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Bio 141
Bio 141 Final Review
| Question | Answer |
|---|---|
| Primary organ for drug metabolism? | liver |
| four major body compartments contains the smallest average volume in liters? | vascular space |
| the only once a day anticholinergic? | tiotropium bromide |
| correct dosage of theophylline is best monitored by? | serum drug levels |
| generic substitutes tend to be less expensive. T ot F | true |
| number of goblet cells per square millimeter of normal airways | 6000 |
| greatest limitation to effective patient use of a dry powder inhaler | patients ability to provide, flow rate of 30 to 90 l/min |
| failure of the patient to throughly shake and MDI device | reduction is the total dose or increase in total dose |
| some examples of disease states that could benefit from the use of adrenergic bronchodilators | asthma, bronchitis, emphysema and bronchiectasis |
| common side effects of theophylline therapy | headache, gastric upset, anxiety, nervousness and diuresis |
| xanthines typically have which physiological therapy | cardiac muscle stimulation, bronchial smooth muscle relaxation and CNS stimulation |
| direct acting cholinergic agent often used in bronchial challenge test | methacholine |
| increase mucociliary or cough efficency | mucokinetics |
| inhales areosols may have effects on the body | local and systemic |
| theophylline blood levels can be increased by | pneumonia, corticosteroids, beta blockers |
| using ipratropium aerosols should avoid contact with? | eyes |
| epinephrine stimulates ehich receptor sites | beta 2 |
| relaxation of smooth airway muscle when the patient has reversible airflow ostruction is a general indication for the use of? | adrenergic bronchodilators |
| quaterny ammonium compounds cause bronchodilation | blocking cholinergic sites |
| combivent is a combination drug including which agents? | albuterol and atrovent |
| study of drugs- orgin, properties and interactions with living organisms | pharmacology |
| patient is recieving gentamicin via small- volume nebulizer | set flow rate to 12 l/min instead of the typical 7-8 l/min |
| one millimeter (ml) is equal to how many drops (gtts) of liquid | 16 |
| how many cubic centimeters do you need for a 2.5 mg dose of terbutalone sulfate, using a 0.1% solution | 2.5 |
| airway anatomic structure is responsible for providing the majority of mucus secreations | submucosal glands |
| drugs can be legally designates as an orphan | true |
| what parts of the pharmacokinetic phse of a drug? | absorption, metabolism and elimination |
| how much medication actually reaches the childs lungs | 10-15% |
| one cubic centimeter is equivalent to how many millimeters? | 1 |
| administer atropine to a patient, effects you commonly see? | dry mouth, decreased mucus production, increased heart rate |
| one TSP is the equivalent of how many millimeters? | 5 |
| racemic epinephrine as we use to treat comes in what percentage of solution | 2.25% |
| theophylline can be used effectively in treating | asthma, apnea of prematurity, COPD |
| atrovent (ipatropium) is primarily used for what purpose in COPD | maintenance treatment of airflow obstruction in COPD |
| Ipatropium agents are indicated for which conditions | allergic phinitis, common cold, nonallergic phinitis |
| levabuterol chemically is? | the single R-isomer of albuterol |
| peripheral airways, the speed of mucocillary transport is approximately | 1.5mm/min |
| recommend a reservoir device to be used in conjuction with MDI | antistatic valves holding chamber is best |
| physicians are required by law to include their DEA registration number when perscibing medications | true |
| should albuterol MDI's routinely be refrigerated? | albuterol should be stored at room temp. |
| how long should you wait between the first and second dose of albulterol | pause 1-5 minutes |
| patient administer a drug with an MDI if no spacer is available or needed | hold MDI several cenitmeters in front of the open mouth |
| cholinergic stimulation will produce which effects | bronchoconstriction, increased mucus secretion, miosis, decreased heart rate, salivation |
| drug that stimulates skeletal muscle and the CNS strongly | caffine |
| disease with hypersecretion or poor clearance of secretions include? | cystic fibrosis, Pneumonia, primary ciliary dyskensia |
| how does acetycysteine (mucomyst) work? | substitues sulfhydryl radicals for disulfide bonds in mucus |
| adrenergic bronchiodilators work by mimiking actions of? | epinephrine |
| patients report that the common side effect of anticholinergic bronchodilators is | dry mouth |
| recommend ehich areosol medications to help provide relief from subglotic swelling | racemic epinephrine |
Created by:
jseyfried
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