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GM Ethics

F215 Module 2

QuestionAnswerQuestionAnswer
What percentage of people on the organ donor list die while still on the waiting list? 60% What happens when engineered human nucleotidase enzyme (E5'N)is put into pig cells in culture? Reduced the activity of a number of immune cell activities involved in xenotransplant rejection
How can you decrease the risk of organ rejection? Compatability of organs are checked and after transplant surgery, immuno suppressant drugs are used
In 2003, Pigs were engineered to decrease the risk of organ rejection, how was this done? Pigs were engineered to lack the α-1,3-transferase enzyme (the enzyme that is a key trigger for graft rejection in humans)
What is the α-1,3-transferase enzyme and what does it do in relation to translpant organs? It is an enzyme that is a key trigger for graft rejection in humans, α-1,3-transferase enzyme creates antigenns that triggers an immune response
What is Xenotransplantation? The use of organs from a different species of animal for organ transplants
When transplantation is possible, what main risk is prone to happen due to foreign tissue? Trigger of an immune response
When an immune response occurs within the body to a foreign tissue, what does this cause? Organ rejection
Created by: indipindi99
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