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Chp. 21 bio
genomes, proteomes, and Bioinformatics
| Question | Answer |
|---|---|
| Genome | refers to the entire complement of Dna an organism has |
| Genomics | the study of genomes |
| Human has | 2.91 billion base pairs |
| why study genomes? | -to find all the genes and learn functions -to learn how mutations cause various diseases -to develop therapies for diseases -to examine evolution |
| Human Genome Project | name given to a joint effort to completely sequence the entire DNA sequence of 22 human autosomes and 2 sex chromosomes |
| Junk dna | consists of repetitive dna. raw dna sequence (at least 90%) |
| Centromeres and telomeres | are mostly repetitive DNA. |
| some regions of repetitive dna are | transposons |
| Transposons are | unique DNA sequences that can relocate from one part of genome to another. causing rearrangements. |
| Only 2% of our genomes | codes for proteins. |
| 98% of genome is | regulatory, repetitive and unkown. |
| Proteome | is a set of all the proteins made by a cell. |
| Alternative Splicing is | why the proteome is larger than genome. |
| Bioinformatics | is a field that uses computers, math, and stats to record store and analyze large sequences of data. |
| why is Bionformatics used? | used to find genes, regulatory regions, evolutionary relationships. |
| gene annotation | analyzing genes in DNA sequence. |
| Homologues sequences | two sequences are related. had a common ancestor. |
| Bionformatics programs | Blast database. |