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Path Ch 9 Environmen
LECOM Path Ch 9 environment nutritional
| Question | Answer |
|---|---|
| Phase I reactions are | Reduction, Hydrolysis, Oxidation (RHO) |
| Air particles are more pathogenic at what size? | Smaller 10um |
| Characteristic in acute carbon monoxide poisoning in whites | cherry red skin |
| RBCs with basophilic stippling points toward what type of poisoning | lead |
| Poor epiphyseal growth with hyperdense cortices on x-ray in child | lead |
| Tremor, gingivitis, bizarre behavior | mercury poisoning |
| The developing brain is very sensitive to what type of mercury | methyl mercury |
| Hyperpigmented skin, hyperkeratosis, numbness, and parasthesias caused by what poison? | arsenic |
| Obstructive lung disease due to alveolar macrophage necrosis, kidney damage, and osteoporosis, osteomalacia. Metal causing it? | cadmium |
| Benzene leads to | AML |
| Polycystic hydrocarbons lead to | lung and bladder cancer |
| DDT, PCB, and dioxin do what? | block endocrine receptors |
| Vinyl chloride causes what | angiosarcoma of the liver |
| MC exogenous cause of human cancers | tobacco |
| This can be measured in the blood to measure second hand smoke | continineP Metabolite of ethanol that is toxic |
| Is NAD or NADH increased with ethanol break down | NADH |
| Increased NADH/NAD ratio in alcoholics causes what acid-base disturbance | lactic acidosis |
| HRT causes what | increased breast cancer, hypercoagulable state |
| Oral contraceptives cause | thromboembolism, CVD, reduce endometrial and ovarian cancer, Hepatic adenoma |
| Anabolic steroids can cause this liver disease | hepatic cholestasis |
| 50% of acute liver failure in the US is caused by | acetaminophen |
| Penetrave vs perforate | you penetrate tissue you perforate when you enter tissue and cause an exit wound |
| Burn of just the epidermis | superficial 1st degree |
| Burn to the dermis | 2nd degree or partial thickness |
| Burns down to subcutaneous tissue | 3rd degree or full thickness |
| MCC of infection in burn Pt | pseudomonas aeruginosa |
| You stop sweating in heat stroke or exhaustion? | stroke |
| Heat stroke is caused by | peripheral vasodialation with venous pooling |
| Rhabdo in heat stroke is caused by injury to what? | RYR1 |
| What reaches high concentration intracellularly in hypothermia | salts |
| Ionizing radiation comes in these 5 forms | x-ray, gamma rays, high-energy neutrons, alpha and beta particles. |
| Radiation causes | fibrosis and fibrointimal thickening and arteriolar sclerosis |
| You are considered malnourished when your BMI drops below | 16 |
| Children are considered malnourished when they drop to what percent below normal | 80% |
| What are the two protein compartments in your body | somatic and visceral |
| Marasmus effects what protein compartment more | somatic |
| Kwashiorkor effects which protein compartment more | visceral |
| Serum albumin levels in Marasmus and Kwashiorkor | normal in marasmus drastically depleted in kwashiorkor |
| This is seen in the urine of weight losing Pt’s with pancreatic, breast, colon and other cancers | PIF |
| This has the highest death rate of any psychiatric disorder | Anorexia nervosa |
| Sudden death from anorexia nervosa and bullemia is caused by | cardiac arrhythmias from hypokalemia |
| 4 Fat soluble vitamins | Vit DEAK |
| Pancreatic disturbances cause what type of Vitamin deficiency | fat soluble DEAK |
| Night blindness, corneal ulcers, keratinizing metaplasia | Vitamin A deficiency |
| HA, vomiting, dizziness, bone pain | Vit. A toxicity |
| Rickets in children, osteomalacia in adults | Vit D defic |
| Tetany and rachitic rosary | Vit. D def |
| Spinocerebellar degeneration | Vit E deficiency |
| Hypocoaguable states | Vit K deficiency |
| Dry/Wet beri beri, Korsakoff or Wernicke syndromes | B1 thiamine def |
| Cheilosis, stomatitis, glossitis | B1 def |
| Jbleeds and poor healing, bleeding gums, thinned osteoid matrix | Vit c deficiency, scurvey |
| 2 molecules produced by adipose tissue that make you skinny | leptin and adiponectin |
| Only molecule that makes you eat more. What produces it? | Ghrelin; stomach |