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Pharmocology Exam 1

FSC: Pharmocology Exam 1

Penicillins amoxicillin, PCN
Cephalosporins cefazolin, ceftriaxzone
Monobactams aztreonam
Carbapenems meopenem, ertapenem
Aminoglycosides genatmicin, streptomycin
Macrolides azithromycin, clarithromycin, erythromycin
Tetracyclines demeclocycline, doxycycline, minocycline
Lincosamide clindamycin
Oxazolidinone linezolid
Steptogramins dalfoprintin/quinupristin
Sulfonamides sulfadiazine sodium
Trimethoprim Primsol
Combonation Agents trimethoprim/sulfamethoxazole
Fluroquinolones ciprofloxacin, levofloxacin
acyclovir Epstein Barr, CMV, Herpes 1&2, Zoster
Amantadine Influenza A
Ribavarin Hanta,West Nile, RSV, Hep A&C
Oseltamavir Influenza A&B, Swine/Avian Flu
Acetylcystine prevents liver failure in acetominophen overdose
anti-depressents used for chronic pain amitryptyline (Elvail), sertraline (Zoloft)
Gabapentin anticonvulsant used for chronic pain, reduces rate of electrical transmission
Zolpidem (ambien) benzodiasepine used for insomnia
diphenhydramine (Benadryl) antihistamine used for insomina/as an antihistamine
amitriptyline (Elavil) anti-depressant used for insomina
Corticosteroids prednisone, solu-medrol (methlyprednisolone), hyrdrocortisone creame
COX1 Inhibitors Aspirin, Ibuprofen, Naproxen
COX2 Inhibitors Celecoxib
Leukotriene Inhibitor monolukast (Singulair)
Tetracyclines Acne, UTIs, skin/mucus membrane/respiratory tract infection, STIs, Rocky Mountain Spotted Fever, Lyme Disease, Typhoid, Anthrax!!!
Aminoglycosides burns, CNS/joint/bone/intra-abdominal infection, peritontis, sepsis, TB (streptomycin)
Floroquinolones skin infection, UTIs, respiratory tract infection, infectious diarrhea, gonorrhea, Anthrax!!!
Drugs used in treatment of TB Isoniazide, Rifampin, Pyrazinamide, Ethambutol
Azoles fluconizole (Diflucan), ketoconizole (Nizoral), clotimazole
Polyenes Amphotericin
Allylamines terbinafine (Lamisil)
Narcotic Agonists reverse adverse effects of narcotics
Flumazenil antidote, reverse effects of benzodiazepines
Side and Adverse Effects for: Opiate Analgesics NV, constipation/respiratory depression, addiction
Side and Adverse Effects for: NSAID risk for bleeding, HTN/asthma, salicylate poisioning, liver&kidney damage, heart attack, stroke
Side and Adverse Effects for: Acetaminophen /liver failure and kidney damage
Side and Adverse Effects for: Anti-depressents for pain constipation, dry mouth, urinary retention
Side and Adverse Effects for: Anti-convulsants for pain drowsiness, confusion, weakness
Side and Adverse Effects for: Benzodiazepine for insomina confusion, headache, NV, constipation, risk for falls/allergic reaction, addiction
Side and Adverse Effects for: Antihistamine for insomina drowsiness, loss of appetite, dry mouth, photosenstivity/
Side and Adverse Effects for: Anti-depressents for insomina dowsiness, hypotension, nightmares, slurred speech, tinnitus/
Side and Adverse Effects for: Corticosteroids sodium and fluid retention, HTN, buffalo hump/reduced immune system,adrenal supression, adrean insufficiency
Side and Adverse Effects for: Antihistamine sleepiness, tachycardia, blurred vision, urinary retention/seizuer, increased interoccular pressure, allergic reaction
Side and Adverse Effects for: Leukotriene Inhibitors headache, abd pain/liver impariment, allergic reaction
Side and Adverse Effects for: PCN, Carbapenems, Cephalosporins diarrhea/reduced kidney function
Side and Adverse Effects for: Vancomycin "red man syndrome"/reduced kidney function
Side and Adverse Effects for: Tetracyclines NVD, sore tounge, yeast infection in mouth & vagina/increased intracranial pressure, decreased kidney functioning, increased liver enzymes
