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DIT RDE
Rate determining enzymes of metabolic processes
Process | Enzyme |
---|---|
Glycolysis | Phosphofructokinase-1 (PFK-1) |
Gluconeogenesis | Fructose-1,6-bisphosphatase |
TCA cycle | Isocitrate dehydrogenase |
Glycogen synthesis | Glycogen synthase |
Glycogenolysis | Glycogen phosphorylase |
HMP Shunt | Glucose-6-phosphate-dehydrogenase (G6PD) |
De novo pyrimidine synthesis | Carbamoyl phosphate synthetase II |
De novo purine synthesis | Glutamine-PRPP amidotransferase |
Urea cycle | Carbamoyl phosphate synthetase I |
Fatty Acid Oxidation | Carnitine Acyltransferase I |
Fatty Acid Synthesis | Acetyl-CoA carboxylase (ACC) |
Ketogenesis | HMG CoA synthase |
Cholesterol synthesis | HMG CoA reductase |
Heme synthesis | Aminolevulinate Synthase |
Bile synthesis | 7-alpha hydroxylase |