Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

DIT antifungals

QuestionAnswer
interferes with microtubule function Griseofulvin
swish and swallow for oral candidiasis (thrush) Nystatin
cell wall synthesis inhibiter used in invasive aspergillosis caspofungin
binds ergosterol -> membrane pores amp B
inhibits ergosterol synthesis Azoles, terbinafin
most common Tx for onychomycosis terbinafin, griseofulvin
SE: arrhythmias and nephrotoxicity Amp B
Deposits in keratin containing tissues griseofulvin
inhibits hormone synthesis and cytochrome P450 azoles
SE: liver dysfunction azoles
SE: teratogenic, carcinogenic Griseofulvin
Used for cryptococcal meningitis in AIDS fluconazole or intrathecal Amp B
converted to fluorouracil, inhibits DNA synthesis Flucytosine
Drug of choice for sporotrichosis Itraconazole
What antifungal can be used intrathecally for fungal meningitis Amp B
what is the clinical use of griseofulvin oral tx of superficial infections, inhibits dermatophytes
Teratogenic, Carcinogenic, confusion, HA, P450 inducer griseofulvin
squalene ---> lanosterol blocked by... Terbinafin
Lanosterol --->ergosterol blocked by... -azoles
pyrimidine synthesis blocked by... flucytosine
microtubules disrupted by... griseofulvin
membrane disrupted by.. Amp B and Nystatin
Created by: kayjames