Side and Adverse Effects for: Aminoglycosides NV, rash, letergy, fever, increased salivation/highly toxic to ears and kidneys, neuromuscular blockade
Side and Adverse Effects for: Macrolides NVD, abd pain, loss of appetite, change in taste/interfere with other drug metabolism (increase effects of digoxin and warfarin) which can cause cardiac dysrhytmias
Side and Adverse Effects for: Sulfonamides headache, fever, rash/crystalization in kidneys (kidney failure/stones), supression of bone marrow division, Steven-Johnson Syndrome, hepatitis
Side and Adverse Effects for: Trimethoprim headache, NV, itchiness/rupression of bone marrow division, Steven-Johnson Syndrome, hepatitis
Side and Adverse Effects for: Floroquinolones rash, NV, abd pain, dizziness, concentrates in urine causing burning/pain in urethra/increases warfarin levels, cardiac dysrhytmias, CNS issues (seizure), Steven-Johnson Syndrome, tendon rupture
Side and Adverse Effects for: Antiretrovirals /liver toxicity, worsening hyperglycemia, interactions with other drugs
Side and Adverse Effects for: Antituberculars /liver toxicity, peripehral neuropathy, drug inteaction
Side and Adverse Effects for: Antifungals /anemia, liver toxicity, anormal heart rhythms, reduced kidney functioning, Steven Johnson syndrome
Side and Adverse Effects for: Amphotericin B fever, chills (shake and bake), hypotension/shock
Mechanism of Action for: opiate analgesics bind to opioid receptor site altering perception of pain
Mechanism of Action for: NSAID supress inflammatory pathway
Mechanism of Action for: Acetominophen changes preception of pain and reduces severity of pain receptors
Mechanism of Action for: Narcotic Antagonists bind to, but do not activate, receptors
Mechanism of Action for: Benzodiazepine drugs for insomnia general depression of CNS
Mechanism of Action for: Antihistamine drugs for insomina produce drowsiness and mild sedation
Mechanism of Action for: antidepressants for insomina produce drowsiness and mild sedation
Mechanism of Action for: corticosteroids slows or stops pathways of inflammatory mediator response
Mechanism of Action for: Antihistamines histamine antagonist, binds to H1 histamine receptor sites, slowing or stopping tissue effects of inflammation
Mechanism of Action for: Leukotriene inhibitors prevent leukotriene production or block receptors
Mechanism of Action for: PCN, cephalosporin, carbapenems, vancomycin bind to cell wall proteins to prevent their inclusion in cell wall, inhibit enzyme needed to link wall components, activate enzymes which create holes in cell walls
Mechanism of Action for: Tetracyclines enter cell through special transporter, inside bind to ribosomes or prevent amino acid linking
Mechanism of Action for: Aminoglycosides, Macrolides enter cell through special transporter, binds to ribosome preventing it from reading RNA for protein sythesis. No bacterial protein is made, bacteria dies
Mechanism of Action for: Sulfonamides, trimethoprim prevents enzyme from converting substance into folic acid (necessary for cell growth)
Mechanism of Action for: Floroquinolones supress action of 2 enzyems within a cell improtant for bacterial DNA (prevents reproduction)
celebrex cross reactive with sulfa drugs
category 2 controlled substances codine, fentanyl, hyromorphone (Dilaudid), meperidien (Demerol), methadone, methylpehnidate (Ritalin), morphine, oxycodone (Percodan), pentobarbital, secobarbital
category 3 controlled substances Tylenol 3 or 4, Fiorinal, anabolic steroids
category 4 controlled substances benzodiazepines (Ativan, Valium, Xanax), chloral hydrate, paraldehyde, pentazocine, phenobarbital
category 5 controlled substances cough syrup w codeine, drugs for diarrhea that have small amounts of opioids (Lomotil)
Created by: kallenpoole
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