Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

NURS 572 Ch 73 gout

pharm - ch 73 - gout

gout is usually, but not always characterized by hyperuricemia
acute episodes are ALWAYS characterized by urate crystals in joint fluid
what causes hyperuricemia/urate crystals excessive production of uric acid-----impaired renal excretion of uric acid
Acute tx of gout includes tx for pain, inflammation using these 3 classes of drugs anti-inflam/cholchicine----NSAIDs---corticosteroids
PREVENTION of gout bwo 2 mechanisms decrease prodcution of uric acid---increase excretion (uricosuric)
anti-inflamm agent to treat ACUTE gouty attack while offering some bridging to prevent subsequent attack colchicine - oral
We only give colchicine for 2 doses - why wicked GI SEs n/v/DIARRHEA----rare nephrotoxicity
name 2 drugs that are for chronic use/preventative ---lower uric acid levels allopurinol---febuxostat
MOA of drugs to lower uric acid = allopurinol, febuxostat inhibit xanthine oxidase so it can't convert purines to uric acid
are drugs to lower uric acid preventative? yes, if there's less uric acid, then we are preventing goit
why don't we use febuxostat as often $$$ but it works same as allopurinol
ADRs allopurinol gen well tolerated-----Rare----hypersensitivity syndrome = rash/fever/eosinophilia/liver/kidney dysfunciton----cataracts-----GI,HA
ADRs febuxostat same as allopurinol except no dermatological hypersensitivity
name 2 uricosurics that increase urinary excretion of uric acid probenecid-----sulfinpyrazone
why use uricosurics only for PREVENTION of attacks----NO BENEFIT for acute gouty attack
ADRs/class of probenecid and sulfinpyrazone uricosurics with these ADRs---risk of nephrolithiasis---PT MUST DRINK 2-3 LITERS OF WATER PER DAY ---GI---hypersensitivity reactions
Created by: lorrelaws