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Pharm Ch 11 Gaba

LECOM Pharm Ch 11 GABA

QuestionAnswer
Inhibits GAT-1 Tiagabine
Inhibits GABA-T vigabatrin
Midazolam MOA and Duration Benzo; potentiate GABA & Short
Chlorazepate MOA and Duration Benzo; potentiate GABA & Short
Triazolam MOA and Duration Benzo; potentiate GABA & Short
Zolpidem MOA and Duration Benzo; potentiate GABA & Short
Alprazolam MOA and Duration Benzo; potentiate GABA & Intermediate
Lorazepam MOA and Duration Benzo; potentiate GABA & Intermediate
Estazolam MOA and Duration Benzo; potentiate GABA & Intermediate
Temazapam MOA and Duration Benzo; potentiate GABA & Intermediate
Chlordiazepoxide MOA and Duration Benzo; potentiate GABA & Long
Clonazepam MOA and Duration Benzo; potentiate GABA & Long
Diazepam MOA and Duration Benzo; potentiate GABA & Long
Flurazepam MOA and Duration Benzo; potentiate GABA & Long
Quazepam MOA and Duration Benzo; potentiate GABA & Long
Short acting benzo that treats insomnia triazolam
(2) intermediate acting benzos that treat insomnia estazolam and temazapam
(2) long acting benzos used for insomnia Tx Flurazepam and Quazepam
Short acting Benzo used with Pre- anesthetic midazolam
(2) long acting benzo’s used for anxiety chlordiazepoxide and Diazepam
Benzo used for insomnia with decreased muscle relaxant/anxiolytic action Zolpidem
Fast onset benzo for insomnia used intermittently Triazolam
Long acting benzo used as a muscle relaxant Diazepam
MOA of barbituates increases time Cl- channels stay open
2 ultra-short acting Barbs Thiopental and Methohexital
3 short acting Barbs Pento- Seco-, Amo-barbital
Long acting Barb Phenobarbital
Long acting barbiturate that undergoes hepatic and renal clearance phenobarbital
Used as single bolus injection for rapid anesthesia etomidate
Used for rapid or prolonged anesthesia, commonly leads to cardiovascular depression propofol
Used to treat spasticity; oral or intrathecally Baclofen
Used in ALS treatment Riluzole
Slows Alzheimer’s disease memantine
Used with Levadopa for treatment of Parkinson’s dyskinesia amantadine
Long acting benzo used for seizures Clonazepam
Used to reverse benzo’s Flumazenil
3 benzos used IV for general anesthesia Midazolam, Lorazepam, Diazepam
Benzo with less rebound insomnia Flurazepam
2 ultra-short acting drugs used to induce anesthesia by prolonging the time Cl- channels are open thiopental and Methohexital
Benzo that can be absorbed transmucosally methohexital
Treats raised intracranial pressure by prolonging the time Cl-channels are open thiopental
Created by: csheck