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Pharm toxicities res


pseudophredrine, phenylephrine hypertension, CNS stimulation/anxiety (pseudophed)
dextromethorphan mild opioid effect when used in excess, mild abuse potential
cromolyn toxicity is rare
beta 2 agonist - salmeterol tremor, arryhtmia
H1 blocker - diphenhydramine, dimenhydrinate, chlorpheniramine sedation, antimuscarinic, anti-alpha adrenergic - dry effects, urinary retention
loratadine, fexofenadine, desloratadine, cetirizine decreased entrance into CNS
danazol weight gain, edema, acne, hirsutism, masculinization, decreased HDL, benign hepatic adenomas, menstrual irregularities, pseudotumor cerebri
sildenafil, vardenafil headache, flushing, dyspepsia, impaired blue green color vision, life threatening hypotension if taken with nitrates
ritodrine, terbutaline
mifepristone heavy bleeding, GI n/v, anorexia, abdominal pain
HRT increased risk of endometrial cancer, increased CV risk
clomiphene hot flashes, ovarian enlargement, multiple simultaneous pregnancies, visual disturbances
leuprolide antiandrogen, n.v
testosterone (methyltestosterone) masculinization in female, reduces intratesticular testosterone -> gonadal atrophy, premature closure of epiphyseal plates, increased LDL, decreased HDL
estrogen increased risk of endometrial cancer, bleeding in postmenopausal women, clear cell vagina in females exposed to DES in utero, increased risk of thrombi
C/I of estrogen ER positive breast cancer history of Dvts
Created by: ilovemusic007