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bio test 3 chapter 13
| Question | Answer |
|---|---|
| What are linked genes? | Genes located on the same chromosome |
| According to Mendel’s principle of independent assortment, the results of the testcross should be in a ratio of | 1:1:1:1 |
| Morgan ended up observing a ? of parental phenotypes and a ? of recombinant phenotypes | high percentage, Low percentage |
| What are parental phenotypes? | Offspring are identical to the original P generation |
| What are recombinant phenotypes? | Offspring have different combinations of traits from those of the P generation |
| Morgan hypothesized that the genes were linked and a genetic recombination occurred. What is genetic recombination? | A process in which crossing-over occurred during meiosis |
| Genes located on the sex chromosomes are called | sex-linked genes |
| The recombination frequency between any two linked genes reflect the | distance between them on their chromosome |
| Recombination frequencies can be used to make a | map of a chromosome showing relative locations of genes |
| Genes located on the chromosomes other than sex chromosomes are called | autosomes |
| In humans, the autosomes are chromosomes # | 1 to 22 |
| Different set of alleles on sex chromosomes in the males and females are inherited in a pattern called | sex linkage |
| Morgan proved there are genes on the X chromosome that determine | non-sexual traits |
| The genes for non-sexual traits on the X chromosome are called ? They are always ? | x-linked genes, recessive |
| In an X-linked pattern of inheritance, which sex is more likely to inherit the disorder? Why? | male, Males need to receive only one copy of the allele on the X chromosome to develop the trait Females must receive two copies of the recessive allele |
| What is X inactivation? | Early during embryonic development, one of the two X chromosomes in each cell is randomly inactivated |
| What are chromosomal mutations? | Changes in chromosome structure or chromosome number |
| How are chromosomal structure changed? | 1. Deletion: a segment is lost from a chromosome 2. Duplication: a segment of the chromosome is repeated 3. Translocation: a segment is switched b/w two nonhomologous chromosome 4. Inversion: a segment of the chromosome is reversed |
| Which one of the above is responsible for causing cri-du-chat? Burkitt’s lymphoma? | Deletion, translocation |
| What causes an abnormal number of chromosomes in a cell? | nondisjunction |
| What is aneuploid? | Individuals with extra or missing chromosomes |
| Individuals with a normal set of chromosomes | What is euploid? |
| An example of an aneuploidy is Down’s syndrome. This person has 47 chromosome instead of 46 due to having an | extra copy of chromosome 21 |
| XO – | Turner syndrome |
| XXY – | Klinefelter syndrome |
| XXX – | triple-X syndrome |
| What are the different types of genetic inheritance pattern? | 1. autosomal recessive traits 2. autosomal dominant traits 3. x-linked recessive traits |
| Examples of the autosomal dominant disorders/traits: | Achondroplasia Progeria Huntington’s disease 50% chance |
| Examples of the X-linked recessive disorders/traits: | Red-green color blindness Hemophilia Duchenne muscular dystrophy (DMD) 0% chance |