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DIT Gram positive
| Question | Answer |
|---|---|
| What skin infections can be caused by both Strep pyogenes and Staph aureus? | Folliculitis, Cellulitis, Impetigo |
| What types of infections does GBS (agalactiae) cause in neonates? | Pneumonitis, Meningitis, Sepsis |
| What organisms are most commonly implicated in subacute endocarditis? | Staph Epidermidis, Viridans Strep, Enterococci |
| What organism is most implicated in ACUTE endocarditis? | Staph Aureus |
| What is the most common aerobic skin flora? | Staph Epidermidis |
| Causes scalded skin syndrome | staph aureus |
| white membrane on pharynx | corynebacterium diptheriae |
| pharyngitis -> glomerulonephritis | Group A Strep |
| Most common cause of meningitis | S. pneumoniae |
| Most common cause of osteomyelitis | Staph Aureus |
| serious newborn infections | Listeria, Group B strep, (E. Coli) |
| Infant with poor muscle tone | C. Botulinum |
| Diarrhea after using antibiotics | C. Diff |
| Respiratory distress in a postal worker | B. Anthrax |
| Otitis media in children | S. pneumoniae |
| Cellulitis | Staph aureus or strep pyogenes |
| What is the mechanism of action of botulinum toxin? | Heat Labile toxin inhibits ACh release at the NMJ |
| Potato salad leads to vomiting that is better after 10 hours. What's the organism? | Staph Aureus |
| What infections are caused by strep pyogenes (GAS)? | pyogenic = pharyngitis, cellulits, impetigo. toxigenic = scarlet fever, TSS immunologic = rheumatic fever, acute glomerulonephritis |
| Novobiocin sensitive | Staph epidermidis |
| novobiocin resistant | Staph saphrophyticus |
| optochin sensitive, bile soluble | strep pneumoniae |
| optochin resistant, bile insoluble | viridans strep |
| bacitracin sensitive | GAS (s. pyogenes) |
| bacitracin resistant | GBS (agalactiae) |
| grows in bile and 6.5% NaCL | Enterococcus |
| Protein A binds Fc-IgG, inhibiting complement fixation and phagocytosis | Staph aureus |
| a superantigen that binds to MHC II and T cell receptor causing polyclonal T cell activation | TSST |
| biofilms | Staph epidermidis |
| Lancet shaped. encapsulated. IgA protease | Strep Pneumo |
| consequence of abs to M protein | enchance host defenses against GAS but can give rise to rheumatic fever |
| detects recent GAS infection | ASO titer |
| screen pregos at 35-37 weeks and give intrapartum penicillin if positive | GBS |
| exotoxin inhibits protein synthesis via ADP ribosylation of EF-2 | diptheria toxin |
| spore forming, obligate anaerobe bacilli | Clostridia |
| blocks glycine and GABA release from renshaw cells in spinal cord | C. Tetani |
| alpha toxin (lecithinase = PL) cause myonecrosis and hemolysis | C. Perfringens |
| Toxin A (enterotoxin) binds to the brush border of the gut | C. Diff |
| Toxin B (cytotoxin) destroys the cytoskeletal structure of enterocytes | C. Diff |
| C. Diff treatment | Metronidazole |
| Black eschar surrounded by edematous ring. Caused by lethal factor and edema factor | B. anthracis (cutaneous) |
| facultative intracellular microbe acquire by ingestion of unpasteurized milk/cheese/deli meets or by vaginal transmission during birth | Listeria monocytogenes |
| tumbling motility and actin rockets | Listeria |
| SNAP | Sulfa for nocardia, actinomyces use penicillin |
| 2 forms of hansen's disease | Lepromatous (weak T cell immunity, communicable) Tuberculoid (intact T celll response) |