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NRS 572 29, 70

Drug Drill pain, cox inhib, NSAID, acetaminophen

QuestionAnswer
analgesic, antipyretic, hepatotoxic, no COX-1 SEs acetaminophen
COX-1, 2 inhib, cardioprotective, stroke prevention, Reyes, hypersensitivity must avoid all NSAIDs acetylsalycilic acid (ASA)
less COX-1,2 SEs with less cardioprotection bwo of reversible platelet effect non-acetyl salicylates
name 5 non-acetyl salicylates (sodium, choline, magnesium, choline/magnesium)salicylate and salicylate
short acting, IV available, non-selective NSAIDs ibuprofen, ketorolac
long acting non-selective NSAIDs naproxen, piroxicam, oxaprozin
naproxen long acting non-sel NSAID
piroxicam long-acting non-sel NSAID
oxaprozin long-acting non-sel NSAID
Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed meloxicam, nabumetone
meloxicam Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed
nabumetone Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed
non-selective NSAID, less GI ulceration etoldolac
Misc nonselective NSAID meclofenemate
Misc - topical patch/gel/hepatotoxic diclofenac
misc-salicylate deriv that metabolizes into this class diflunisal
COX-2 inhibitor celecoxib
celecoxib SEs predisposed to platelet mediated clotting thrombus (non-cox-1 mech). same renal SE. lessened GI, Cox-1 platelet mech)
does celecoxib offer cardioprotection nope
Created by: lorrelaws
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