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Paramedic_K

Drugs

QuestionAnswer
Epinephrine_Class Sympathomimetic
Epinephrine_Mechanism of Action Direct acting alpha and beta agonist. Alpha: vasoconstriction. Beta 1: positive inotropic, chronotropic and dromotropic effects. Beta 2: bronchial smoothe muscle relaxation and dilation of skeletal vasculature.
Epinephrine_Indications Cardiac arrest (V-fib/pulseless V tach, asystole, PEA) symptomatic bradycardia as an alternative infusion to dopamine, sever hypotension secondary to bradycardia when atropine and transcutaneous pacing are unsuccessful
Epinephrine_Indications Pt 2 symptomatic bradycardia as an alternative infusion to dopamine, sever hypotension secondary to bradycardia when atropine and transcutaneous pacing are unsuccessful, allergic reactions, anaphylaxis, asthma.
Epiniphrine_Contraindications Hypertension, hypothermia, pulmonary edema, myocardial ischemia, hypovolemic shock
Epinephrine_Adverse Reactions Hypertension, tachycardia, arrhythmias, pulmonary edema, anxiety restlessness, psychomotor agitation, nausea, headache, angina
Epinephrine_Drug Interactions Potentiates other sympathomimetics, deactivated by alkaline solutions (ie. sodium bicarbonate), monamine oxidase inhibitors (MAOIs) may potentiate effects, beta blockers may blunt effects.
Epinephrine_How Supplied 1:1,000 solution: ampules and vials containing 1mg/mL. 1:10,000 solution: prefilled syringes containing 1 mg in 10 mL (0.1 mg/mL). Auto-injector (EpiPen): 0.5 mg/mL (1:2,000)
Epinephrine_Dosage and Administration ADULT ADULT: Mild allergic reactions and asthma: 0.3-0.5 mg (0.3-0.5 mL of 1:1,000)SC. Anaphylaxis: 0.1 mg (1 mL of 1:10,000) IV/IO over five minutes.
Epinephrine_Dosage and Admin: CARDIAC ARREST ADULT Cardiac Arrest: IV/IO dose: 1 mg (10 mL of 1:10,000 solution} every 3-5 minutes during rescitation. Follow each dose with 20mL flush, elevate arm for 10 to 20 seconds after dose. Higher dose: Higher doses up to .2 mg/kg may be used for specific conditions
Created by: Kirstine