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DIT RBC path

basophilic stippling lead poisoning
heinz and bite cells G6PD deficiency
schistocytes DIC
acanthocytes (spur cells) abetalipoproteinemia
howell-jolly bodies asplenia
microcytic anemia + swallowing difficulty + glossitis iron deficiency (plummer vinson)
microcytic anemia + >3.5% HbA2 beta thal minor
megaloblastic anemia not correctable by B12 or folate orotic aciduria
megaloblastic anemia along with peripheral neuropathyy B12 deficiency
microcytic anemia + basophilic stippling lead poisoning
microcytic anemia reversible with B6 sideroblastic anemia
HIV positive pt with macrocytic anemia AZT
Normocytic anemia + red urine in the morning PNH
normocytic anemia and elevated creatinine CKD --> decreased EPo
nearly always IgM cold agglutinins
occur regularly in infx with M.pn, EBV, some malignancies cold agglutinins
disease occurs when there is circulation to a cold extremity. IgM binds RBC antigen --> complement cascade cold agglutinins
Nearly always IgG warm agglutinins
seen in viruses (EBV, HIV), SLE, malignancies, congenital immune abn warm agglutinins
rate limiting step of heme synthesis alpha aminolevulinic acid synthase
cause of ITP decreased platelet survival d2 Gp IIb/IIIa abs
what is the defect in bernard-soulier disease GpIb (platelet to collagen adhesion)
what is the most common inherited bleeding disorder? VWD
whate are some of the hereditary syndromes of thrombosis? Factor V Leiden, Prothrombin gene mutation, ATIII def, protein C/S def
Hams test PNH
DEB test Fanconi's anemia
Heinz bodies G6PD def
D dimers DIC
basophilic stippling lead poisoning, thalassemia, iron def, ACD
osmotic fragility test hereditary spherocytosis
+ ristocetin test VWD
Created by: kayjames