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NRS 572 29, 70
Drug Drill pain, cox inhib, NSAID, acetaminophen
Question | Answer |
---|---|
analgesic, antipyretic, hepatotoxic, no COX-1 SEs | acetaminophen |
COX-1, 2 inhib, cardioprotective, stroke prevention, Reyes, hypersensitivity must avoid all NSAIDs | acetylsalycilic acid (ASA) |
less COX-1,2 SEs with less cardioprotection bwo of reversible platelet effect | non-acetyl salicylates |
name 5 non-acetyl salicylates | (sodium, choline, magnesium, choline/magnesium)salicylate and salicylate |
short acting, IV available, non-selective NSAIDs | ibuprofen, ketorolac |
long acting non-selective NSAIDs | naproxen, piroxicam, oxaprozin |
naproxen | long acting non-sel NSAID |
piroxicam | long-acting non-sel NSAID |
oxaprozin | long-acting non-sel NSAID |
Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed | meloxicam, nabumetone |
meloxicam | Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed |
nabumetone | Non-selective NSAID (more Cox-2 action), metabolites, still GI bleed |
non-selective NSAID, less GI ulceration | etoldolac |
Misc nonselective NSAID | meclofenemate |
Misc - topical patch/gel/hepatotoxic | diclofenac |
misc-salicylate deriv that metabolizes into this class | diflunisal |
COX-2 inhibitor | celecoxib |
celecoxib SEs | predisposed to platelet mediated clotting thrombus (non-cox-1 mech). same renal SE. lessened GI, Cox-1 platelet mech) |
does celecoxib offer cardioprotection | nope |