Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Endocrine drugs

QuestionAnswer
Propylthiouracil tox skin rash,agranulocytosis, aplastic anemia, hepatotoxicity
methimazole tox teratogen, skin rash, agranulocytosis, aplastic anemia
levothyroxine, triidothyronine tachycardia, heat intolerance, tremors, arryhthmias
GH use Turner's syndrome, gh deficiency
octreotide use acromegaly, carcinoid syndrome, gastrinoma,gucagonoma
oxytocin use stimulates labor, uterine contractions, milk let-down, controls uterine hemorrhage
ADH (desmopressin) use CENtrAL pituitary DI
demeclocycline use SIADH
rapid acting insulin lispro aspart
intermediate acting insulin NPH
long acting insulin glargine, detemir
MOA of insulin binds insulin receptor (Tyrosine kinase activity) liver: increases glucose stored as glycogen muscle: increases glycogen and protein synthesis, K+ uptake fat: aids TG storage
insulin tox hypoglycemia, hypersensitivity reaction
insulin use life threatening hyperkalemia, stress induced hyperglycemia, Type 1 and 2 DM, gestational diabetes
sulfonylureas tox disulfiram like effects (first generation) hypoglycemia (second generation)
first generation sulfonyureas tolbutamide chlorpropramide
second generation sulfonylureas glyburide glimepiride glipizide
MOA of sulfonylureas close K+ channel in beta cell membrane -> cell depolarizes -> triggering of insulin release via increased Ca influx
biguanide (metformin) decreased glucoconeogenesis, increased glycolysis, increased peripheral glucose uptake (insulin sensitivity)
can be used in patietns without islet function metformin
contraindicated in renal failure metformin
weight gain, edema, hepatotoxicity, heart failrue pioglitazone, rosiglitazone
glitazones/thiazolidinediones MOA increases insulin sensitivity in peripehral tissue binds to PPAR gamma nuclear transcription regulator
alpha glucosidase inhibitors acarbose, miglitol
inhibits intestinal brush border alpha glucosidases. Delayed sugar hydrolysis and glucose absorption -> decreased postprandial hyperglycemia acarbose, miglitol
pramlintide hypoglycemia, nausea, diarrhea
pramlintide MOA decreases glucagon
exenatide increases insulin, decreases glucagon release
pancreatitis exenatide
Created by: ilovemusic007
Popular USMLE sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards