Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove ads
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards




share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

NURS 572 Ch 75 asthm

Pharm Ch 75 asthma

QuestionAnswer
What 2 classes of drugs are used to tx asthma anti-inflammatory-----bronchodilators
What drugs in the anti-inflamm class are used glucocorticoids---NSAIDs
what drugs are in the bronchodilator class Beta-2 agonists---anticholinergics---leukotriene modifiers---methylxanthines
what is the advantage to inhalation tx delivers drug where it's needed ---especially with spacer---21% to lung vs. 9% without spacer
3 types of inhalation tx MDIs = metered dose inhalers-----DPI = dry powder inhaler -----nebulizer
what are the MOST EFFECTIVE anti-asthma drugs inhaled glucocorticosteroids most effective
local ADRs of inhaled steroids oropharyngeal candidiasis----dysphonia (voice impairment)----prevent by gargline after admin, using a spacer
systemic ADRs of long-term use of inhaled steroids osteoporosis-----retarded growth rate, may catch up----cataracts/glaucoma------rare HPA axis suppression
name 3 inhaled steroids ending in -ide budesonide-----ciclesonide-----flunisolide
name 4 inhaled steroids ending in -one beclomethasone-----fluticasone-----mometasone----triamcinolone
name 2 oral/systemic steroids generally used for asthma prednisolone----predenisone
name 2 oral/systemic steroids if don't need mineralcorticoid activity (prolong action preferred) methylprednisolone-----dexamethasone
Action of Beta-2 adrenergic agonists most effect for ACUTE bronchospasm------prevention of exercise induced bronchospasm-----often included in routine tx----also prophylactic
how can Beta-2 agonists be admin inhaled or oral
ADRs of oral Beta-2 agonists tremor common, tol developse----systemic Beta-1 SEs possible (tachy, angina)-----HYPOKALEMIA
ADRs of inhaled Beta-2 agonists much lower incidence of tremor, systemic Beta-1, hypokalemia
name 4 quick/short acting inhaled Beta-2 agonists albuterol----levabuterol----bitolterol----pirbuterol
albuterol quick/short inhaled B-2 agonist
levalbuterol quick/short inhaled B-2 agonist
bitolterol quick/short inhaled B-2 agonist
pirbuterol quick/short inhaled B-2 agonist
name 2 long acting inhaled Beta-2 agonists salmeterol---formoterol (and alfrometerol)
what are 2 oral beta-2 agonists albuterol, terbutaline
what is are 2 non-steroidal anti-inflammatory inhaled drugs cromolyn-----nedocromil
what drug is SAFEST of all anti-asthma meds that would be cromolyn
what is MOA of cromolyn, nedocromil NOT A BRONCHODILATOR-----phrophylaxis---suppresses inflammation
ADRs of cromolyn, nedocromil virtually no systemic bwo 8% absorption---cough---bronchospasm
name 2 anti-cholinergics that can be inhaled with or without addition of albuterol ipratropium----tiotropium
cromolyn class nonsteroidal anti-inflamm
nedocromil class nonsteroidal anti-inflamm
MOA anti-cholinergics blocks the muscarinic receptors that would cause bronchocon--> bronchoDIL
are anticholinergics more/less effective than Beta-2 agonists less effective, but additive for pts who are difficult to control
ADRs of anicholinergics dry mouth, throat irritation---system effects rare
ipratropium class anticholinergic
tiotropium - longer acting - its class anticholinergic
methylxanthines MOA this class not established
name 1 drug in methylxanthine class theophylline - rarely used
why is theophylline rarely used has a very narrow therapeutic window. ADRs a,n,v,d----CNS nerv/insom,conv-----CV tachy,dys,angina
theophylline class methylxanthine
leukotriene modifier MOA suppress leukotrienes so they can't bronchocon--> net effect bronchDIL
name 1 leukotriene modifiers montelukast-qd
which leukotriene has no liver toxicity SE montelukast
Created by: lorrelaws