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FA important CKs
important cytokines
| Question | Answer |
|---|---|
| secreted nby macrophages | IL-1, IL-6, IL-8, IL-12, TNFalpha |
| secreted by all T cells | IL-3 |
| secreted from Th1 cells | IL-2, IFN-gamma |
| secreted from Th2 cells | Il-4, IL-5, Il-10 |
| endogenous pyrogens | IL-1, IL-6 |
| chemotactic factor for neutrophils | IL-8 |
| Tells T cells to become Th cells. Activates NK cells | Il-12 |
| mediates septic shock | TNF-alpha |
| causes leukocyte recruitment, vascular leak | TNF-alpha |
| like GM-CSF = bone marrow stem cell growth and differentiation | IL-3 |
| stimulates T cells | IL-2 |
| activates macrophages and Th1 cells. supresses Th2 cells. Antiviral and Antitumor properties | IFN-gamma |
| tells T cells to be Th2 cells | IL-4 |
| stimulates IgE and IgG | IL-4 |
| Promotes growth of B cells | IL-4 |
| Promotes differentiation of B cells | IL-5 |
| IgA and eosinophils | IL-5 |
| modulates inflammatory response | IL-10 |
| inhibits actions of Th1; activates TH2 | IL-10 |