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Chp. 21 bio

genomes, proteomes, and Bioinformatics

QuestionAnswer
Genome refers to the entire complement of Dna an organism has
Genomics the study of genomes
Human has 2.91 billion base pairs
why study genomes? -to find all the genes and learn functions -to learn how mutations cause various diseases -to develop therapies for diseases -to examine evolution
Human Genome Project name given to a joint effort to completely sequence the entire DNA sequence of 22 human autosomes and 2 sex chromosomes
Junk dna consists of repetitive dna. raw dna sequence (at least 90%)
Centromeres and telomeres are mostly repetitive DNA.
some regions of repetitive dna are transposons
Transposons are unique DNA sequences that can relocate from one part of genome to another. causing rearrangements.
Only 2% of our genomes codes for proteins.
98% of genome is regulatory, repetitive and unkown.
Proteome is a set of all the proteins made by a cell.
Alternative Splicing is why the proteome is larger than genome.
Bioinformatics is a field that uses computers, math, and stats to record store and analyze large sequences of data.
why is Bionformatics used? used to find genes, regulatory regions, evolutionary relationships.
gene annotation analyzing genes in DNA sequence.
Homologues sequences two sequences are related. had a common ancestor.
Bionformatics programs Blast database.
Created by: 1574238891
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