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General Anesthetics


MOA of general anesthetics Most are thought to act at GABA-A receptor - chloride channel
Inhaled anesthetic with a low blood/gas partition coefficient Nitrous oxide
Inversely related to potency of anesthetics Minimum alveolar anesthetic concentration (MAC)
Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents Halothane and methoxyflurane
Most inhaled anesthetics SE Decrease arterial blood pressure
Inhaled anesthetics are myocardial depressants Enflurane and halothane
Inhaled anesthetic causes peripheral vasodilation Isoflurane
nhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis Halothane
Inhaled anesthetic, less likely to lower blood pressure than other agents, and has the smallest effect on respiration Nitrous oxide
Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency Methoxyflurane
Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia Nitrous oxide
Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm Desflurane
DOC for malignant hyperthermia that may be causedby use of halogenated anesthetics Dantrolene
IV barbiturate used as a pre-op anesthetic Thiopental
Benzodiazepine used adjunctively in anesthesia Midazolam
Benzodiazepine receptor antagonist, it accelerates recovery from benzodiazepine overdose Flumazenil
This produces "dissociative anesthesia ", is a cardiovascular stimulant which may increases intracranial pressure, and hallucinations occur during recovery Ketamine
Opioid associated with respiratory depression, but is used in high risk patients who may not survive full general anesthetia Fentanyl
State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide Neuroleptanesthesia
Produces both rapid anesthesia and recovery, has antiemetic activity and commonly used for outpatient surgery, may cause marked hypotension Propofol
Created by: tessah10