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DIT neuro pharm quiz
| Question | Answer |
|---|---|
| endogenous agonist to mu receptor | morphine |
| endogenous agonist to delta receptor | enkephalin |
| endogenous agonist to kappa receptor | dymorphin |
| opiod cough suppressant commony used with the expectorant guaifenesin | dextromethorphan |
| opioid commonly used in the tx of diarrhea | loperamide and diphenoxylate |
| opioid commonly used in the tx of acute heart failure | morphine |
| opioid receptor antagonist | naloxone/naltrexone |
| non-additive weak opioid agonist | tramadol |
| partial opioid agonist that causes less respiratory depression | butorphanol |
| how is barbiturate overdose managed | symptomatically |
| how is benzo overdose managed | flumazenol |
| IV, a/w hallucinations and bad dreams | ketamine |
| inhaled, SE: neprhotoxic | methoxyflurane |
| IV, most common drug used for endoscopy | midazolam and fentanyl |
| inhaled, SE: convulsions/seizures | enflurane |
| inhaled, SE: hepatotoxic | halothane |
| IV, used for rapid anesthesia induction and short procedures | propofol |
| inhaled, used for rapid anesthesia | NO |
| IV, decreases cerebral blood flow (important in brain surgery) | thiopental |
| IV, does not induce histamine release like morphine | fentanyl |
| High triglyceride content increases risk of pancreatitis with long-term use | propofol |
| agesnts used in the Tx of Parkinson's disease | (BALSA) bromocriptine, amantadine, levodopa/carbidopa, selegiline, antimuscarinics |
| side effects common to most antiepileptics? | diplopia, ataxia, sedation, nystagmus, dizziness |
| toxic SE of phenytoin | lupus-like, induced p450, gingival hyperplasia, hirsutism, baby issues, steven-johnson |
| mechanism of dantrolene | prevents release of Ca fro SR of Sk m. |
| mechanism of local anesthetics? | block Na+ channels (preferentially activated ones) |
| Which nerve fibers are blocked first with local anesthesia? | myelinated and small |
| which drugs can be used to reverse NM blockade? | neostigmine (cholinesterase inhibitors) |
| mechanism of drugs used to treat alzheimers? | NMDA receptor antagonists and ACh inhibitors |
| mechanism of sumatriptan | serotonin agonist. |
| Sumatriptan is contraindicated in which populations? | CAD, printzmetal's angina, pregnancy. |