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DIT Calcium quiz

QuestionAnswer
functions of vitamin D increased intestinal absorption of calcium and phosphate, increased bone resorption of calcium and phosphate
How does PTH affect calcium increases it
How does PTH affect phosphate decreases it
what cells secrete calcitonin C cells of the thyroid (parafollicular)
2 signs of hypocalcemia Chovsteks, Trousseaus
What are the 2 most common causes of primary hyperparathyroidism? adenoma, parathyroid hyperplasia
Underlying cause of renal osteodystrophy nephron loss causes decreased vitamin D which leads to phosphate retention, increased PTH, decreased Ca (and bone lesions), incerased Alk Phos
What agents can be used to treat osteoporosis? Ca, Vit D, bisphosphanates, pulsatile PTH, Calcitonin, Tamoxifen/roloxifene, testosterone
What hormones work via tyrosine kinase second messengers? GH, prolactin
What cancers are a/w hypercalcemia? squamous cell cancers, RCC, breast cancer, MM
young woman with short stature and shortened 4th and 5th metacarpals. Endocrine disorder? pseudohypoparathyroidism (albright's hereditary osteodystrophy
mechanism of bisphosphonates? inhibits osteoclasts (=less breakdown)
possible causes of hypocalcemia? thyroid surgery, a/i destruction, Digeorge (causing hypoPTH), pseudohypoPTH
Created by: kayjames
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