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DIT female repro
female reproduction quiz
| Question | Answer |
|---|---|
| What do theca cells make that granulosa cells don't? | ANDROSTENEDIONE because they have 17 hydroxylase |
| What do granulosa cells do? | they steal androstenedione from theca cell and use aromatase to convert it to ESTRADIOL |
| What are the target cells of LH | Theca cells |
| What are the target cells of FSH | Granulosa cells |
| production of thick mucus that inhibits entry of sperm into the uterus | progesterone |
| induces LH surge | estrogen |
| uterine smooth muscle relaxation | progesterone |
| follicle growth | estrogen |
| maintenance of pregnancy | progesterone |
| hepatic synthesis of transport proteins | estrogen |
| withdrawal leads to menstruation | progesterone |
| what drug would you give to inhibit prolactic secretion? | dopamine |
| when does beta hCG appear in the urine during pregnancy? | 2 weeks after conception (4 weeks after LMP) |
| what hormonal changes are seen during menopause? | decreased estrogen d2 increased FSH, LH and GNRH |
| What is the underlying cause of PCOS? | increased LH leads to increased androgens leads to increased estrogens |
| Clinical manifestations of PCOS | acne, hirsutism, amenorrhea, infertility, Obesity, Insulin resistance |
| Treatment of PCOS | Gonadotropin analogs, OCPs, clomiphene, spironolactone, metformin |
| produces AFP | yolk sac tumor |
| estrogen secreting, causes precocious puberty | follicular cyst |
| intraperitoneal accumulation of mucinous material | mucinous cystadenoma |
| testosterone secreting, causes virilization | sertoli-leydig |
| psammoma bodies | serous cystadenocarcinoma |
| multiple different tissue types | teratoma |
| lined with fallopian tube-like epithelium | serous cystadenoma |
| ovarian tumor + ascites + hydrothorax | (meigs) fibromas |
| call-exner bodies | granulosa cell tumor |
| resembles bladder epithelium | brenner tumor |
| elevated beta-hCG | choriocarcinoma, dysgerminoma |
| risk factors for endometrial carcinoma | hypoplasia, increased estrogen, PCOS, obesity, unopposed HRT, age, tumor |
| risk factors for ovarian cancer | family history, ovulation |
| risk factors for cervical cancer | exposure to HPV |