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FA important CKs

important cytokines

secreted nby macrophages IL-1, IL-6, IL-8, IL-12, TNFalpha
secreted by all T cells IL-3
secreted from Th1 cells IL-2, IFN-gamma
secreted from Th2 cells Il-4, IL-5, Il-10
endogenous pyrogens IL-1, IL-6
chemotactic factor for neutrophils IL-8
Tells T cells to become Th cells. Activates NK cells Il-12
mediates septic shock TNF-alpha
causes leukocyte recruitment, vascular leak TNF-alpha
like GM-CSF = bone marrow stem cell growth and differentiation IL-3
stimulates T cells IL-2
activates macrophages and Th1 cells. supresses Th2 cells. Antiviral and Antitumor properties IFN-gamma
tells T cells to be Th2 cells IL-4
stimulates IgE and IgG IL-4
Promotes growth of B cells IL-4
Promotes differentiation of B cells IL-5
IgA and eosinophils IL-5
modulates inflammatory response IL-10
inhibits actions of Th1; activates TH2 IL-10
Created by: kayjames