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(TAMUCC) Bio Ch. 8
Ch. 8- Intro. to Metabolism
| Question | Answer |
|---|---|
| totality of an organism's chemical reactions | metabolism |
| smaler molecules are made into larger molecules; ATP required; heat is released | anabolism |
| larger molecules are broken down into smaller molecules; ATP releasing; heat is released | catabolism |
| Which type of metabolism is the building up process? | anabolism type |
| Which type of metabolism is the breaking up process? | catabolism type |
| smaller molecules + ATP; larger molecules | = anabolism |
| larger molecules; smaller molecules + ATP | = catabolism |
| a series of linked reactions that begin with a specific reactant and produce an end product; each step is catalyzed by a specific________ | metabolic pathways; enzyme |
| What are the two types of metabolic pathways? | catabolic and anabolic pathways |
| releases energy by breaking down complex molecules into simpler compounds Ex:) cellular respiration | catabolic pathways |
| consumes energy to build complex molecules from simpler ones Ex:) photosynthesis | anabolic pathways |
| the ability to two work or bring about change | energy |
| How is energy measured? What unit of measurement is used? | measured as heat content with units of calories or joules; 1 cal, 1 joule |
| What are the two forms of energy? | kinetic and potential energy |
| energy in motion Ex:) light energy, mechanical energy, electrical, thermal | kinetic |
| energy that matter possesses because of its location or structure Ex:) chemical energy (food, gas, wood), gravitational energy | potential |
| What is the first law of thermodynamics? | (Principle of Conservation of Energy) energy cannot be created nor destroyed, but it can be changed from one form to another |
| What is the second law of thermodynamics? | energy cannot be changed from one form to another without a loss of useable energy |
| Light energy from the sun is transformed from plants to ________ energy | to kinetic energy |
| When plants are eaten by animals, the chemical energy is transformed to __________ of energy | to potential of energy |
| When animals walk, move or run, the chemical energy is transformed to ____________ energy | transformed to kinetic energy |
| What is released to the environment when energy is transformed from one form to another? | ATP or heat |
| every that can do work when temp. and pressure are uniform, as in a living cell | free energy |
| If G<0, what does it mean? | -spontaneous -reactants have more free energy than the products -"downhill" reaction |
| If G>0, what does it mean? | - not spontaneous - reactants have less energy than the products - "uphill" reaction |
| proceeds with a net release of free energy and is spontaneous | exergonic reaction |
| name types of cellular work | mechanical, transport, chemical |
| a catalytic protein that speeds up chemical reactions | enzyme |
| chemical agent that speeds up a reaction without being consumed by the reaction | catalyst |
| Are enzymes very specific for the reactants (substrates)? Are enzymes consumed after the reaction? | yes; no |
| name the components of an enzyme | apoenzyme and cofactor |
| protein part | apoenzyme |
| non-protein part | cofactor |
| The whole enzyme is called ______________ | holoenzyme |
| True or False. Cofactors can be inorganic or organic? | True |
| What are examples of inorganic cofactors? What are examples of organic cofactors? | Mg2 + Ca2; vitamins and coenzymes |
| The region on the enzyme where the substrate binds is called | active site |
| The reactant than an enzyme acts on is called | substrate |
| The complex that is formed when enzyme binds to its substrate | enzyme-substrate (ES) complex |
| lipids, lactose | substrate |
| lipase, lactase | enzyme |
| oxidation, reduction = | =reaction |
| oxidase, reductase = | =enzyme |
| Enzymes can lower the activation energy (EA) barrier by? | Orienting substrates correctly, straining substrates bonds, providing a favorable microenvironment, covalently bonding to the substrate |
| initial energy needed to start a chemical reaction | activation energy |
| In the induce-fit model of enzyme action, which changes in shape: the enzyme or the substrate? | enzyme |
| What chemical bonds hold the enzyme-substrate complex? | hydrogen bonds and ionic bonds |
| What are the factors that affect rate of enzyme activity? | -Temp. -pH -Concentration of enzyme -Concentration of substrate |
| What is the affect of temp. on the rate of enzyme action? | low temp- low rate of reaction increasing temp- increasing rate of reaction high temp- denatures enzyme- decreased rate of reaction |
| What is the effect of pH on the rate of enzyme action? | very low pH- denatures enzyme- low rate of reaction increasing pH- increasing rate of reaction high pH- denatures enzyme- decreased rate of reaction |
| What is the effect of enzyme concentration on the rate of enzyme action? | low enzyme conc.- low rate of reaction increased enzyme conc.- increasing rate of reaction adding more enzymes- no increase in the rate of reaction |
| What is the effect of substrate concentration on the rate of enzyme action? | increasing substrate conc.- increasing rate of reaction adding more substrate- no increase in the rate of reaction |
| two types of enzyme inhibitors | competitive and noncompetitive |
| binds to active site | competitive inhibitor |
| doesn't bind to active site | noncompetitive inhibitor |
| examples of enzyme inhibitors | toxins, poisons, pesticides, and antibiotics |
| What are two processes involved in regulation of enzyme activity? | allosteric regulation and feedback inhibition |