Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove ads
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards




share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

NURS 572 Pharm 28

Opioids, nonopioid centrally acting analgesics

QuestionAnswer
MOA opioid agonists activate Mu (--> resp dep) and Kappa (--> psychotomimetic, diuretic)
strong opioids given oral, IM, rectal (3) morphine, hydromorphone, oxymorphone
very short acting opioids (2) meperidine, remifentanyl
meperidine uses/ADRs labor/delivery, neurotoxic metabolite (avoid drug), anticholinergic (watch tachy)
remifentanyl break through pain, short acting, metab by plasma esterases
long-acting opioids (2) methadone, levorphanol
methadone uses pain, maintenance, detox
levorphanol class long acting opiate agonist
chronic pain opioids (3) fentanyl, alfentanil, sufentanyl
routes of admin fentanyls inj, ITS, transdermal, lozenge, lollipop, buccal, nasal spray
moderate efficacy opioids (3) codeline, oxycodone, hydrocodone
codeine combo, very limiting SEs n/v
oxycodone alone or combo
hydrocodone combo only
MOA mixed agonist/antagonist opioids activate either mu/kappa, antagonize the other
benefit/limitation mixed opioids raises resp depr ceiling(+), but pyschotomimetic reactions
name 4 mixed opioids pentazocaine, nalbuphine, butorphanol, buprenorphine
which 2 mixed opioids contraindicated cardiac pts due to increased cardiac load pentazocaine (contains naloxone too), butorphanol
class of nalbuphine mixed opioid
class of buprenorphine mixed opioid with diff actions at mu/kappa
class of penazocaine mixed opioid, oral combo with naloxone, or injection
name 4 opiate antagonists that can lead to withdrawal if pt is opioid tolerant naloxone, naltrexone, methyl-naltrexone, alvimopan
class, use naloxone opioid antagonist. rapid, short acting block mu/kappa. detox/cravings
class, use of naltrexone opioid antagonist. maintenance post detox. doesn't prevent cravings
class, use of alvimpoan only post-op ileus (antagonizes SE of urinary retention). strict controls, in pt only
opioid ADRs that do NOT develop tolerance miosis, consitpation
opioid ADRS where tolerance develops urinary retention, biliary colic, ICP increases, orthostatic hypoTN, emesis, sedation, decreased respirations, cough suppression
MOA non-opioid central acting analgesics weak mu agonist, but either blocks reuptake Ser, Nor or both
class, moa tramadol non opioid centrally acting analgesic blocks reuptake of nor, ser
class, moa tapentadol non opioid centrally acting analgesic blocks reuptake of ser only
Created by: lorrelaws