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DIT fuel usage

in feeding vs. fasting states

What fuels are produced in the post absorptive period? glucose from liver, FA from adipose tissue
What fuels are used in post absorptive period mm, brain, and tissues use GLUCOSE
when does gluconeogenesis begin? 4 - 6 hrs after the last meal
when does gluconeogenesis become fully active? when gllycogen stores are depleted - 10 to 18 hours after the last meal.
What fuels are produced in early starvation (24 hours after last meal) glucose from gluconeogenesis, with some glycogen from glycogenolysis; FA from adipose
What fuels are used in early starvation (24 hrs post) brain uses glucose, mm + use some glucose but mostly FA
48 hrs post meal what fuels are produced? Glucose from gluconeogenesis, FA from adipose, KB from liver
48 hrs post meal what fuel is used? Brain uses glucose and some KBs; mm + use mostly FA and some KBs
what metabolic scenario favors the synthesis of KBs excess acetyl CoA from FA metabolism
What can't use KBs? RBCs
in prolonged starvation, what fuel is produced? glucose, FA, KBs
in prolonged starvation what fuel is used brain uses KBs, mm + use FA and some KBs
95% of energy from glucose (2/3 glycogen, 1/3 gluconeogenesis); 5% of energy from ketone bodies overnight fast
60% of energy from ketone bodes, 40% from glucosee (gluconeogenesis) 3 day fast
Created by: kayjames



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