Save
Upgrade to remove ads
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

NURS 472 Adrenergic

Pharm - adrenergic drugs

QuestionAnswer
properties of catechols have neighboring -OH --> not orally absorbed (IV admin), do not cross BBB so no CNS effects
properties on non-catechols non-neighboring -OH --> oral absorption, cross BBB to exert CNS effects
Alpha-1 receptor normal functions vasoCon, mydriasis, bladder/prostrate sphincter contraction
Alpha-1 therapeutic uses to increase BP, hemostasis, releive nasal congestion, local anesthesia adjunct, mydriasis
ADRs of Alpha-1 activation HTN (too much of good thing), brady compensatory, necrosis extravasation
Beta-1 normal functions cardiac stimulation (force, frequency, AV conduction), kidney --> renin
Beta-1 therapeutic uses tx of cardiac arrest, HF, AV heart block, shock
Beta-1 ADRs tachy overshoot, dysrhythmias, angina pectoris (bwo increased heart activity exceeding what coronary artery can provide)
Beta-2 normal functions bronchoDIL, uterine relaxation, vasoDIL-essential, glycogenolysis, skeletal muscle contraction, HYPERkalemia
Beta-2 therapeutic uses asthma, delay tocolysis
Beta-2 ADRs hyperglycemia, tremor, HYPOkalemia (intracellular K shunting)
Dopamine receptor blurb PNS only in kidney vasculature -->increase RBF--> increase urine output
All Adrenergic agonists are catechols EXCEPT terbutaline, ephedrine
how must chatechols be administered must be IV admin, not absorbed orally, SHORT ACTING due to peripheral COMT, do NOT pass BBB, no CNS effect
What catechol activates all 4 receptor types epinephrine
epinephrine indications cardiac stimulation, anaphylactic shock(slanted towards Alpha-1, Beta-1)
epinephrine ADRs HTN overshoot, dysrhythmias, angina, necrosis extravasation, HYPERglycemia
What endogenous substance and 2 drugs activate Alpha-1, Alpha-2 and Beta-1 Norepinephrine, levarterenol, levophed
Norepinephrine activates these receptors with this indication Alpha-1,2 and Beta-1. Indicated for cardiac. CANNOT tx asthma or tocolysis because no Beta-2
What is the only drug that acts on Beta-1, Beta-2 nonselectively isoproterenol
What is isoproterenol indicated for cardiac stimulation, bronchoDIL
ADRs of Isoproterenol (B-1, B-2) B-1: tachy, dysrhythmias, angina. B-2: hyperglycemia, hypokalemia
what is therapeutically relevant about norepinephrine, levarterenol and levophed this class can treat both cardiac and blood pressure bwo A-1, A-2 and B-1 stimulation
In what order does dopamine 'step up' with increased dosage dopa receptors, B-1 receptors, A-1 receptors, with respective ADRs at each receptor
what drug activates Beta-1 selectively dobutamine
what is indication of dobutamine to stimulate heart in CHF
major ADRs of dobutamine B-1 ADRs of tachy, dysrhythmias, angina
what drug activates Beta-2 selectively terbutaline, which is a NON-catechol, so it can be given oral and it DOES cross BBB
terbutaline indicated for asthma, tocolysis
what NONcatechol activates all 4 receptors ephedrine - like an oral epinephrine
what little use does ephedrine have today pre-tx IV contrast, nasal decongestant, asthma, allergy, postural orthostasis
besides usual ADRs relevant to receptor type, what other ADR does ephedrine have because it is a NONcatechol, it can cross BBB and stimulate CNS-->insomnia
epinephrine catecholamine activates all 4 receptors
norepinephrine catecholamine activates A-1,A-2, B-1
levarterenol catecholamine activates A-1, A-2, B-1
levophed catecholamine activates A-1, A-2, B-1
dopamine activates dopa first, B-1 second, A-1 third
dobutamine selective B-1
terbutamine selective B-2 NONCATECHOLAMINE
ephedrine activates all 4, NONCATECHOLAMINE
Created by: lorrelaws
Popular Nursing sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards