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14 & 15
Question | Answer |
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Capabilities of a pathogen | maintain reservoir, leave its reservoir & enter a host, adhere to the surface of the host, invade the body of the host, evade the body's defenses, multiply within the body, leave the body & return to its reservoir or enter a new host |
symbiosis | relationship between normal microbiota & host |
commensalism | one organism benefits, other is unaffected |
mutualism | both organisms benefit |
parasitism | one organism benefits at the expense of the other |
probiotics | live microbes applied to or injested into the body, intended to exert a beneficial effect |
Koch's postulates | used to prove the cause of an infectious disease |
Normal microbiota colonize host | opportunist pathogens, survive in spite of body's defenses, protect host |
protection of host | occupying niches that pathogens might occupy, producing acids, producing bacteriocins |
Human reservoirs | incubatory carriers, chronic carriers |
incubatory carriers | infected, have not developed symptoms yet |
chronic carriers | harbor pathogen, never become sick ie Salmonella typhi, streptococcus pyogenes |
animal reservoirs | both domestic & wild, new forms of disease develop; zoonosis |
zoonosis | human disease caused by a pathogen with an animal reservoir, ie Rabies, lyme disease, influenza |
environmental factors | soil: Colstridium tetani water: Vibrio cholera & Salmonella typhi |
Portals of entry | mucous membranes, skin, parental route |
mucous membranes | respiratory, gastrointestinal, genitourinary tract, conjunctiva |
parental route | direct deposit beneath the skin |
ID50 | infections dose for 50% of test pop. Bacillus anthracis: 10-50 endospores on skin |
LD50 | lethal dose for 50% of test pop. Botulinum: 0.03 ng/kg |