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DIT neuro path
| Question | Answer |
|---|---|
| dementia workup | STDs, copper and b12, TSH, brain MRI to r/o infarct, stroke, nL P hydroceph, mini mental staus exam. |
| lou gherigs | ALS |
| senile plaques, neurofibrillary tangles | alzheimres |
| presents at birth as floppy baby | Wernig hoffman |
| lewy bodies | parkinson's, lewy body disease |
| atrophy of caudate nucleus causing chorea | huntingtons |
| depigmentation of substantia nigra | parkinsons |
| both UMN and LMN signs (spasticity and weakness) | ALS |
| dementia and visual hallucinations | lewy body |
| dementia and personality changes or aphasia | picks |
| intranuclear inclusions seen in HSV encephalitis | cowdry type A |
| cytoplasmic inclusions pathognomonic of rabies | Negri bodies |
| neuronal inclusions characteristic of parkinson's disease | lewy bodies |
| cytoplasmic inclusion bodies a/w aging | lipofuscin granules |
| dark cytoplasmic pigment in neurons of the substantia nigra and locus coeruleus, not seen in pts with parkinson's | melanin |
| eosinophilic, rodlike inclusions in hippocampus of alzheimer's pts | hirano bodies |
| diagnostic of alzheimer's disease | plaques, NF tangles |
| filamentous inclusions that stain with silver, do not survive neuronal death | pick bodes |
| filamentous inclusions that stain with PAS and ubiquitin | lewy bodies |
| disease a/w lew bodies | parkinsons, lewy body disease |