click below
click below
Normal Size Small Size show me how
History, DNA replica
History, DNA Replication
| Question | Answer |
|---|---|
| Bacterial Transformation | Griffith performed experiments on mice and bacterial strains. Discovered that bacterai have the ability to transform harmless cells into virulent ones. |
| Transformation Factor is DNA | Avery, MacLoud, McCarty proved DNA was the agent that carried genetic characteristics from virulent dead bacteria to living nonvirulent bacteria |
| DNA not protein coat infecting bacteria | Hershey and Chase tagged the protein coat and the DNA bacteriaphages with radioisotopes to trace the path of the bacteriophage. |
| DNA in helix pattern | Rosiland Franklin. X-ray crystallography analysis of DNA. |
| Double helix model of DNA | Watson and Crick constructed model of DNA based on findings of other scientist. |
| DNA replicates in a semiconsertative fashion | Meselsohn and Stahl cultured bacteria with heavy and light nitrogen to trace DNA as it replicated and divided. |
| DNA | double stranded polymer of repeating units of nucleotides |
| adenine, thymine, cytosine, guanine | nitrogen bases that are part of the DNA nucleotides |
| Hydrogen bonds | bond that hold the DNA bases together |
| antiparallel | term used to describe the direction of complimentary DNA strands |
| RNA | single stranded polymer of repeating units of nucleotides |
| Uracil | replaces thymine in RNA |
| Template strand | single strand of DNA used for replication |
| replication fork | at end of replication bubble,y-shaped region where elongation occurs |
| DNA polymerase | enzyme that catalyzes elongation of new DNA strands. new strand built from 5' to 3', proofreads new strand |
| RNA Primer | preexisting chain of RNA used in DNA replication |
| Primase | enzyme, joins RNA nucleotided to make RNA primer |
| Helicase | enzyme, untwist the double helix at replication fork |
| telomere | found in Eukaryotes, nonsense nucleotide sequences at END of chromosome, protection against the loss of gene codes during replication |
| telomerase | enzyme, create and maintain telomeres |
| DNA ligase | joins Okazaki fragemnts that are replicating away from the replication fork |