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14 & 15
| Question | Answer |
|---|---|
| Capabilities of a pathogen | maintain reservoir, leave its reservoir & enter a host, adhere to the surface of the host, invade the body of the host, evade the body's defenses, multiply within the body, leave the body & return to its reservoir or enter a new host |
| symbiosis | relationship between normal microbiota & host |
| commensalism | one organism benefits, other is unaffected |
| mutualism | both organisms benefit |
| parasitism | one organism benefits at the expense of the other |
| probiotics | live microbes applied to or injested into the body, intended to exert a beneficial effect |
| Koch's postulates | used to prove the cause of an infectious disease |
| Normal microbiota colonize host | opportunist pathogens, survive in spite of body's defenses, protect host |
| protection of host | occupying niches that pathogens might occupy, producing acids, producing bacteriocins |
| Human reservoirs | incubatory carriers, chronic carriers |
| incubatory carriers | infected, have not developed symptoms yet |
| chronic carriers | harbor pathogen, never become sick ie Salmonella typhi, streptococcus pyogenes |
| animal reservoirs | both domestic & wild, new forms of disease develop; zoonosis |
| zoonosis | human disease caused by a pathogen with an animal reservoir, ie Rabies, lyme disease, influenza |
| environmental factors | soil: Colstridium tetani water: Vibrio cholera & Salmonella typhi |
| Portals of entry | mucous membranes, skin, parental route |
| mucous membranes | respiratory, gastrointestinal, genitourinary tract, conjunctiva |
| parental route | direct deposit beneath the skin |
| ID50 | infections dose for 50% of test pop. Bacillus anthracis: 10-50 endospores on skin |
| LD50 | lethal dose for 50% of test pop. Botulinum: 0.03 ng/kg |