| Question | Answer |
|---|---|
| fibrinoid necrosis surrounded by palisading histiocytes | subcutaneous rheumatoid nodules |
| baker's cyst behind the knee | rheumatoid arthritis |
| MCP and PIP invovlement | rheumatoid arthritis |
| type 3 hypersensitivity | RA |
| anti-IgG antibody | positive rheumatoid factor |
| anti CCP antibody | less sensitive but more specific for RA |
| strong association with HLA DR4 | RA |
| symmetric joint involvement, systemic symptoms (fever, pleuritis, pericarditis, fatigue) | rheumatoid arthritis |
| tx is NSAIDS, COX2 inhibitors glucocorticoids, DMD (methotrexate, sulfasalazine) | RA |
| increased risk of B cell lymphoma | sjogren's syndrome |
| increased CK, increased aldolas, positive ANA, anti JO1 | polymyositis and dermatomyositis |
| Gottron's papules, heliotrope rash, shawl and face rash, mechanics hands, increased risk of malignancy | dermatomyositis |
| increased breast and lung cancer | dermatomyositis |
| caused by CD8+ T cell induced injhury to muofibers | polymyositis |
| most often involves shoulders | polymyositis |
| progressive symmetric proximal muscle weakness caused by CD8+ t cell | polymyositis |
| >11 of 18 tender points | fibromyalgia |
| exotoxin attacks stratum granulosum | SSSS |
| white, painless plauqes on tongue that cannot be scraped off | hairy leukoplakia =- EBV |
| anaerobic bacteria and S. pyogeness -> creptius from methane and CO2 | necrotizing fasciitis |
| infection of dermis and subq tissues from S. pyogens or s. aureus | cellulitis |
| honey colored crusting | impetigo s. aureus or s. pyogenes |
| monoarticular, migratory arthritis with an asymmetrical pattern | gonococcal arthritis |
| synovitis (i.e. knee), tenosynovitis (hand), dermatitis (pustules) | septic arthritis |
| chronic arthritis | TB, lyme |
| causes of osteonecrosis/avascular necrosis | trauma, high dose corticosteroids, alcoholism, sickle cell, prednisone |
| increased ESR, normal CK | polymyalgia rheumatica |
| no muscular weakness, pain and stifness in shoulders, hips, fever, malaise, weight loss | polymyalgia rheumatica a/w temporal arteritis |
| fibrinoid necrosis surrounded by palisading histiocytes | Rheumatoid nodules |
| OA or RA has joint ankylosis (fusion)? | RA |
| artery damaged in femoral neck fracture (common in osteoporosis)? | medial femoral circumflex artery |
| thoracic outlet syndrome- sign | radial pulse disappears when turn head to ipsilateral side of compression of brachial plexus and subclavian artery/vein by cervical rib |
| symptoms of GVHd | jaundice, hepatosplenomegaly, diarrhea, maculopapular rash |