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CH-281: Ch. 4

Ch. 4: Energy, Enzymes, and Biological Reactions

QuestionAnswer
Activation Energy the initial input of energy required to tart a reaction
Active site the region of an enzyme
Active Site the region of an enzyme to which substrate(s) bind and where catalysis occurs
Allosteric Activator molecule that converts an enzyme with an allosteric site, a regulatory site outside the active site, from the inactive form to the active form
Allosteric inhibitor molecule that converts an enzyme with an allosteric site, a regulatory site outside the active site, from the active form to the inactive form
Allosteric regulation specialized control mechanisms for enzymes with an allosteric site, a regulatory site outside the active site, that may either slow or accelerate activity depending on the enzyme
Allosteric Site a regulatory site outside the active site
Anabolic pathway a metabolic pathway in which energy is used to build complicated molecules from simpler ones; also called a biosynthetic pathway. an individual reaction in an anabolic pathway is an anabolic reaction, also called a biosyntheic reaction
Anabolic Reaction metabolic reaction that requires energy to assemble simple substances into more complex molecules
ATP/ADP cycle the continual hydrolysis and resynthesis of ATP in living cells
Biosynthetic reaction an individual reaction in an anabolic pathway
Catabolic Pathway a metabolic pathway in which energy is released by the breakdonw of complex molecules to simpler compounds
Catabolic Reaction cellular reaction that breaks down complex moleculues such as sugar to make their energy available for cellular work
Catalysis the process of accelerating a chemical reaction with a catalyst
Catalyst substance with the ability to accelerate a spontaneous reaction without being changed by the reaction
Coenzymes organic cofactors that include complex chemical groups of various kinds
Cofactor an inorganica or organic nonprotein group that is necessary for catalysis to take place
Competitive inhibition inhibition of an enzyme reaction by an inhibitor molecule that resembles the normal substrate closely enough so that it fits into the active site of the enzyme
End-product inhibition in enzyme reactions, regulation in which the product of a reaction acts as a regulator of the reaction
Endergonic reaction reaction that can proceed only if free energy is supplied
Endothermic referring to a reaction that absorbs energy, that is, a reaction in which the products have more potential energy than the reactants
Energy coupling the process in living cells by which the hydrolysis of ATP is coupled to an endergonic reaction so that energy is not wasted as heat
Enthalpy the potential energy in a system
Entropy disorder, in thermodynamics
Enzyme protein that accelerates the rate of a cellular reaction
Enzyme specificity the ability of an enzyme to catalyze the reaction of only a single type of molecule or group of closely related molecules
Exergonic reaction reaction that has a negative DG because it releases free energy
Exothermic referring to a reaction that releases energy, that is, a reaction in which the products have less potential energy than the reactants
Feedback inhibition in enzyme reactions, regulation in which the product of a reaction acts as a regulator of the reaction. Also referred to as end-product inhibition
First law of thermodynamics the principle that energy can be transferred and transformed but it cannot be created or destroyed
Free energy the energy in a system that is available to do work
Kinetic energy the energy of motion
Metabolism the biochemical reactions that allow a cell or organism to extract energy from its surroundings and use that energy to maintain itself, grow and reproduce
Noncompetitive inhibition inhibition of an enzyme reaction by an inhibitor molecule that binds to the enzyme at a site other than the active site and, therefore, doesn't compete directly with the substrate for binding to the active site
Phosphorylation the addition of a phosphate group to a molecule
Potential energy stored energy
Ribozyme an RNA-based catalyst that is part of the biochemical machinery of all cells
Saturated enzymes enzymes for which increases in substrate concentration have no effect on the reaction rate
Second law of thermodynamics principle that for any process in which a system changes form an initial to a final state, the total disorder of the system and its surroundings always increases
Spontaneous reaction chemical or physical reaction that occurs without outside help
Substrate the particular reacting molecule or molecular group that an enzyme catalyzes
Thermodynamics the study of the energy flow during chemical and physical reactions
Created by: srooker
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