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sepsis
| Question | Answer |
|---|---|
| when you have an infection that has created a systemic inflammatory response | Sepsis |
| systemic inflamatoory response syndrome | have two of the following: >90bpm, >20 breaths per min, >38degrees C or 100.4F, temp <36C or 96.8F, WBC>12000or <4000 |
| you have at least one end organ dysfunction, hypoperfusion or hypotension | severe sepsis |
| you have sepsis induced hypotension that is persisting despite adequate fluid resuscitation | septic shock |
| with this you need to measure lactate within 6 hours, blood cultures before antibiotics, broad spec. antibiotics with in 3 hours of ER, fluid bolus for hypotension or lactate >4, CVP >8 within 6 hours for septic shock, | Resucitation Bundle |
| you need low dose steroids withing 24hours of dx of sepsis, drotecogin slfa (antiinflammatory) w/in 24hours, Glucose control 70-150, if on vent median inspiratory plateau pressure < 30 over 1st 24hrs to prevent further lung damage | Management bundle |
| Every time a blood culture is ordered what else should be ordered | lactate levels |
| targets microvasuclar dysfunction, reduce microvascular thrombosis | Drotrecogin Alfa |
| do not give Drotrecogin Alfa if the patient has | active internal bleeding, or epidual catheter |
Created by:
dnoyes
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